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127 Cards in this Set

  • Front
  • Back

Where is glycogen stored?

Muscles and liver

What does hemoglobin do?

Carries oxygen throughout our body

What type of protein are antibodies?

Globular

Which two protein aid in muscle contractions?

Actin and myosin (both Globular)

What is one difference between DNA and RNA?

RNA has one additional Oxygen

Non-polar molecules, gases, and small molecules move through the phospholipid bilayer by?

Simple diffusion


(Passive transport)

Glucose moves through the phospholipid bilayer via?

Facilitated diffusion


(Passive transport)

What is the difference between simple diffusion and facilitated diffusion?

Facilitated requires transport proteins

What are two types of passive transport?

Simple and Facilitated Diffusion

What are the types of Endocytosis?

Phagocytosis


Receptor-mediated Endocytosis


Pinocytosis

What 3 things do all cells have?

Cell membrane


Cytoplasm


DNA

What is the tangled spread out form of DNA?

Chromatin

DNA condenses into what when it is ready to divide?

Chromosomes

Where are ribosomes created?

Nucleolus

Which organelle makes ATP?

Mitochondria

What helps cells maintain their shape?

Cytoskeleton

What is the cytoskeleton made of?

Microfilaments (Thread-like protein) & Microtubules (thin hollow tubes)

What is going on in cells during interphase?

Growth, DNA replication, and cell functions

What percentage of the cell cycle is made of Mitosis and Interphase?

Mitosis 10%


Interphase 90%

What is the part of chromosomes where the sister chromatids are held together?

Centromere

What is happening during prophase?

Chromosomes are thickening and visible. Nucleus still present in cell

What are the stages of mitosis?

PMAT


Prophase, Metaphase, Anaphase, Telophase

What is happening during Metaphase?

Chromosomes line up in the middle of the cell. The nucleus has been disassembled

What is happening during anaphase?

Chromosomes are moving away to opposite sides via spindles attached to opposite centrioles

What is happening during Telophase?

Chromosomes are at the complete opposite ends. New nuclei are forming at opposite ends and surround the chromosomes

What is responsible for the final separation into two cells during mitosis?

Cytokinesis, splitting the cytoplasm into two cells

The human genome is split into how many pairs of chromosomes?

23

Chromosomes contain a long strand of DNA tightly packaged around what?

Proteins called Histones

After a gene switches on what is attached to the the start of the gene?

Enzyme called RNA polymerase

What is a polyunsaturated fatty acid?

Fatty acid with more than 1 double carbon bond

What is a glycolipid?

Lipid with carbohydrate attached

What is a glycolipid?

Lipid with carbohydrate attached

What is a glycoprotein?

Protein with a carbohydrate attached

What is the purpose of glycolipids?

Act as a marker between cells (mailbox)

What is the purpose of a glycoprotein?

Receptor for signals such as neurotransmitters or hormones

What is the role of cholesterol in the cell membrane?

Maintains its fluidity

Where is cholesterol located within the phospholipid bilayer?

Between the phospholipid tails

What is the function of peripheral membrane protein?

Break down molecules so that they can enter the cell

What is an example of a integral membrane protein?

Channel protein

What kind of protein?

Carrier protein

What kind of protein?

Channel protein

Phospholipids are amphipathic, what does this mean?

They contain both hydrophilic and hydrophobic regions

What are the types of cell connections?

Desmosomes


Gap junctions


Tight junctions

Cell connection that is an anchoring junction found in intercalated discs (skin and heart)

Desmosomes

Cell connection that are openings that let ions pass from 1 cell to the next, found in intercalated discs (heart cells)

Gap junctions

Cell connections that keep space between cells close together (stomach and skin)

Tight junctions

Which cell connection helps keep the integrity of our skin through stress or tugging?

Desmosomes

Which is the tightest cell connection?

Tight junctions

Which cell connection helps keep urine in bladder, making it water tight?

Tight junctions

Which cell connection is known as a communicating junction? Allows ions and small molecules to pass for intercellular communication

Gap junctions

Plasma membrane is selectively permeable. What will it allow to pass through easily?

Lipids (They are non-polar)


Oxygen


Carbon Dioxide


Alcohol

Plasma membrane is selectively permeable. What will need help passing through because they are repelled by the hydrophobic tails?

Glucose, amino acids, electrolytes, and ions

What are the two types of transport across the cell membrane?

Passive Transport


Active Transport

What is osmosis?

Facilitated diffusion of water

What protein is required for transport of water across the cell membrane?

Aquaporin

What are 4 types of passive transport?

Simple Diffusion


Facilitated diffusion


Filtration


Osmosis

What is filtration?

Same as diffusion, but due to hydrostatic pressure. (BP and Glomerular kidney filtration)

What are 4 types of active transport?

Excocytosis


Endocytosis


Phagocytosis


Pinocytosis

Moving a solute that is in a vesicle out of a cell, requires ATP, is called? (Neurotransmitters or waste)

Exocytosis

Moving a solute into a cell by engulfing it into a vesicle, requires ATP, Is called?

Endocytosis

What are two types of Endocytosis?

Phagocytosis


Pinocytosis

What two types of cells move into a cell via phagocytosis?

Macrophages and Neutrophils (WBC)

Cell takes small amount of extra cellular fluid into the cell via?

Pinocytosis

What two forms of transport are known as bulk transport?

