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112 Cards in this Set

  • Front
  • Back
thick opaque fibrous white outer covering of the eye
sclera
continuous with sheath of optic nerve

tendons of eye muscles attached to it
sclera
clear bulging surface in front of the eye
cornea
main refractive surface of the eye
cornea
What is the Corneal (blink) reflex ?
Consensual AND Direct Reflex that occurs when cornea is touched (bright light, loud noise will also do the trick)
What is Corneal astigmatism ?
abnormal curvature or imperfection in the corneal surface which leads to refractive errors and blurred images
layer of blood vessels and connective tissue between the sclera (white of the eye) and retina. It supplies oxygen and nutrients to the inner parts of the eye
choroid
What are the 2 fluid envts light passes thru between the cornea and retina?
1) Anterior chamber - aqueous humor
2) posterior chamber - vitreous humor
both muscular and vascular tissue, consisting of the cililary muscles and ciliary process
Ciliary body
control the shape of the lens giving it refractive power
ciliary muscles
secretes aqueous humor, a fluid that fills anterior and posterior chamber and serves to hydrate and nourish lens and cornea; essential for transparent state
ciliary process
Failure of adequate aqueous drainage of eye in which high levels of IOP can reduce blood supply to eye and eventually damage retina
Glaucoma
collects and drains aqueous humor into venous drainage of sclera
Canal of Schlemm
maintains shape of the eye thru fluid production, circulation & re-absorbtion.
Interocular fluid pressure
Accomodation: defn
Dynamic changes in the refractive power of the lens to see up close or far away
How is accomodation for near objects accomplished?
Accommodation for focusing on near objects involves the contraction of cillilary muscles, which reduces tension on the zonule fibers (suspensory ligaments) and allows the lens to relax.
How is accomodation for far objects accomplished?
Lens assumes flatter shape via zonule fibers
What are the two opposing forces that determine shape of the lens?
1) Elasticity of lens (tends to keep it rounded)

2) Tension exerted by zonule fibers thru contraction of ciliary muscles
How do zonule fibers relax, allowing for near vision accomodation?
Sphincter-like contraction of ciliary muscle
Two layers of the iris
1) Stroma - contains sphincter and dilator pupillae

2) epithelial pigmented area - gives eye color
How is the size of the pupil adjusted?
GVE component of III, Edinger Westphal
Mydriasis: ___________
Miosis: ___________
dilation;
constriction

Of pupil
_____ layers of retina contain cell bodies while _______layers contain synapses
nuclear ;plexiform
What layer of retina are rods and cones in?
Inner/outer segment layer
_________transduce light and terminate on bipolar and horizontal cells.
Photoreceptors (rods/cones)
mediate lateral interactions in outer plexiform layers
horizontal cells
mediate lateral interactions in inner plexiform layer
amacrine cells
terminate on ganglion and amacrine cells.
Bipolar cells
are output cells of retina, their axons exit retina at the optic disc or blind spot.
Ganglion cells
responsible for light induced changes in photoreceptors
Cylic GMP channels in the outer segment
What happens to rods
A) In dark
B) In light
A) In the dark cGMP levels are high, keeping Na channels open--> depolarization of rods

B) In light, absorption of photons causes a decrease of cGMP levels--> Na channels close --> hyperpolarization
Rods depolarized in ________ and hyperpolarized in _____.
dark; light
T/F light entering the eye passes thru all layers before reaching rods and cones (photoreceptors)
T
What is rhodopsin?
Protein in rods that bleaches in response to light. When it bleaches, it leads to a reduction in Na+ conductance --> hyperpolarization
What role does glutamate play in visual signal transduction?
When rods are depolarized, they release glutamate (in dark). When hyperpolarized they stop releasing it.
In dark, rhodopsin is ______ and glutamate is _______.
inactive; released
What are the 3 different cones?
S, M, and L (short, medium, and long) corresponding to what wavelengths they preferentially respond to. There is overlap
What is it called when you have all 3 cones types)?
Trichromat
Lacking red
Protanopia
Lacking green
Deuteranopia
Lacking S cone/blue (very rare)
Tritanopia
Cones or Rods
A) More sensitive to light
B) Specialized for daylight
C) High acuity/concentrated in fovea
D) Slow response time for dark adaptation
E) Fast response time for light adaptation
A) Rods
B) Cones
C) Cones
D) Rods
E) Cones
What are the following:
A) Scotopic
B) Mesopic
C) Photopic
They're levels of luminance.
A) Darkest, corresponds to starlight
B) Corresponds to moonlight
C) Daylight and indoor lighting
Rods are active during which luminance levels?
Scotopic and Mesopic
Cones are active during which luminance levels?
Mesopic and Photopic
What kind of receptors at optic disk?
NONE
Where are rods mostly found?
Periphery of retina
Genetic disease that Involves loss of rods, eventually leading to only fovea/cones.
Retinitis pigmentosa
enlargement of optic nerve caused by increases in ICP
papilledema
loss of lens elasticity with age, leading to lessened accomodation
presbyopia
Visual areas in temporal lobe are primarily concerned with ___________
object recognition.

