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31 Cards in this Set

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Function of the lymphatic system

Transport excess fluids away from the intestinal spaces



Transports fats in fluid to the bloodstream



Defend the body against disease

Muscle activity largely influences the movement of lymph via

Action of skeletal muscles



Respiratory movements



Smooth muscle in the larger lymphatic vessels



Valves in the lymphatic vessels

Afferent lymphatic vessels

Carry lymph into a lymph node

Efferent lymphatic vessels

Carry lymph out and away from lymph nodes

Lymph capillaries

Permeable vessels found everywhere but bones, teeth and CNS

Lymphatic vessels/trunks

Collect lymph from capillaries and carries it through body

Right lymphatic duct

Drains right arm, neck and head

Thoracic (L lymphatic) duct

Drains rest of body

Cysterna Chyli

Dilated sack formed by the merging of intestinal and lumbar trunks. "Dilated" to accommodate more fluid

Primary lymphatic organs

Where blood cells become immunocompetent



1) Red bone marrow - primary site



2)thymus gland

Secondary lymphatic organs

Site of most immune responses

Limp nodes


spleen


Lymph nodules

Red bone marrow is the production site of

All blood cells including lymphocytes

Lymphocytes that become immunocompetent in redbone marrow are called

B Lymphocyte cells

Function of thymus

Secretes thymosine


site of T lymphocite maturation

The spleen contains 2 tissue types

White pulp (mostly lymphocytes)


Red Pulp (red blood cells, lymphocytes, macrophages)

Function and location of lymph nodes

Clustered in inguinal, axillary and cervical regions



Act as limp filters = microphages phagocytize



T & B cells destroy microbes by immune response

Describe the connective tissue capsule of lymph nodes

cortex = outter layer that contains B Cells, T Cells and macrophages



Medulla = Contain B cells, macrophages, plasma cells(produce antibodies)



Sinuses = Collect lymph and send to lymphatic vessels

Location and function of Peyer's Patches

Location: Small intestine, the illium.



Function: Surveillance of the intestinal lumen and in facilitating the generation of the immune response within the mucosa

Function of lymph nodules

Remove pathogens from their area

Location of lymph nodules

Tonsils (and adenoids)


Peyer's patch


Appendix

Describe innate immunity

Generic response to a pathogen or foreign substance

Characteristics of adaptive immunity

Antigent specific


Has memory


Systemic (not confined to initial infection site)

What is an antigen

Large complex molecules = usually proteins, may be part of a microorganism

Defense characteristics of innate immunity

Physical defenses = external barrier created through epidermis of skin



chemical defenses = mucus membranes prevent entry of micro organisms

Characteristics of the 2nd line of defense for innate immunity

Anti microbial substances


phagocytes


Inflammation


Fever

Types of specific (adaptive) immunity

Cellular immunity = involves T cells


Humoral immunity = Involves B cells

Types of specialized T cells include

Helper T cells


Cytotoxic T cells


Memory T cells

T cell activation requires 2 signals

1)Antagin-presenting cell : Leaves antigent fragments on surface for T-cell recognition called a marker



2) Costimulator : Chemical signal produced by antigen-presenting sole surface that has been damaged or invaded by pathogens

Humoral immunity limitations

Response limited to body fluids

Humoral immunity produces 2 types of cells

Plasma cells : secrete antibodies



Memory B cells : B lymphocytes left over after eradicating the virus

Antibodies action

Neutralization


agglutination/precipitation


compliment activation