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68 Cards in this Set

  • Front
  • Back
Three general kinds of functional areas
•Sensoryareas

•Associationareas


•Motorareas

Sensory areas & Sensory association areas

•There is a sensory area for each of the major senses.

- Each Primary sensory cortex hasan association area that processes sensory information

Multimodal association areas

•Receive and integrate input from multiple regions of the cerebral cortex


Motor cortex

•Plansand initiates voluntary motor functions

Information processing

•Sensory information received by primarysensory cortex

•Information relayed to sensoryassociation area


•Multimodal association areas receiveinput in parallel from sensory areas


•Motor plan enacted

Sensory areas

•Cortical areas involved in consciousawareness of sensation


•Locatedin Parietallobes, Temporallobes, Occipitallobes


•Distinct regions of each lobe interpreteach of the major senses

Sensory Areas - Primary Somatosensory cortex

•Located along the postcentral gyrus


•Involved with conscious awareness ofgeneral somaticsenses


•Spatial discrimination


•Preciselylocates a stimulus


•Certainregions are more adept at distinguishing precise stimuli

Sensory Areas - Primary Somatosensory cortex (2)

•Projection is contralateral


- Cerebralhemispheres receivesensory input from the opposite side of the body


•Sensory homunculus


- Abody map of the sensory cortex

Sensory Areas - Somatosensory Association Cortex

•Lies posterior to the primary somatosensorycortex


•Integrates different sensory inputs


- Touch, Pressure


•Draws upon stored memories of pastsensory experiences


- Youare able to recognize keys or coins in your pocket without looking at them

Sensory Areas - Visual Areas

•Primary visual cortex


- Locatedis deep within the calcarinesulcus•Onmedial part of the occipital lobe


•Largestof all sensory areas


- Receivesvisual information that originates on the retina


- Exhibitscontralateral function


•Firstof a series of areas processing visual input

Visual association area

•Surroundsthe primary visual area


•Continuesthe processing of visual information - Analyzescolor, form, and movement•Complexvisual processing extends into


- temporaland parietal lobes

Sensory Areas - Auditory Areas

Primary auditory cortex


Function : Consciousawareness of sound•Soundwaves excite receptors in the inner ear•Impulsestransmitted to primary auditory cortex


•Location:


Superioredge of the temporal lobe

Auditory association area

•Liesposterior to the primary auditory cortex•Permitsevaluation of different sounds


•Processesauditory stimuli serially and in parallel


Posterolateral - “where” pathway


Anterolateral - “what”pathway


•Liesin the center of Wernicke’sarea


- Involvedin recognizing and understanding speech

Sensory Areas - Vestibular Cortex

•Responsible for


- Consciousawareness of sense of balance•Located in the posterior part of the insula


- Deepto the lateral sulcus

Sensory areas - Gustatory Cortex

•Function


- involvedin the conscious awareness of taste stimuli


•Location


- Onthe “roof”of the lateral sulcus

Sensory Areas - Olfactory nerves

•Lies on the medialaspect ofthe cerebrum


- Locatedin the piriformlobe


•Olfactory nerves transmit impulses to theolfactory cortex


-Providesconscious awareness of smells

Sensory Areas - Olfactory nerves (2)

•Part of the rhinencephalon—“nosebrain”•Includes


- The piriformlobe, olfactory tracts, andolfactory bulbs


•Connects the brain to the limbicsystem


- Explainswhy smells trigger emotions


•Involved with consciously identifying andrecalling specific smells

Visceral Sensory Areas

•Location


- Withinthe lateral sulcus


- Onthe insula lobe


•Receives general sensory input


- Pain, Pressure, Hunger

Motor Areas

•Cortical areas controlling motor function


- Premotorcortex, Primarymotor cortex, Frontaleye field, Broca’sarea


•All localized in posterior frontal lobe

Motor Areas - Frontal eye field

Frontal eye field


•Lies anterior to the premotorcortex


•Controls voluntary movement of the eyes


- Especiallywhen moving eyes to follow a moving target



Motor Areas - Brocas Area

Brocas area

•Located in left cerebral hemisphere •Manages speech production•Connected to language comprehension areas in posterior association area•A corresponding region in the rightcerebral hemisphere controls emotional overtones to spoken words










Multimodel Association Models









•Large areas of the cerebral cortex

•Receive sensory input from multiplesensory modalities & Sensoryassociation areas.