Ventral "what" system.
Visual areas in parietal lobe are primarily concerned with ___________
spatial/motion info.

Dorsal "where" system
Visual part of thalamus
lateral geniculate nucleus
where ganglion cell axons exit retina
optic disk
Optic radiations are part of what?
portion of internal capsule
What is the pretectum?
small area that coordinates the pupillary light reflex
Where does vision info go once it passes the LGN?
Goes to striate cortex/primary visual cortex as well as other areas, including SCN
What is suprachiasmatic nucleus ?
Area of hypothalamus involved in regulating biological rhythms. Involved in detection of light
The RIGHT LGN will contain info from what?
LEFT visual field. So it gets info from NASAL retina of Left eye, and temporal retina of R eye
Retinal ganglion cells from (nasal, temporal) retina cross the optic chiasm
NASAL retinal ganglion cells cross (they're processing info from the temporal fields)
each optic tract contains fibers from the temporal retina of ______eye and nasal retina of __________eye
ipsilateral; contralateral
information from the (ipsi, contralateral) hemifield projects to the lateral geniculate nucleus
contralateral
What's the role of the superior colliculus?
Orients movements of head and eyes.
Layers of LGN
6 layers.

3-6: parvocellular - P pathway - form and detail

1-2: magnocellular - M pathway - motion
What do the parvocellular (3-6) layers of the LGN process?
P pathway. Process form and detail
What do the magnocellular (1-2) layers of the LGN process?
M pathway. Motion.
Which layers of LGN from ipsilateral eye?
2,3,5
Which layers of LGN from contralateral eye?
1,4,6
T/F Extrastriate areas play role in integrating visual scene to conscious perception. Each has a “map” of the world. Many of them are distorted such that there’s unequal representation.
T
What is Meyer's loop?
The part of the optic radiations that is in the temporal lobe, and contains fibers representing <b>inferior retinal quadrants (superior visual field)</b>
What part of optic radiations contains fibers representing the superior visual field (from inferior retinal quadrants)?
Meyer's loop
Lesion of Meyer's loop - sx
Damage to contralateral upper visual fields
The visual cortex contains a map of the (contra or ipsilateral visual field).
CONTRA
What part of visual space is overrepresented?
The central portion, corresponding to the macula.
What part of the primary visual cortex represents the UPPER part of the visual field?
The LOWER part of the cortex (lingual gyrus)
What part of the primary visual cortex represents the LOWER part of the visual field?
The UPPER part of the cortex (cuneus)
Visual cortex has how many layers?
6
Which layer of visual cortex receives input from thalamus?
4
Which layer(s) send axons back down to thalamus and brainstem/midbrain?
Layers 5 and 6
Mixing of the pathways from the two eyes first occurs where?
striate cortex.

