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20 Cards in this Set

  • Front
  • Back

Inner cell mass divides into 2 layers

Epiblast -》 Embryo


Hypoblast -》 Yolk Sac

What happens @ embryonic pole

Implantation


Blastocyst contacts uterine Matrix

Cytotrophoblast

Inner layer of trophoblast


Interior to the the synctiotrophoblast

Synctiotrophoblast

Digest the uterine matrix starting @ Day 7

What happens during day 8

Synctiotrophoblast continues to expand


@ embryonic pole amniotic cavity forms


- some epiblasts detached-》 roof of amniotic cavity


= Amnioblasts

What happens during day 9

Implantation completed


- coagulation plug = scar at location


Amniotic cavity fully formed


Some cells of hypoblast line the trophoblastic cavity


-》 Form yolk sac (vitelline sac)


Synctiotrophoblast continues to expand


-》 forms trophoblastic lacunae (fluid filled cavities, feed embryo and remove waste)

Function of Trophoblastic Lacunae @ day 9 and day 13

Feed embryo and remove waste


Filled with maternal blood

What happens days 12-13

The synctiotrophoblast expansion-》 merges with maternal capillaries


-》 Trophoblastic Lacunae fill with maternal blood


Formation of Extra-embryonic mesoderm


-》 Surrounds the embryo, lines the Cytotrophoblast


Separation of the primary yolk sac from the cytotrphoblast =》 chorionic cavity


Second wave of Differentiation-》 Definitive yolk sac


Proliferation of the extra embryonic mesoderm @ embryonic pole


-》 suspends Embryo in the choorionic cavity

Extra-embryonic mesoderm

Lines the cytotrphoblast


Then proliferated and suspension the embryo in the chorionic cavity

Day 14 ( 2 weeks) Rules of 2

2 weeks


2 germ layers - Hypoblast and Epiblast


2 embryonic cavities - Amniotic Cavity, Yolk sac (Vitelline cavity)


2 components to trophoblast- Cytotrophoblast and Synctiotrophoblast

Formation of chorionic villi... 3 stages

Primary stem villus


- Cytotrophoblast invades Synctiotrophoblast


Secondary Stem villi


- Extra-embryonic mesoderm invades primary stem villi


Tertiary Stem Villi


- Mesoderm differentiates into CT and B.V.s connecting w/ those in embryo


Uteroplacental circulation established @ Day 21

2 parts of placenta

Chorion frondosum - embryonic component


Decidua basalis - maternal

Chroion frondosum

@embryonic pole


Embryonic contribution to the placenta

Decidua basalis

Maternal contribution to the placenta

Implantation gone wrong

Ectopic pregnancy


Placenta: Accreta - Deep implantation


Placenta Percenta - very deep implantation


Placenta previa - low implantation

Placenta Previa

Low implantation

Placenta Percreta

Deep implantation


Chorioonic villi -》 fully into Myometrium

Placenta accreta

Deep implantation reaches Myometrium

Causes of ectopic pregnancy

Infection - Fallopian tube salpingitis


Scarring - surgery in pelbis/ tubes


Smoking


IVF


Congenital


Endometriosis


Endometriosis

Ectopic fragments of uterine mucosa