•Make associations between kinds ofsensory information

Multimodel Association Modelas (2)

Three multimodal association areas

•Posterior association area


•Anterior association area


•Limbic association area

Posterior Association Area

Located: at interface of visual, auditory, andsomatosensory association areas

•Integrates sensory information into unifiedperception


•Allows awareness of spatial location of body


• “Body sense”


•Related to language comprehension and speech

Posterior Association Area (2)

Dorsal stream : Extends to the postcentral gyrus •Perceives information about spatialrelationships•“Where” pathway—location ofobjects•

Ventral stream : Passes information into inferior part ofthe temporal lobe.


Responsible for recognizing objects, words, andfaces• “What” pathway—identifiesobjects

Posterior Association Area (3)
Multiple language areas in left cerebralcortex• Wernicke’s area functions in•

Speechcomprehension


•Coordinationof auditory and visual aspects of language.


Initiation ofword articulation


• Recognitionof sound sequences

Auditory Pathways

• Auditory stimuli processed in two streams• From auditory association area throughmultimodal association areas• Parietal lobeand lateral part of frontal lobe—evaluate location of sound stimulus• “Where” pathway

• Anteriorregion of temporal lobe and inferior region of frontal lobe—process soundidentification• “What” pathway

Posterior Association Area (4)

Areas in right cerebral hemisphere act in

-Creative interpretation of words


-Emotional overtones of speech

Anterior Association Area (1)

located: The prefrontal cortex (frontal lobe)• Receives information from posterior associationarea

•Integrates information with past experience


•Initiates and plans motor movements


•Has links to the limbic system


Functions include: More complex functions include all aspects of•Thinking, perceiving, intentionally remembering•Processing abstract ideas, reasoning, judgment•Impulse control, mental flexibility, socialskills•Humor, empathy, conscience


Anterior Association Area (2)

Functional neuroimaging techniques

Reveal functions of specific parts of theprefrontal cortex


•Anterior pole of frontal cortex


•Active in solving the most complex problems •More complex problems, emotions, cognition atanterior part of frontal lobe


Additional functions


•Stores information for less than 30 seconds•Three working memory areas•Visualworking memory•Auditoryworking memory•Executivearea

Limbic Association Areas

Located on medial side of frontal lobe

•Involved with memory and emotions•Integrates sensory and motor behaviors


•Aids in the formation of memory


•Processes emotions

Lateralization of cortical functioning

The two hemispheres control opposite sides ofthe body

•Contralateral = opposite side


•Hemispheres are specialized for differentcognitive functions


Left cerebral hemisphere—control over


•Language abilities, math, and logic


Right cerebral hemisphere—involved with•Visual-spatial skills


•Reading facial expressions


•Intuition, emotion, artistic and musical skills

Cerebral white matter

Different areas of the cerebral cortex • Communicate with each other

•Communicate with the brain stem and spinal cord•


Fibers communicating are


•Usually myelinated and bundled into tracts


Types of tracts


Commissures—composed ofcommissural fibers•Allowscommunication between cerebral hemispheres•


Corpuscallosum—the largest commissure


•Association fibers •Connectdifferent parts of the same hemisphere•Parts of Wernike’s and Broca’s areas are connected by association fibers

Types of tracts (continued)Projection fibers—runvertically •Descend fromthe cerebral cortex •Ascend to thecortex from lower regionsCorticospinal tracts begin with pyramidal cells

Projection Tracts

Internal capsule—projectionfibers form a compact bundle• Passes between the thalamus and basal nuclei

Corona radiata—superior tothe internal capsule•Fibers run to and from the cerebral cortex

Deep gray matter of cerebrum

Consists of

Basal nuclei (basal ganglia)•Involved inmotor control•Basal forebrain nuclei•Associatedwith memory•


Claustrum


- A nucleus ofunknown function


Amygdaloid body


•Located in cerebrum but is considered part ofthe of the limbic system

Basal Nuclei
•A group of nuclei deep within the cerebralwhite matter•Formed from

Caudate nucleus—arches overthalamus•Putamen


•Globus pallidus


Evidence shows that they•Start, stop, and regulate intensity of voluntarymovements• Select appropriate muscles for a task andinhibit others.


