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66 Cards in this Set

  • Front
  • Back
What is bolus?
a ball of chewed food mixed with saliva
What are Passive Transort and Active Transport?
Passive Transport = substances pass through the plasma membrane without and energy requirement

Active Transport = requires metabolic energy for the exchange
1. What is Simple Diffusion?
1. The free movement of molecules across the plasma membrane powered by unequal concentrations (kinetic energy only)
1. What is Facilitated Diffusion?
1. the binding of a lipid insoluble molecule to a lipid-soluble carrier (permease) to cross the membrane
1. What are 4 examples of lipid insoluble substances?
1. Hydrogen, sodium, cacium, potassium ions, glucose, amino acids
1. What do lipid insoluble molecules need to pass through a cell membrane?
Permease
1. Wha tis Osmois and why does it occur?
1. Osmosis is a diffusion process that moves water (solvent) through a membrane.

It occurs b/c of a difference in concentration on both sides of the membrane
1. What is an isotonic solution?
1. a solution in which the concentration of nonpenetrating solute such as sodium choloride qeualizes inside and outside the cell wall
1. What energy is used for active transport?
1. ATP
1. What type of transport mechanism does intestinal glucose use?
2. Describe this process
3. What direction does it move?
1. coupled transport
2. Sodium and glucose couple together and are pumped through the plasma membrane into the cell
3. One direction only (intestine to blood)
1. What is bulk transport and what two processes does it consits of?
1. Bulk transport is the movement of macronutrients and large particles through cell membranes by an energy-requiring process.
The 2 processes of bulk transport are exocytosis and endocytosis.
1. Describe Exocytosis
2. Descrive Endocytosis
1. Exocytosis = transfers hormones, nerotransmitters, and mucous secretions from inside the cell to outside the cell
2. the opposite.
1. What connects the pharanx to the stomach?
1. esophogus
1. what is peristalisis?
1. the rythmic expansion and contraction of the esophogus that propels smal round food masses down the esophogus.
1. What is the esophogeal sphincter?
1. A ring of smooth muscle at the end of the esophogus that allows the food mass entry into the stomach.
What 3 stimuli control the sphincters?
1. Nerves, hormones, and hormone like substances
1. What is the function of the partietal cells?
1. They exrete hydrocholoric acid via the gastric clands in the stomach to aid the digestion process
How much digestion takes place in the stomach and what are the two exceptions?
little digestion takes place in the stomach.
2 exceptions are aspirin and alcohol
1. What is chyme?
1. A slushy, acidic miscture of food and digestive juices.
1. How long does it take the stomach to empty after a meal?
2. How long can the stomach retain a high fat meal?
3. What controls the time and rate of the emptying of the stomach?
1. 1-4 hours depending on the meal
2. 6 hours
3. The nervous system via hormones and peristolic waves
1. What % of digestion occurs in the small intestine?
2. What are the first 3 sections of the small intestine?
1. 90% of all digestion = small intestine
2. Duodenum
jejunum
ileum
What section of the smal lintestine does most of the digestion?
jejunum
1. What are Villi?
1. fingerlike protrusions that absorbe nutrients in the intestines.
1. What system does the villi use to absorb nutrients and what type of energy powers it?
1. Active transport
2, ATP
1. What are the microvilli
1. small projections found on the villi that aborb carbs, proteins, lipids, electrolytes, alcohol, vitamins, and minerals
1. How much time does it take the GI tract to eliminate food start to finish?
1-3 days
1. Where is bile produce, stored, and secreted?
1. Produced by the liver
stored and secreted by the gallbladder
what is emulsification?
the digestion of lipid droplets by bile so the small intestine can absorb them.
What happens to bile once it has done it's job in the intestines?
Some bile is excreted in feces but most returns to the liver
1. What does the body do to protect the intestines from them hydrocholoric acid from the stomach?
1. The pancreas secrete alkali-containing juice to buffer the acids. Protects against uclcers and damage.
What are the other two names for the large intestine?
Colon, Bowel
1. What is the only significant secretion of the large intestine and what does it do?
1. Mucos
protects the intestinal wall and helps to bind fecal matter together
1. What is amylase?
1. amylase = salivary enzyme that attacks starch and reduces it to simple sugars
What is pancreatic amylase and where does it do it's job?
1. pancreatic enzyme that completes the hyrdolysis of starch into smaller glucose molecules... happens in the duodenum.
What macronutrient provides the most energy for intense aerobic exercise and in what proportion? ( %)
Carbohyrdate provides 80% of the energy for intense aerobic exercise.
What happens to monosaccharides once they cross the intestinal wall? ( 4 steps)
1. samll intestines epithelial cells secrete monosaccharides into the bloodstream for transport by capillaries to the hepatic portal vein.
2. Hepatic portal vein emties directly to the liver
3. the liver removes most of the glucose, fructose, and galactose.
4. peripheral tissues absorb the rest
Where does intestinal blood go once it leaves the intestines?
Goes to the liver
Where does lipid digestion begin and through what substance?
lingual lipase in saliva starts the lipid digestion process
1. What happens to lipids when they reach the stomach?
2. What happens to longer chain lipids (12-18 Carbon fatty acids)?
1. gastric lipase works along with lingual lipase to continue breaking down lipids.
2. long chain fatty acids are digested in the small intestine
What is CCK and what does it do?
CCK = peptide hormone released from the wall of the duodenum.

