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20 Cards in this Set

  • Front
  • Back

Endocrine system

Ductless glands with endocrine tissues within other organs


Secret hormones into blood


Act on target cells

Hormones classes

1. Steroids - from cholesterol


(Testosterone, vitamin D)


2. Hormones derived from amino acids


3. Peptides and protein hormones

Hormones derived from tyrosine

1. Thyroxine/T4


(Lipid soluble controls cellular metabolism, growth, development)


2. Epinephrine and norepinephrine


(Adrenal medulla hormones, short term stress/flight or fight)

Peptides and proteins hormones

Chains of amino acids held together by peptide bones


Water soluble


E.g. oxytocin, ADH, GH, insulin

Pituitary gland

Suspended from hypothalamus


Lies in sella Lucia of sphenoid bone


2 lobs (anterior and posterior

Anterior pituitary

Epithelial tissue


Regulated by hypothalamus


Produces metabolism and reproduction hormones

Metabolism hormones released by anterior pituitary

1. Growth hormone


2. Thyroid stimulating hormone


3. Adrenocorticotropic Hormon


(Stimulates secretion of adrenal steroids)

Reproduction hormones from anterior pituitary

1. Luteinizing Hormone (LH)


2. Follicle stimulating Hormon


3. Prolactin (stimulate milk formation)

Posterior pituitary

Nervous tissue


Extension of hypothalamus


Secret and store Hormones from hypothalamus


Hormones secrete/stored from posterior pituitary

1.Oxytocin (stimulates uterine contraction and milk ejection)


2. Antidiuretic hormone (water reabsorption in the kidney)

Thyroid gland

On anterior surface of superior part of trachea


Butterfly shape

Thyroid gland histology

1. Follicles


-wall=epithelial cells


- produce T4



2. Parafollicular cells


-between follicles


-secret calcitonin

Calcitonin

Increase Ca uptake into bone (increase bone growth)


Lowers Ca in blood

Parathyroid gland

4 glands embedded in posterior thyroid


Secret parathyroid hormone

Parathyroid hormone

1. Increase Ca released from bone


(Activates osteoclasts)



2. Decress Ca loss in urine



3.increase Vit. D activation


(Vit. D increases Ca absorption at the small intestine)

Adrenal glands 2 main parts

Superior surface of each kidney


1. Adrenal cortex (epithelial tissue & secret steroids ONLY)



2. adrenal medulla (nervous tissue)

Adrenal cortext 3 layers

1. Zona glomerulus - secrets minalocoricoids (salt balance)



2. Zona fasciculate -secrets glucocorticoids (long term stress)



3. Zona reticularis - secrets androgens and small amount of testosterone (sex drive and converted to estrogen in fat)

Pancreatic islets of langerhans

A cells - produce glucagon (increase blood glucose)


B cells - produce insulin (decress blood glucose

Hypoyhalamus

Regulates anterior pituitary via


GH releasing hormone


GH release inhibiting hormone


GnRH gonadotropin releasing hormone (LH, FSH)



Synthesizes posterior pituitary hormones

Gonads hormones

Leydig cells - testosterone



Cells of 1° & 2° follicle - estrogen


Corpus lutein - estrogen and progesterone