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142 Cards in this Set

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What are elements? What 4 elements make up all living organisms?

Pure substances


Carbon, Nitrogen, Oxygen, & Hydrogen make up 98% of the body

What do "alone" & "not alone" mean with respect to elements?

"Alone"=pure form of an element


"Not alone" = combined elements

What is an atom? What are its 3 subatomic particles?

An atom is the smallest unit of an element that has all the properties of that element.



Has protons, neutrons, & electrons

What are the charges of he subatomic particles? Where are ey located?

Proton: positive (in nucleus)


Neutron: neutral (nucleus)


Electron: negative (electron orbital)

The atomic number is determined by

The number of protons in that atom

Atomic mass is determined by

The number protons + neutrons in that atom

In a neutral atom, the # of electrons

Equals the number of protons

Trace elements are

Elements found in very small % but are of great importance

Isotopes are

Atoms of the same element that have a different # of neutrons (I.e. C-12, C-13, C-14)

Half-life is

Time needed for 50% of atoms in a sample to decay

A hydrogen bond

Is an electrical attraction between hydrogen and some other element

One H20 can bond to a maximum of

4 other waters

Functional Group (OH); in alcohols & sugars

Hydroxyl Group

Functional Group (PO4)

Phosphate group

in highly charged phospholipids & nucleic acids

Functional group (S-H)

Sulfhydryl

found in proteins

Functional Group (N-H); in proteins and amino acids

Amino Group

A compound is

Two or more different atoms bonded chemically

How many electrons can each shell hold? How many for each orbital?

-1st shell: 2, 2nd shell: 8, 3rd shell: 8 (for biology purposes)



-Each orbital holds max of two electrons

Valence number is

The number of electrons in the last energy level (shell) of an atom

Carbon has 6 electrons, but its valence number is 4.

What's an ion? What's the difference between a cation & anion?

-an ion is an atom where the total number of electrons and protons don't equal, resulting in a net positive or negative charge



-A cation is a positively charged ion. An anion is a negatively charged ion.

What's a covalent bond? What's the difference between polar & nonpolar covalent?

-a covalent bond involves the sharing of electron pairs between atoms



-Polar covalent is unequal sharing (I.e. H2O). Nonpolar is equal sharing.

What's an ionic bond?

An electrically charged attraction between oppositely charged ions

Double bonds

Are bonds involving four bonding electrons (2 electron pairs) instead of the usual two electrons (one pair)

Why does water have positive and negative charges? Why is water polar?

Oxygen has a higher electronegativity that Hydrogen. This causes the bonding electrons to be more attracted to the hydrogen, making the oxygen region slightly more negative & the hydrogen region more positive.

Both of these questions really share the same answer. Think about the definition of polar bonding & how electronegativity relates to Oxygen & hydrogen.

Distinguish between a solute and a solvent

-The solute is what's being dissolved in a solution. The solvent dissolves the solute to form a solution.

What's a solution? What's an aqueous solution?

-A solution is a homogenous mixture of 2+ substances



-An aqueous solution is a solution where the solvent is H2O

"Aqueous" comes from the Latin word "aqua" meaning "water"

How are cohesion & adhesion related to H2O?

-Cohesion: water attracted to water (water drop)


-Adhesion: water attracted to other substances (water attached to a pine needle)

Both are properties of water and have to do with attraction, but there's a slight difference

How is surface tension related to H2O?

The relatively high attraction of H2O to each other causes each molecule to be pulled to each other, resulting in a surface "film" & no net movement of water

Think of when you fill a glass to the brim with water & it doesn't spill

What is heat of vaporization (of water)?

Amount of energy needed to transform a given quantity of a substance from a liquid to a gas @ a given pressure

What is the structure of ice? Why does it float?

-crystal lattice structure


-As water cools, the molecules have less energy & H bonding takes over. The water molecules form a crystal that makes the molecules space apart. This makes ice less dense that liquid water, so it floats.

What's pH? Distinguish between an acid & a base

-pH is a scale used to determine acidity or basicity of a solution. (Measure of the concentration of H+ ions in a solution)


-Acid has a pH of less than 7. Base has a pH greater than 7.

pH stands for "potential hydrogen"

The equation for ionization of water is

2H2O ---> H3O+ (+) OH-


<---

Functional Group (COOH)

Carboxyl

Found in acids

Functional Group (CH3)

Methyl

Nonpolar

Functional Group (CO)

Carbonyl

Found in aldehydes & ketones

Functional Group (COH)

Aldehyde

What are the four macromolecules?

Carbohydrates, lipids, proteins, nucleic acids

Macromolecules are synthesized from

Monomers

Single units that are called...