Controls the release of enzymes into the stomach and small intestine.
What are micelles and what happens to them in the digestive process?
Micelles = fat-bile salt culsters.
They form when water-insoluble monoglyceride and free fatty acid end products form lipid hydrolysis bind with bile salts.
They are broken apart into bile and triacyglycerides. Bile returns to the liver.
1. What are the 2 routes that triacyglycerols take once they are ready for absorbtion?
2. What determines the rout which they take?
1. hepatic portal system or lymphatic system
2. their chain length determines the rout (long chain travels to lymphatics)
1. What happens to medium chain Triacyglycerols in the hepatic portal system?
1. They bypass the lymphatic system and go straight to the liver for subsequent tissue use in energy metabolism.
1. What happens to long chain fatt acids once they are absorbed into the epithelial cells? (3 big steps)
1. They reform into triacyglycerols then combine with protein, cholesterol, and phospholipids to form fatty droplets called chylomicrons.
2. Chylomicrons move up through the lymphatic system into the neck where they are hydrolized by lipoprotein lipase
3. They are now free fatty acids and glycerol, and will be used by peripheral tissues,
1. how efficient is the protein digestion process (What % of feces is protein at the end)?
protein digestion = very efficient
3% protein found in feces
1. What are the final end products of protein digestion that are ready to be absorbed into the intestinal mucosa? (3)
1. simple amino acids, dipeptides, tripeptides
1. What is gastrin?
2. What 2 big functoins does gastrin perform?
1. Gastrin = peptide hormone that:
a. controls pepsins release from stomach wall
b. stimulates gastric hydrochloric acid secretion
What 5 objectives does the acidificatoin of ingested food achieve?
1. Activates Pepsin
2. Kills pathogens
3. improves Fe and Ca absorbtion
4. Inactvates hormones of plant and animal origin
5. denatures food proteins
1. About how much of protein is hydrolyzed in the stomach before it passes inthe duodenum?
1. Only about 15% - hyrolyzed by pepsin
1. Where are the final steps in protein digestion carried out?
1. small intestine
What is trypsin and what does it do?
Trypsin - enzyme produced by the pancrease that breaks protein down into tripeptides, dipeptides, and single amino acids.
What happens to free amino acids when they are ready for absorbtion by the intestinal walls?
a. they are coupled with Na+ for delivery to the liver through active transport via the hepatic vein.
1. What happes to dipeptides and tripeptides when they are ready for absorbtion by the intestinal wall? (2 big steps)
1. They are moved into the (intestinal) epithelial cells by a single membrane carrier that uses H+ for active transport.
2. once inside the cytoplasm they hydrolyze into amino acids and flow into the bloodstream
Where are amino acids and more complex proteins absorbed in the digestive process?
The small intestine
1. When amino acids reach the liver, one of three things occurs. What are the three possibilities?
1. conversion to glucose (glucogenic amino acids)
2. conerstion to fat (ketogenic amino acids)
3. Direct release into the bloodstream as albumin or free amino acids.
1. When free amino acids have been sent into the bloodstream by the liverl, what happens to them?
1. They synthesize into biologically important proteins, peptides (hormones), and amino acids derivitaves such as choline and phosphocreatine
How and where are vitamins absorbed in the digestive process?
Absorbed via passive process in the jejunum and ileum
1. What are fat soluble vitamins absorbed with in the small intestine?
2. once fat soluble vitamins are absorbed, what happens to them?
1. fat soluble vitamins are absorbed with dietary fat (90%)
2. chylomicrons and lipoproteins carry them to the liver and body's fatt tissues
Who absorbs calcium better, women or men?
Men
What process in the small intestine determines the absorbtion of water (both ingested and in food)
The passive process of osmosis
What 5 factors affect gastric emptying rage (GER)?
1. solution volume (+ volume = more GER)
2. caloric content (+ calories = less GER)
3. Meal osmoality
4. temperature (cooler increases GER)
5. pH - higher acidic food decreases GER
What 3 factors explain exercise-related alterations in nutrient and fluid absorbtion?
1. Exercise mode
2. Environmental Temp
3. Type of food/liquid ingested
What are the 2 positive health benefits for the GI tract that are gained by a PA lifestyle?
1. Increased GER
2. Reduced incidence of liver disease, gallstones, colon disorders and constipation
What dietary habits cause constipation the most?
high fat low water diets
What foods improve diarrhea and which foods should be avoided?
improve diarrhea = broth, tea, toast, and low-fiber potassium rich foods.

avoid lactose, fructose, caffeine, and sugar alcohols
What is functional dispepsia?
chronic pain in the upper abdomen without obvious cause.