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46 Cards in this Set
- Front
- Back
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What are the acid neutralizing agents?
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Nacho3, caoh2, aloh3, mgoh2
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Antiflatulents?
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Charcoal and simethicone
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H2 receptor antagonists?
mnemonic starts with Hummer 2 |
Ranitidine, Famotidine, cimetidine, nizatidine,
H2 ran into a fan which fell over and out jumped Nazak. |
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H2 are ------------- ihibitors of -------------- secretions
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h2 antagonists are effective inhibitors of gastric acid secretions.
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--------------- inhibits several _ _ _ isozymes and other ------------ enzymes resulting in ----------- ---------------
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Cimetidine ihibits several cyp enzymes and other microsomal enzymes resulting in drug interactions
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H2 antagonists are useful in the management of --------- and --------------
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h2 antagonists are useful in the management of GERD and SRMD
(Stress related mucosal disease) |
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Stephens Zolliner syndrome?
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Excess production of gastrin
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What are the proton pump inhibitors?
Mnenomic? A Proton flew off the atom and hit the.... |
Lansoprazole, Rabeprazole, pantoprazole, omeprazole, esomeprazole.
A Proton flew off the atom. It hit a Rabbi and his pants fell down. He was then gored with a LANCE and fell On a Map and bled to death after a seesaw picked him up and bounced his corpse around. |
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Are Proton Pump Inhibitors better or worse than H2 antagonists?
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Better and safer.
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How long does it take for Proton Pump Inhibitors to kick in? Why?
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2 to 5 days due to the gradual inactivation of proton pumps.
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Protein pumps inhibitors are useful in the treatment of.....
mnemonic is An atom threw a pepsi.... |
Peptic Ulcers, Zollingers Stephens disorder, NSAIA ulcers, GERD
An atom threw a Pepsi. It hit Zollinger in the head. He takes an ibuprofen out of his gut roll for the pain. |
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What are the mucosal protective agents?
Mnemonic is Secret Service spit logeys on.... |
SUGAR packets that exploded BIZ MARKEE into bits that were eaten by MICE who then turned into ALGINATE.
Sucralfate, Bismuth Salts, Misoprostol, Alginic Acid |
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How does sucralfate work?
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Sucralfate is an aluminum salt that is activated by stomach acid and binds to ulcers to prevent further damage
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How does Bismuth Salt work?
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Similar to Sucralfate except that it binds up H pylori in peptic ulcer disease.
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What about Misoprostol? Concerns?
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it is an analog of prostoglandin e1, decreases stomach acid production and increases bicarbonate and mucous secretion. Dont use for pregnant or those with infamatory bowel disease.
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How about Alginic Acid?
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protects the espophagus from gastric acids (used in anti acids)
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What are the Gastric Motility promoting Drugs?
Mnemonic starts with GAS TRUCK... |
The GAS TRUCK with a METS hat on ran into a CESSPOOL. Someone came by and put a WREATH on his neck to mock him.
Metoclopramide, cisapride, erythromycin |
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How does Metoclopramide work?
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It is a 5HT4 agonist and dopinamergic antagonist that activates enteric ach causing it to get moving.
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How about Cisapride?
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Same as Meto but more toxic.
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How does Erythromycin stimulate gastric motility?
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Stimulate motilin receptors but causes diarrhea.
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What are the Anti Emetic Drugs Classes?
Mnemonic begins with barf on... |
Barf on the BENZ which crashes into a DECK of cards. A POT smoking DRONE stuffs the cards in CARBURETOR. A DOPE fiend comes along a takes HIT off the cards in the pipe. Then some HOMETEACHERS come by and PEE on his NECK.
Benzodiazapenes, Dexamethazone, Dronabinol, Phosporated Carbohydrate soln, Dopamine Receptor antagonists/Histamine, 5HT, Sub P Neurovascular drugs. |
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What does Dexamethazone do?
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Adjunct in treatment of chemotherapy.
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What about the Phosporalated Carb soln?
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Calcium reduces smooth muscle contractility
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What are the Dopaminergic drugs?