Inputs from the two eyes remains segregated in ocular dominance columns of level 4, but then as layer 4 neurons send axons to other cortical layers, info from two eyes converges onto individual neurons.
What are the ocular dominance columns?
Inputs from the L and R eyes remains segregated because axons of LGN neurons terminate in alternating eye-specific columns withing cortical layer IV. These are the ocular dominance columns.
What are the blobs?
Groups of color sensitive cells
What are orientation-selective neurons?
Certain neurons in visual cortex respnd most vigorously to bars in certain arrangements/orientations within the cell's receptive field. The responses are cortical neurons are thus tuned to the orientation of edges.
The dorsal/where pathway is associated with what cell type in LGN?
Magnocellular
The ventral/what pathwy is associated with what cell type in LGN?
Parvocellular
What is an agnosia?
defect in recognition or meaning without a loss in the objective sensation. Not a sensory loss, it is the inability to recognize or attach meaning to stimuli.
inability to recognize familiar objects by visual means; readily recognized when nonvisual cues are available. Can be very specific:
visual agnosia
3 components of the <b>near response</b>
1) Accomodation : ciliary m contracts to thicken lens.

2) Convergence: medial rectus contracts

3) Pupillary constriction
Involuntary blinking of the eyelids elicited by stimulation (such as touching or a foreign body) of the cornea, or bright light or loud noise
Corneal/blink reflex
Afferent limb of corneal/blink reflex carried by what CN?
V1 (ophthalmic trigeminal)
Efferent limb of corneal/blink reflex carried by what CN?
CN VII / Facial
T/F Corneal/blink reflex is consensual
T
When one eye is exposed to light, the pupils of both eyes constrict
Pupillary response
consensual pupillary light response
Accompanied constriction of pupil when light is shone into the OTHER pupil
Afferent limb of pupillary light reflex
Optic nerve sends retinal ganglion fibers to pretectum which sends fibers to Edinger-Westphal nucleus
Efferent limb of pupillary light reflex
Edinger-Westphal nucleus sends preganglionic parasympathetic fibers to ciliary ganglion via CN III (oculomotor) --> postganglionic parasympathetics innervate pupillary constrictor muscles
Edinger Westphal nucleus involved in what?
Origin of preganglionic parasympathetic fibers to ciliary ganglion via CN III (oculomotor) --> postganglionic parasympathetics innervate pupillary constrictor muscles.

Efferent limb of pupillary light reflex
Pretectum role
region of neurons found between the thalamus and midbrain. It receives binocular sensory input from retinal ganglion cells of the eyes, and is the region responsible for maintaining the pupillary light reflex. Output is to Edinger-Westphal nucleus
Argyll Robertson pupils
bilateral small pupils that constrict when the patient focuses on a near object (they “accommodate”), but do not constrict when exposed to bright light (they do not “react” to light).

AKA prostitute's pupils
What is Adie's tonic pupil syndrome?
caused by damage to the postganglionic fibers of the parasympathetic innervation of the eye, usually by a viral or bacterial infection which causes inflammation, and characterized by a tonically dilated pupil.
Anisocoria
unequal pupils
Miosis
refers to the constriction of the pupils.
Mydriasis
refers to dilation of pupils
What change to vision would occur if the following happened:

Lesion one optic nerve
Monocular vision
What change to vision would occur if the following happened:

Lesion optic chiasm
Fibers crossing in optic chiasm include those from nasal region of each retina, which process the temporal visual fields. It would lead to <b>loss of temporal visual fields</b>.

<b>bitemporal heteronymous hemianopsia</b>
Anopsia: defn
defect in the visual field
Hemianopsia : defn
type of anopsia where the decreased vision or blindness takes place in half the visual field of one or both eyes
homonymous hemianopsia
loss of half of the visual field on the same side in both eyes

homonymous = the same
hemianopsia = defect affecting half of visual field
What change to vision would occur if the following happened:

Lesion one side of optic tract
Would lose contralateral visual field because you'd lose the ipsilateral temporal retina and contralateral nasal retina, which are processing the same visual field.

<b>contralateral homonymous hemianopsia</b>
What change to vision would occur if the following happened:

Lesion one side of optic radiations
contralateral homonymous hemianopsia
What change to vision would occur if the following happened:


Lesion to one cuneus gyrus
<b>contralateral inferior quadrantanopsia</b>

The cuneus gyrus is superior to lingual gyrus and processes INFERIOR visual field (from SUPERIOR part of retina). Therefore, the INFERIOR parts of BOTH visual fields would be gone
What change to vision would occur if the following happened:

Lesion to one lingual gyrus (or meyer's loop)
contralateral superior quadrantanopsia