In some way estimate the passage of time

Basal Ganglia
•Complex neural calculators•Cooperate with the cerebral cortex incontrolling movement•Receive input from many cortical areas•Substantia nigra alsoinfluences basal ganglia
Basal Forebrain Nuclei
Structures composing basal forebrain nuclei•Septum

•Diagonal band of Broca


•Horizontal band of Broca


•Basal nucleus of Meynert


Basal Forebrain Nuclei (2)

Basal Forebrain Nuclei

Part of cholinergic system • That is, they synthesize and release acetylcholine


•Location


Anterior and dorsal to hypothalamus


•Functions related to


•Arousal •Learning •Memory •Motor control •Degeneration of basal forebrain nuclei


•Associated with Alzheimer’s disease

Functional Brain Systems: networks of neurons that function together

Networks of neurons functioning together Limbic system

Spread widelyin the forebrain


The reticular formation


Spans thebrain stem

Limbic System

Location


Medial aspect of cerebral hemispheres


Also within the diencephalon


Composed of


Septal nuclei, cingulate gyrus, and hippocampalformation•Part of the amygdaloid body


Fornix and other tracts link the limbic system together


Limbic System (2)

The “emotional brain”

Cingulate gyrus :


Allows us toshift between thoughts


interpretspain as unpleasant


- Hippocampal formation


• Hippocampus and the parahippocampal gyrus

Reticular Formation

Runs through the central core of the medulla,pons, and midbrain

•Forms three columns


Midline raphe nuclei


Medial nuclear group


Lateral nuclear group

Reticular Formation (2)

Widespread connections

•Ideal for arousal of the brain as a whole Reticular activating system (RAS)


Maintains consciousness and alertness Functions in sleep and arousal from sleep Malfunctions in people with narcolepsy

Protection of Brain

The brain is protected from injury by

The skull


Meninges


Cerebrospinal fluid


Blood brain barrier

Meninges

Functions of meninges

Cover and protect the CNS


Enclose and protect the vessels that supply theCNS


Contain the cerebrospinal fluid


Between piaand arachnoid maters

Dura Mater

Strongest of the meninges

Composed of two layers•Periosteal layer• Meningeal layer•Two layersare fused except to enclose the dural sinuses


Largest sinus - the superior sagittal sinus Dura mater extendsinward to subdivide the cranial cavity


Arachnoid Mater

Location

beneath the dura mater

Arachnoid villi


Project through the dura mater


Allow CSF to pass into the dural blood sinuses

Pia Mater

- Delicate connective tissue

- Clings tightly to the surface of the brain


- Follows all convolutions of the cortex

Cerebrospinal fluid (CSF)

Formed in choroid plexuses in the brainventricles

Choroid plexus is


-Located inall four ventricles


-Composed of ependymalcells and capillaries Arises from blood


-500 ml produced per day


-Only 100–160 mlpresent at any one time

Blood brain Barrier

Prevents most blood borne toxins from enteringthe brain

•Impermeable capillaries


Not an absolute barrier


•Nutrients such as oxygen pass through


•Allows passage of alcohol, nicotine, andanesthetics

Spinal Cord

Functions of

Spinal nerves attach to it


•Provides two-way conduction pathway


•Major center for reflexes


•Location


Runs through the vertebral canal


•Extends from the foramen magnum to the level ofthe vertebra L1 or L2

Spinal Cord (2)