Adding water is called

Hydrolysis

When monomers are bonded together, 1 _____ is removed. His process is called

Water; dehydration synthesis

The Carbon/Hydrogen/Oxygen ratio for carbohydrates is

1:2:1

Think of glucose (C6H12O6)

Simple sugars are called______; 2 of these bonded together are ______; many of these bonded together are_____

Monosaccharides; disaccharides; polysaccharides

Starches are examples of _______; they are mainly used for_____

Polysaccharides; storage

What's the difference between alpha glucose and beta glucose?

-in alpha glucose, the OH's on the first & fourth carbon point in the same direction. In beta glucose, they point differently.

The monomer for polysaccharides is

An amino sugar

Chitin would be an example of this

These macromolecules are insoluble in water

Lipids

The monomer for a lipid is

A fatty acid

A.k.a. a long hydrocarbon chain plus a carboxyl group

What's the difference between saturated and unsaturated fats?

Saturated has no double bonds, solid at room temp & tend to be animal products.



Unsaturated has 1+ double bonds, are liquid at room temp & are plant based (olive, corn oil

3 main differences

Name functions of fats

-Long term storage of energy


-insulators


-form membranes


-steroids

Phospholipids have

1 glycerol, 2 fatty acids & a phosphate

Triglycerides consist of

A glycerol & 3 fatty acids

Functional Group (COO)

Ester

The protein monomer is

An amino acid

Dipeptide means

Two amino acids

The primary structure of a protein

Is the precise order of amino acids in a polypeptide chain

The secondary structure of a protein

Is the alpha-helix & beta-pleated sheet

The tertiary structure of a protein

Takes the helix sheet & folds back on itself

The quarternary structure of a protein

Is 2 polypeptide chains bonded together

Denaturation is

The process when proteins lose their confirmation (or fall apart)

Can be caused by temp increase and pH change

Protein functions include

Structural (hair, tendons); antibodies, storage, transport oxygen, enzymes, & movement

Why can lipids store 2x as much energy as carbs?

Because of their many C-H bonds (more H on a C = more energy)

The monomer of a polynucleotide is

A nucleotide

A nucleotide consists of

A 5 carbon sugar + a nitrogen base + 2 or 3 phosphates

The cell theory states

-the cell is the smallest unit of life


-cells arise only from other cells

2 things; concept by Schleiden & Schwann

What's the main differences between prokaryotes & eukaryotes?

-Prokaryotes have no nucleus, membrane bound organelles & one molecule of DNA.


-Eukaryotes have nucleus, M.B. organelles & more than 1 chromosome

What limits the size of a cell

The surface area to volume ratio

What is usually the largest feature of a cell

Nucleus

Contains genetic material & only found in run at totes

Chromosomes are the ______ form of _______

Condensed; chromatin

Every cell needs _____ because they are the site of______

Ribosomes; protein synthesis

Can be in free or attached form. "Free" makes proteins for the cell & the "attached" make proteins for export

Smooth ER

Synthesizes lipids, steroid hormones, can detoxify drugs in the liver

In the _____side of the Golgi body, proteins enter thru vesicles. In the ______ side, modified proteins exit

Cis; trans

What are 3 places you can find DNA in the cell?

Nucleus, Mitochondrion, Chloroplast

The main function of the mitochondrion

Is to produce most of the energy for the cell in the form of ATP

Peroxisomes

Detoxify alcohol, digest nucleotides & lipids

These are found only in plants & some protists. They produce ______ & ______ & contain several pigments.

Chloroplasts; sugar from CO2 & oxygen

Main pigment is chlorophyll

The "suicide bag" of the cell; digests food, foreigners & bacteria & participates in apoptosis

Lysosome

Acts as a storage space; large in plant cells and small in animal cells

Vacuole

Located only in plants (seeds) and responsible for the conversion of fats to carbs

Glyoxysome

3 elements of the cytoskeleton

Microtubules, intermediate filaments, microfilaments

Cilia & flagella both function in _______. In flagella, there is a ______arrangement of microtubules.

Movement; "9 and 2"

Name the 3 types of cell junctions

-desmosomes (weld 2 cells together two resist mechanical stress)


-tight junction (prevents fluid leakage)


-gap junction (cell cell communication)

What affects fluidity?

-amount of unsaturated phospholipids (increase in unsat phospho. = increase in fluidity)


-increase in temp = increase in fluidity


-increase in cholesterol = increase in fluidity

Channel proteins are called ______.

Aquaporins

Two types of transport. _______ requires no ______ while ______ requires ______?

Passive requires no energy while active requires energy.

Differentiate between Brownian motion, diffusion & osmosis.

-Brownian motion: molecules move & collide at random with no net movement


-Diffusion: movement of molecules from region of high to low concentration


-Osmosis: diffusion of water across a semipermeable membrane

Water always moves from ____tonic to ____tonic area


Hypo to hyper

Has a protein and favorable concentration gradient; requires no energy

Facillated diffusion

Na+/K+ pump is a carrier protein that keeps cell membranes

Polarized

Types of endocytosis

-Phagocytosis: engulfing bigger particulates


-Pinocytosis: smaller particulates: dissolves substances

Exocytosis

Substances exit the cell

Define metabolism, anabolism, catabolism.

