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40 Cards in this Set

  • Front
  • Back

Epimysium

The outer connective tissue that surrounds an entire muscle holding it together.

Perimysium

The connective tissue sheath surrounding each muscle fasciculus.


fasciculus (fascicle)

A small bundle of muscle fibers wrapped in a connective tissue sheath within a muscle.

muscle fiber

An individual muscle cell.


Sarcolemma

A muscle fiber's cell membrane, a permeable lipid layer coated by proteins.


Endomysium

A sheath of connective tissue that covers each muscle fiber. (Incloses capillaries ect outside of the sarcolemma)

plasmalemma

Plasma membrane, the selectively permeable lipid bilayer coated by proteins that composes the outer layer of a cell.


transverse tubules (T-tubules)

Extensions of the sarcolemma (plasma membrane) that pass laterally through the muscle fiber, allowing nutrients to be transported and nerve impulses to be transmitted rapidly to individual myofibrils.

sarcoplasm

The gelatin-like cytoplasm in a muscle fiber.

sarcoplasmic reticulum (SR)

A longitudinal system of tubules that is associated with the myofibrils and that stores calcium for muscle action.

myofibril

The contractile element of skeletal muscle.

sarcomere

The basic functional unit of a myofibril.

type I (slow-twitch) fiber


A type of muscle fiber that has a high oxidative and a low glycolytic capacity, associated with endurance-type activities.

type II (fast-twitch) fiber

A type of muscle fiber with a low oxidative capacity and a high glycolytic capacity; associated with speed or power activities.

Glycolytic capacity

A measure of the maximum rate of conversion of glucose to pyruvate or lactate that can be achieved acutely by a cell.

force-velocity relation

Muscle force as a function of the speed of contraction, which is the number of total cross-bridges attached at various speeds of contraction.

Oxidative Capacity

A measure of a muscle's maximal capacity to use oxygen in microlitres of oxygen consumed per gram of muscle per hour.

length-tension relation

Muscle length and how much force can be generated at this length based upon sarcomete length.


excitation–contraction coupling

The sequence of events by which a nerve impulse reaches the muscle membrane and. leads to cross-bridge activity and thus muscle contraction


dynamic contraction

Any muscle action that produces joint movement.


concentric contraction

Any muscle action that produces muscle shortening.

eccentric contraction

Any muscle action in which muscle lengthens.

static (isometric) contraction

Action in which the muscle contracts without moving, generating force.

a-motor neuron

A neuron innervating extrafusal skeletal muscle fibers.

Motor unit

A single alpha-motor neuron and all the muscle fibers it innervates.

rate coding

Refers to the frequency of impulses sent to a muscle.

twitch

The smallest contractile response of a muscle fiber or a motor unit to a single electrical stimulus.

summation

A series of three stimuli in rapid sequence, prior to complete relaxation from the first stimulus, can elicit an even greater increase in force or tension.

tetanus

Highest tension developed by a muscle in response to stimulation of increasing frequency.

size principle

Principle asserting that the size of the motor neuron dictates the order of motor unit recruitment, with small-sized motor neurons being recruited first.

sliding filament theory

A theory explaining muscle action: A myosin cross-bridge attaches to an actin filament, and then the power stroke drags the two filaments past one another.

actin

A thin protein filament that acts with myosin filaments to produce muscle action.

Tropomyosin

A tube shaped protein that twist around actin strands fitting in the grove between them.

Troponin

A complex protein attached at regular intervals to actin strands and tropomyosin.

nebulin

A giant protein that coextends with actin and appears to play a regulatory role in mediating actin and myosin interactions. It stiffens the thin filament and augments cross-bridge interaction in skeletal musclehttps://www.pnas.org/content/115/41/10369

myosin

About two-thirds of all skeletal muscle protein is _________, the principal protein of the thick filament. Each ______ filament typically is formed by about 200 myosin molecules.

adenosine triphosphatase (ATPase)

An enzyme which is located on the myosin head, splits the ATP to yield adenosine diphosphate (ADP), inorganic phosphate (Pi), and energy.

titin

A protein that positions the myosin filament to maintain equal spacing between actin filaments. An array of proteins that stabilize the myosin.

cross-bridge

Each thick filament contains many such heads, which protrude from the thick filament to form _____________ that interact during muscle contraction with specialized active sites on the thin filaments.

power stroke

The tilting of the myosin head, caused by a strong intermolecular attraction between the myosin cross-bridge and the myosin head, that causes the actin and myosin filaments to slide across each other.