What do they do? Mnemonic... |
Metoclopramide, Prochlorperazine
MEET the PRO DOPE fiends. |
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What are the Anti Histamine drugs?
MNemomic? |
prometh, meclizine, hydroxyzine, diphenylhydramine
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What are the anti histamine GI drugs
menmonic: Histology magaZINE (and benedryl of course) |
promethizine, hydroxyzine, meclizine, diphenyhrydamine
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HT3 Drugs?
Hometeachers.... |
Hometeachers playing TRON the game.
All the HT3 drugs have SETRON |
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NK1 Receptor Drugs?
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NIKE PREP Stars
Apreptant. It covers these barf centers so that the signal doesnt get through. |
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What are the Stimulant Laxatives?
Mnemonic an EXCITED toilet.... |
slapped maSCARA on CASTRO who was riding on a BISON
cascara, castor oil, bisacodyl |
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What is castor oil?
Mnemonic castro snorting... |
RICE....
ricinoliec acid |
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Bulk Laxatives, how do they work?
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Increase the amount of stuff in the lumen. This draws water in (increases bulk) keeping you nice and regular.
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Stool softeners?
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They work by emulsifing stuff making it easer to,uhm, work out shall we say. This is good for those with heart problems. glycerin suppositories and docusate are examples.
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docusate is....
DOCtors ATE |
DOC ATE Princess toadSTOOL
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Anti Diarrhea agents?
mnemonic: AGENT smith gets the rumble in the jungle and... |
a huge thing of PEPTO, barfs on a LEPER who jumps onto a DIVER mid air who are then attacked by an OCTOpus underwater.
Pepto Bismol, Loperamide, Diphenoxylate, octreotide. |
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Pepto Bismol does...
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pepto..... sulfide and dark staining. E coli binding to mucosa.
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Loperamide does...
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loperamide is omodium an opiate receptor duda that inhibits peristalsis. opium binds you up.
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ocreotide does...
mnemonic... octopus in the tide... |
An OCTOPUS bodysurfing in the TIDE holding PANCAKES.
octreotide inhibits pancreatic tumor secretions and other hypersecretory stuff. |
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Inflammatory Bowel Disease drugs are...
FlAMEthrower to the GUT... |
the person falls over they are ASA 5 (in deep doodoo). Then the BOSS puts the victim into a SALAd.
ASA 5 main anti inflammatory agent. BOS=Balsalazine, olsalazine, Sulfasalazine, SALAd |
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Immunouppresants of IBD
FLAME in the GUT is SUPPRESSED by.... |
A FOAM SPRAY (Cortisone) by a MERCHANT in AriZona INLICTED by putting the spray up the butt.
Foam spray= Cortizone foam/spray MERCHANT=Mercaptopurine ARIZONA=AZathriopine INLICT=infliximab |
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What to AZathriopine and MErcaptopurine do?
Mnemonic Arizone MErchants SELL |
DEATH!!!! (skull and crossbones) at low doses these agents inhibit the inflammatory effects.
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Infliximab does....
INFLICT the... |
INFLICT the CROW manuever To the FACE (TNF).
infliximab, tnf a in crohns disease. Think CROW manuever and inflicting it. |
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Irritable Bowel Syndrome is treated with...
Mnemonic on the TABLE a GUT... |
alosetron and tegaserod
on the table a LOSER played TAG. He never got anyone. alosetron and tegaserod. |
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alosetron:
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the loser HT sat on a STOOL and got ischemic colitis.
alosetron HT3 ischemic colitis. |
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tegaserod:
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GAS=CAR=4=HT4. The GAS hot ROD ran over the HT.
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Lubiprostone
Mnemonic LUBE up the STONE |
LUBE the STONE with CHLOROX and send it screaming down the BOWEL at the PREGNANT LADIES. (think bowling)
lubeprostone=constipation aide by chloride channels in the gut. Not for pregnant folks. |
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Alvimopan is...
Mnemonic ALVIN the Chipmunk ... |
cooked up some HEROIN in a PAN at a Quincinyera.
alvimopan: mu (opiate receptor) enteric blocker. Used for 15 doses. This blocks the constipating affects of analgesic opiates. |
