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48 Cards in this Set

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  • Back
what are the steps in glycolysis
1) With the help of the enzyme Hexokinase ATP phosphorylates (gives its phosphate group) Glucose and becomes ADP-- Glucose
becomes Glucose 6 Phosphate
2) ATP phosphorylates Glucose again to make it more breakable and the Glucose becomes Fructose 1 6 Biphosphate
3) Fructose 1 6 Biphosphate splits into 2 PGAL with the help of the enzyme Aldolase
4) Each PGAL reduces NAD+ and reduces 2ADP (so it makes NADH and 2 ATP which go to the fourth stage) and then each PGAL becomes Pyruvate-- so you end up with 2 molecules of Pyruvic acid
how many ATP do you make in glycolysis
2

you use 2 and you make 4
what does hexokinase do
it is an enzyme that helps ATP phosphorylate glucose the first time
what does aldolase do
it splits the glucose into 2 PGAL
what do you call glucose after it has been phosphorylated twice? (in glycolysis)
Fructose 1 6 Biphosphate
what do you call glucose when it has been phosphorylated once in glycolysis?
Glucose 6 phosphate
what type of ions are absorbed into the mitochondria to power the ATP synthase
Hydrogen
what are the steps to the transition reaction
1) Each Pyruvate gets a CO2 taken away from them (so CO2 is a waste product) and becomes Acetate
2) NAD+ gets reduced by each Acetate and becomes NADH (which goes to the fourth stage)
3) Acetate joins with COA (coenzyme A) and the entire compound is called acetal coenzyme A-- acetal coenzyme A brings the Acetate to the mitochondria
how many ATP will eventually be made from glycolysis (includes NADH made AND ATP made)
8 ATP

- b/c in glycolysis 2 NADH are made and sent to the fourth stage-- each NADH carries 3 ATP-- and 2 ATP are directly made
how many ATP are directly made in the transition reaction
none
how many ATP will eventually be made from the transition reaction
6

- b/c 2 NADH are made and they go to the fourth stage-- each NADH carries 3 ATP
what is the difference between the investment stage in glycolysis and the payoff stage in glycolysis
the investment is when you are using ATP
the payoff is when you are making ATP
what are the steps to the krebs cycle
1) Acetate (2C) joins oxaloacetate (4C) to make Citrate (6C)
2) Citrate gets oxidized by NADP+ and gets decarboxylized (CO2 is getting taken away) and becomes Ketoglutarate (5C)
3) Ketoglutarate gets oxidized by NADP+ and gets decarboxylized and becomes Succinate (4C)
4) Succinate gets dephosphoralated and you make 1ATP in the process-- then it gets oxidized by FAD and becomes Fumarate
5) Fumarate gets oxidized by NAD+ and becomes oxaloacetate and the cycles starts over again
what is the order of the enzymes used in the krebs cycle and how many carbons are in their backbones
Oxaloacetate (4C)
Citrate (6C)
Ketoglutarate (5C)
Succinate (4C)
Fumarate (4C)
Oxaloacetate (4C)
what is the pnumonic for remembering the order of the enzymes in the krebs cycle
only
cool
kids
search
for
oreos
how many ATP are DIRECTLY made in the krebs cycle-- remember the krebs spins twice per glucose
2
how many ATP will EVENTUALLY be made in the krebs cycle-- remember the krebs spins twice per glucose
24

6NADH are made-- so you make 18 ATP
2 FADH are made-- so you make 4
2ATP-- so you make 2

in the end you make 24 ATP which will go to the fourth stage
Glycolysis is what kind of reaction
ANAEROBIC REACTION

doesn't need oxygen to operate
what is the order of cellular respiration
glycolysis
transition reaction
krebs cycle-- aka Citric acid cycle
Electron Transport system
how many ATP are DIRECTLY made in each step
glycolysis- 2
Transition- 0
Krebs- 2
Electron transfer system- 34

=38 ATP
what is an example of an anaerobic process
fermentation-- you don't need oxygen to do it
what is the formula for cellular respiration
C6H12O6 + 6O2----> 6H2O + 6CO2 +ATP
how many ATP does one glucose make
38
which steps happen in the cytoplasm and which steps happen in the mitochondria
cyto-- glycolysis and transition reaction
mito- krebs cycle and electron transfer system
which two coenzymes transport energy (in the form of H ions) from glucose to the mitochondria
FAD
and
NAD
how many ATP are produced from the NADH and the FADH made in the first three steps
22
how many ATP are DIRECLTY produced in the 4th step with no help from the NADH and the FADH and the other ATP made in the first 3 steps
12
how many ATP are directly made from the first three steps
4
how many ATP does FADH hold?
NADH?
FADH- 2
NADH- 3
where does the ETS take place?
in the cristae membrane of the mitochondria
what happens in the ETS
NADH drops electrons off at the first protein complex and FADH drops electrons off at the first mobile carrier

The electrons bounce through the path of proteins- the energy created is used to pump H+ ions and power the ATP synthase (which makes ATP)

At the end of the protein chain the electrons are collected by Oxygen and they make water
at the end of the ETS is oxygen which combines with the electrons to make water.....what is the formula for making water
1/2 O2 + 2e- + 2H+---> H20

half oxygen plus 2 electrons plus 2 hydrogens ---> water
what kind of reaction is the ETS (aerobic or anaerobic) and why?
aerobic!--- b/c at the end of the protein chain is an O2--- without the O2 to absorb the electrons from the chain the system would get backed up and it would not be able to keep running hence no ATP will be made
what is the final electron acceptor in the ETS
oxygen
how many components make up the ETS and what are they
5 components

3 protein complexes
and
2 mobile carriers
what do mobile carriers do
they transport electrons between the complexes
what is chemiosmosis
making ATP with a H+ ion gradient
what pumps the H+ ions in the ETS
the protein complexes
what makes the ATP in the ETS
the ATP synthase
when does fermentation happen?
after glycolysis (since glycolysis is an anaerobic reaction) if there is no oxygen present
what happens in fermentation
1) each pyruvate created in glycolysis reduces NAD and creates NADH
2) The NADH gives its 2H and its 2e- back to pyruvate (pyruvate becomes lactic acid) and the NAD gets sent to power Glycolysis
3) the lactic acid gets sent to the liver where it will get turned back into pyruvate when oxygen is present again
where is the ATP made when fermentation happens and how much ATP is made
FERMENTATION DOESN"T MAKE ANY ATP------- it only makes NADH which is used to power Glycolysis------ITS THE GLYCOLYSIS that makes the ATP (which is 2)-----so if no oxygen is available you are only making 2 ATP (vrs 38)
how efficient is fermentation compared to cellular respiration
2.1% effective
what is one benefit of fermentation
it frees up NAD+ for future Glycolysis use
where does fermentation occur
in the cytoplasm
what are the two types of fermentation and which type do we do?
lactic acid fermentation (we do this one)

and alcoholic fermentation
what happens when too much lactic acid gets built up in a cell
it lowers the PH since Lactic Acid is toxic and the cell will die (since cells only work within a certain PH range)
lactic acid as a little or a lot of energy?
a lot of energy