Conus medullaris

•The inferior end of the spinal cord


Filum terminale


•Long filament of connective tissue


•Attaches to the coccyx inferiorly• Cervical and lumbarenlargements


Where nerves for upper and lower limbs arise Cauda equina


•Collection of spinal nerve roots

Spinal Cord Segments

Indicate the region of the spinal cord fromwhich spinal nerves emerge

•Designated by the spinal nerve that issues fromit


•T1is the region where the first thoracic nerve emerges

Spinal Cord; Two deep grooves

Two deep grooves run the length of the cord Posterior median sulcus

Anterior median fissure

White matter of the Spinal Cord

Outer region of the spinal cord Composed of myelinated and nonmyelinated axons

- Allow communication between spinal cord andbrain


Fibers classified by type


Ascending fibers


Descending fibers


Commissural fibers

Gray Matter of the Spinal cord

Shaped like the letter “H”

•Gray commissure—contains thecentral canal


Dorsal horns


Consist of interneurons


Ventral and lateral horns


Contain cell bodies of motor neurons


Regions of Gray Matter


Gray commissure


Dorsal horns


Ventral horns


Lateral horns

Gray Matter divided by somatic and visceral regions

Divided according to somatic and visceralregions

SS—somaticsensory


VS—visceralsensory


VM—visceralmotor


SM—somatic motor

Protection of Spinal Cord

Protected by vertebrae, meninges, and CSF Meninges

Dura mater—a singlelayer surrounding spinal cord


Arachnoidmater—lies deep to the dura mater Pia mater—innermostlayer


Delicatelayer of connective tissue


Extends tothe coccyx


Denticulateligaments—lateral extensions of pia mater

Cerebrospinal Fluid in Spinal Cord

Fills the hollow cavities of the brain andspinal cord

Provides a liquid cushion for the spinal cordand brain


•Other functions


Nourishes brain and spinal cord•Removes wastes•Carries chemical signals between parts of theCNS

Sensory and Motor pathways in the CNS

Multineuron pathways connect brainand body periphery

•Pathways are composed of tracts Ascending pathways—carryinformation to more rostral areas of the CNS


•Descending pathways—carryinformation to more caudal regions of the CNS

Ascending Pathways

Conduct general somatic sensory impulses•Chains of neurons composed of

First-, second-, and third-order neurons


Four main ascending pathways


Dorsal column pathway


Spinothalamic pathway


Posterior spinocerebellar pathway


Anterior spinocerebellar pathway

Descending Pathways

Most motor pathways

Decussate at some point along their course•Consist of a chain of two or three neurons•Exhibit somatotopy


•Tractsarranged according to the body region they supply


•All pathways are paired


•One of each on each side of the body

Descending Pathways (2)

Deliver motor instructions from the brainto the spinal cord

•Divided into two groups


•Pyramidal (corticospinal) tracts


•Other motor pathways


•Tectospinaltracts


•Vestibulospinaltract


•Rubrospinaltract


•Reticulospinaltract


Disorders of the central nervous system: Spinal Cord Damage

Spinal cord damage•

Paralysis—loss of motorfunction


Parasthesia—loss ofsensation


•Paraplegia—injury to thespinal cord is between T1 and L2


•Paralysis ofthe lower limbs


Quadriplegia—injury to thespinal cord in the cervical region• Paralysis ofall four limbs

Disorders of the central nervous system: Brain Damage

Brain dysfunction

•Degenerative brain diseases• Cerebrovascularaccident (stroke)


•Blockage orinterruption of blood flow to a brain region•


Alzheimer’s disease


•Progressivedegenerative disease leading to dementias

Disorders of the central nervous system: Congenital malformations

Congenital malformations

•Hydrocephalus


- Neural tube defects


•Anencephaly—cerebrum andcerebellum are absent


•spina bifida—absence ofvertebral lamina Cerebral palsy—voluntarymuscles are poorly controlled


•Results fromdamage to the motor cortex

Postnatal changes in the brain

Brain structures complete development atdifferent times

Critical periods in learning


Language


Some development occurs into early 20s Decline with age attributed to changes


In neuralcircuitry


Amount of neurotransmittersbeing released