Exocytosis and Endocytosis

Sodium potassium pump is what kind of transport?

Active Transport

What is the issue in cystic fibrosis?

Cystic fibrosis transmembrane conductance regulator (integral protein) has in issue transporting Cl- ions out of the cell. These expelled ions attract cations like K+ (resulting in osmosis)

What is the pH of Intercellular fluid?

7.0

What is the pH of extra cellular fluid?

7.4

Composition of solute and solvent is identical to ICF is considered?

Isotonic

Higher concentration of solutes outside of the cell than in ICF is called?

Hypertonic, net water movement is out of the cell. Can cause cell to shrivel

Lower concentration of solutes outside of the cell than in ICF is considered?

Hypotonic, net water movement is in the cell. Can cause cell to burst

What direction does water move within the concentration of solutes?

From low concentration to high concentration

What is the membrane enclosing the nucleus?

Nuclear envelope, protein-lined pores allow material to move in and out

DNA plus associated proteins is called?

Chromatin

What do peroxisomes do?

Metabolize waste

Associated with ribosomes; makes secretory and membrane proteins

Rough endoplasmic reticulum

What does smooth endoplasmic reticulum do?

Makes lipids

What are fibrous proteins that hold organelles in place?

Intermediate filaments

Fibrous proteins; form the cellular cortex

Microfilaments

What is the function of lysosomes?

Digests food and waste materials

What is the function of the Golgi apparatus?

Modifies protein/ lipids. Processes material to be removed from the cell

Which organelle adds sugar to proteins by glyosylation?

Rough ER

Site of protein synthesis

Ribosomes, 2 RNA subunits to wrap around mRNA and start translation

Protein is made in which organelle and modified in which?

Ribosomes


Rough ER

Which organelle synthesizes lipids and steroid hormones, stores Calcium, metabolizes some carbs, and breaks down certain toxins?

Smooth ER

Which organelle sorts, modifies, and ships products from rough ER?

Golgi apparatus

What are 2 examples of the steroid hormones the smooth ER synthesizes?

Testosterone and Estrogen

Which organelle contains enzymes that break down, digest, or destroy foreign materials, toxins, or even dead cells?

Lysosomes

The process of lysosomes releasing enzymes to destroy damaged cells is called?

Autolysis

What is controlled cell death?

Apoptosis

Where is mitochondria more common?

Muscles and nerves

Which organelle contains enzymes to produce H2O2 and convert it to O2 and H2O, this will detoxify the cell? Also plays a role in cell metabolism.

Peroxisome

What are 3 types of Cytoskeleton?

Microtubule


Microfilaments


Intermediate filament

Which cytoskeleton type maintains cell shape, position organelles, and form cilia and flagella?

Microtubules

Which cytoskeleton type consist of actin and myosin in muscles cells for contractions?

Microfilaments

Which cytoskeleton type resists tension on the cell?

Intermediate filaments

What is a difference between microfilaments and Microtubules?

Microfilaments aid with movement within the cell and Microtubules aid with movement outside the cell

Which cytoskeleton type plays a role in the formation of the mitotic spindle?

Microtubules

Peroxisomes are found in abundance in the liver because of their huge role in?

Detoxification

The scarring of the liver is known as?

Cirrhosis

What determines structure and function of a cell?

Nucleous

2 adjacent lipid bilayers that separate the nucleus and the cytoplasm and connects to the ER is called?

Nuclear envelope

What is the regulated pathway for proteins, RNA, and solutes into the Nucleus?

Nuclear pore

Which cells in our body do not have a nucleus?

RBCs, in order to make more room for hemaglobin

Which cells in our body are multi-nucleated?

Skeletal muscle cells (smooth muscle and cardiac muscle cells only have 1)

What are the phases of interphase?

G1, S, G2

During G1, what are cells doing?

Growing

During S phase of interphase, what is happening?

DNA synthesis

What is happening during G2 phase of interphase?

Cells continue to grow and prepare of mitosis

How many chromosomes does the human cell have?

46 chromosomes (up to 92 chromatids)

What are homologous chromosomes?

One set of chromosomes from each parent

What are the roles of the mitotic spindle during mitosis?

Prophase - starts to form


Metaphase- starts to attach to chromosomes


Anaphase- shortens


Telophase- breaks apart

What is cyclin?

Checkpoint in cell division

When does the cell reach checkpoints in cell division?

End of G1, end of G2, and end of Mitosis before cytokinesis.

Where does transcription in DNA synthesis happen?

Nucleus

Where does translation in DNA synthesis happen?

Cytoplasm

Translation is the process of creating?

A chain of amino acids (polypeptide)

What is responsible for bringing anticodons during DNA synthesis?

tRNA

Unspecialized cells, divide without limit

Stem cells

Unspecialized cells, divide without limit

Stem cells

What are Totipotent cells?

Can become anything

What are pluripotent cells?

Can become any human tissue cell

What are multipotent cells?

Can differentiate within a certain cell lineage (ectoderm, mesoderm, or endoderm)

What are oligopotent cells?

Can become 1 of a few different cell types

What are untipotent cells?

Can only make more of its own cell type

What type of cell is fully specialized?

Unipotent

What is the difference between lysosomes and peroxisomes?

Lysosomes are responsible for the intercellular digestion of cells and peroxisomes are responsible for the protection of cells against toxins (peroxide)