Metabolism: chemical reactions


Anabolism: build up of molecules, requires Energy


Catabolism: break down of molecules, release Energy

Exergonic v Endergonic

-exergonic reactions release energy (release Hydrogen) & has negative delta G


-endergonic require energy (add H), positive delta G

Reduction vs Oxidation

Reduction: requires energy; adds H to C


Oxidation: releases energy

Coupled reactions

Supply energy to reactions

Coenzymes are

Electron acceptors & donors

They're not enzymes by the way.

Catalysts are ______. And how do they accomplish their function??

Enzymes that speed up chemical reactions; they do this by lowering the activation Energy of a reaction

A substrate binds at

The active site

What can influence enzyme activity?

Temperature, pH, inhibitors (competitive & noncompetitive; reversible & irreversible)

What is cell respiration?

How we extract enrergy from food molecules

What's the formula for cell respiration? Which reactant is being reduced? Oxidized?

C6H12O6 + 6O2 ---> 6H2O + 6CO2 + 38 ATP




-C6H12O6 (glucose) is oxidized & 6O2 (oxygen) is reduced

What are the steps of cell respiration ? Where do they occur?

1) Glycolysis (cytoplasm)


2)Connecter (mitochondrion)


3) Krebs (mitochondrial matrix)


4) ETS (mitochondrial membrane)


5) oxidative phosphorylation (everywhere except outer membrane space)

The final electron acceptor in respiration is

Oxygen (1/2 O2)

The idea of the proton gradient was introduced through the

Mitchell hypothesis

ATP can be made through

Oxidative & substrate phosphorylation

2 ways

Cell respiration can be controlled through

Feedback inhibition

Fermentation occurs when______. Name the two types.

-when no Oxygen present.



Alcohol & lactic acid fermentation.

Which muscle (red or white) is designed for he "sprinters" (I.e. short bursts of activity)

White muscle

What is photosynthesis?

How plants reduce CO2 to make sugars & produce oxygen from water.

What's the equation for photosynthesis? Which reactant is reduced? Oxidized?

6CO2 + 6H2O ------> C6H12O6 + 6O2


sunlight


6CO2 is reduced. 6H2O is oxidized.

Scientist _______ took a willow sappling tree & figured out that the plants weight came from _______

Von Helmont; CO2 & H2O

What are the 2 phases of photosynthesis?

-light-dependent


-light-independent (Calvin)

Photo systems are _________. At the center is a _____ made of _____

Clusters of 200-300 pigment molecules; has a reaction center in the middle that is made of a special chlorophyll a

The light dependent phase is also known as

-the Z-scheme


-non cyclic photophosphorylation

ADP is phosphorylated thru

Chemiosmosis

What is the goal of mitosis?

1 somatic cell gives rise to 2 identical daughter cells

Mitosis is division of the ______.


Cytokinesis is the division of the _______.

Nucleus; cytoplasm

When is DNA replicated?

S phase

Sister chromatids separate & go to opposite poles during

Anaphase

Chromosomes condense into chromatin during

Telophase

The diff between cytokinesis between animal & plant cells is

-animals cells go through cleavage furrow & plant cells form cell plates

Cell division in prokaryotes is called

Binary fission

What is the goal of meiosis?

To produce gametes ( egg& sperm) through cell division

Where can genetic diversity occur?

Prophase I: crossing over


Anaphase I: Independent assortment


Anaphase II: independent assortment


Fertilization

4 places

One primary spermatocyte produces

4 spermatid gametes

One primary oocyte yields

One ovum & 3 polar bodies

Gregor Mendel used _____ to determine_____

Garden pea plants; principles og inheritance

Law of segregation states

When gametes form, they carry one allele for a trait

Law of independent assortment states

Alleles for several traits assort independently when gametes made

Incomplete dominance is when

Neither allele is fully "expressed" in the presence of other allele

Co-dominance is when

Both alleles are fully expressed

Polyenic traits are

when 3 genes affect 1 trait

A karyotype

Examines the physical structure and number of chromosomes

Linked genes

Genes (a) & (b) are on different chromosomes

Recombination frequency equals

The # of recombinant offspring


________________________________ x 100


total number of offspring

Griffith's experiment involved

2 strains of streptococcus & concluded something in the heat killed S strain transformed the living R strain

Hershey & Chase's experiment involved

Virus bacteriophage & e.coli; e.coli went with phosphorus

Chargaff's rule

A=T, C=G

Franklin found that

DNA was a right handed helix

Watson & Crick found

DNA was a double helix

Helicase

Unwinds the DNA helix

Differentiate between DNA poly I & DNA poly III

Polymerase III - adds new nucleotide in 5' > 3' direction



Polymerase I-replaces RNA primers with DNA

Ligase

Seals gaps in okasaki fragments