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66 Cards in this Set

  • Front
  • Back
What are the characteristics of cancer cells?
Larger than normal cells
Bigger Nucleus
Little resemblance to normal cells
Varying size and shape (not uniform)
Grow rapidly
Respect no rules for growth or division
No purpose or function
Exist only as parasites
Require nutrition
May be liquid or solid
What are the difference in grading of cancer cells?
Grade 1: cells resemble normal cells (best prognosis)
Grade 4: cells look nothing like the host tissue (malignancy)
What is Carcinoma?
cancers which arise from epithelial tissues (skin, mucous membranes, glands)
What is Sarcoma?
Cancers which arise from blood vessels, lymph nodes, nerves, connective tissues, muscle or bone
How do you stage cancer?
T: characteristics and the size of the Tumor
N: involvement of lymph Nodes
M: metastasis (spread to the distant organs)
What are the cancer diagnostic tests?
Imaging (X-ray, CT scan, MRI)
Biopsy (closed with needle)
Blood Tests (CA-125 ovarian, PSA)
Physical Exam
PET scans
What are the objectives of cancer treatment?
Cure
Control
Palliation
Adjuvant therapy (combining therapy - yoga, herbs, chemo)
What are the types of surgical treatment of cancer?
Biopsy
Tumor and Lymph node removal
De-bulking
Hormone Ablation
Surgical Palliation
Staging Laparotomy
Reconstruction
How is hormone ablation helpful in breast cancer?
Younger females with breast cancer have a more difficult illness because they have more estrogen to feed it - hormone ablation helps that
How does external radiation work?
its a condensed beam of radiation that is pointed towards the tumor, but doesn't make the pt radio active
How does radiation work?
it stops cell division and breaks bonds
What is the nursing care for patients receiving internal radiation?
Limit time in the room
Maintain distance from pt
Shield yourself from radiation
Wear dosimeter
never handle implant
Handle secretions/excretions with gloves
dispose of dishes and silverware
Give lots of eye contact and conversations from doorway
administer laxatives before treatment begins
observe the skin for breakdown
provide divisional activities
What are precautions for family members when they visit?
Stay 30mins and 6 ft away
Must not be pregnant
Must have paper shoe covers, gowns and gloves
Encourage family members to make frequent telephone calls
How does chemotherapy work?
combination of drugs promotes cell death by disrupting the cell life cycle so they can't reproduce

targets fast growing cells
What are some fast growing cells?
Hair
GI
WBC

chemo attacks these because they have more cycles to attack
What are some nursing implications for administering chemotherapy?
Must be certified
Protective gloves and aprons must be worn (even 48hrs after chemo has stopped)
Special disposal of tubing, bags, etc
Special procedure for cleaning spills
Why are chemo pts more susceptible to infection?
because WBC grow fast and are destroyed
Occurs at the nadir (7-10 days after initiation)
Absolute Granulocyte Count Decreases (<1000 BAD)
What are the neutropenic precautions?
Handwashing **
No crowds or small children
Avoid sunburn (heals slowly)
No dental work or invasive procedure
No tampons, foleys, or rectal temperatures
Take T frequently (>100.4 bad)
No plants, standing water, or fresh or uncooked foods
Wear mask ambulating in halls
Neupogen injections to stimulate WBC growths (WBC <500)
? Cantelope?
What can you do if a cancer patient has a fever?
Sponge bath
Ice packs
cooling blanket
Tylenol
No ASA or ibprofen
What are the Thrombocytopenia precautions?
<50,000 platelets

Use soft toothbrushes
No IM injections
Give stool softeners or laxitives
Apply pressure for 5 mins to injury
Hemoccult test
Progesterone used to stop periods
Give platelet transfusions (<20,000)
Assess for petechiae, bleeding from nose, urine, or in mouth
Administer Neumega (promotes RBC growth)
What are some education points for pts with anemia getting chemo?
Plan rest periods
Avoid sudden position changes
Increase iron intake
Transfuse when pt is symptomatic <11
Report CP, dyspnea, SOB, dizziness, inc HR
What are some GI S/E of chemo and radiation?
Anorexia (give nutrient rich food)
Stomatitis (magic mouth wash)
N/V (avoid smelly foods)
Diarrhea (fluid, BRAT diet, full bladder during radiation)
Constipation (esp with Vinca-Alkaloid Rx)
How do you treat stomatitis?
Magic Mouth wash - avoid citrus foods
Niastatin, Karafate, Lidocane

sometimes yeast will grow from Tx
How do you treat N/V?
prevention
Give Zofran, Decadron, and Benadryl
What are other S/E of Chemo and Radiation?
Alopecia
Renal Dysfx (hydrate to prevent)
Fatigue, depression, hopelessness
Gout (Rx alpurinol)
Don't use steroids - delays healing
To prevent renal dysfunction in chemo and radiation, when would you hold chemo?
if BUN and Cr are increased or WBC are decreased

use lasix and mannitol to tx
What happens if the cancer is in the brain, and the pt needs chemo?
because it can't cross the BBB, you can put it in the spinal fluid
What are the Oncologic Emergencies?
Superior Vena Cava Syndrome
Spinal cord compression
Hypercalcemia
Pericardial Effusion
Extravasation
What are the S/S and Tx for Superior Vena Cava Syndrome?
S/S: tumor causing Venous blood backing up - SOB, facial edema, JVD

Tx: notify the Dr., elevate HOB, O2
What are the S/S and Tx for Spinal Cord Compression?
S/S: sudden loss of bowels and bladder control, can't feel legs

Tx: pain management, avoid valsalva, surgery
What are the S/S and Tx for Hypercalcemia?
S/S: >12 Ca, ECG changes, N/V

Tx: Hydration and lasix
What is important to know about prostate cancer?
Risk factors: none except age
S/S: difficulty urinating
Diagnostic Tests: PSA
Treatment: surgery, radiation and chemo
Nursing: edu about catheters
What is important to know about Laryngeal cancer?
Risks: Tobacco and ETOH
S/S: hoarseness w/o bad cold
Diagnosis: laryngoscope, Xray, biopsy
Treatment: internal or external radiation and/or surgery to remove larynx
Nursing: airway management, trach education (pt sit up, more sputum, expect bloody drainage, can't speak)
What is lymphoma?
a group of malignant diseases having thier origin in the lymphatic system and can spread to the other lymphatic tissue

Hodgkins and non Hodgkins
What age frequently gets Hodgkins and Non Hodgkins?
Hodgkins: 15-35 and over 50

Non-Hodgkins: children age 5 or >35
What is thought to be the cause of Hodgkin's Lymphoma?
immunodeficiencies or viral agents
What are the S/S of Hodgkin's Lymphoma?
Begins in lymph close to large vessels occurring OVER NIGHT
Painless lump swelling first sign
Night Sweats, itching, and low grade fever
Lymphocyte function makes pt susceptible to infection
Lumps might compress internal organs
What are the S/S of Non-Hodgkins Lymphoma?
Abnormal malignant lymphocytes proliferate in the lymph nodes and spread (HIV susceptible)

Lymph is LARGE throughout the body
How is Hodgkin's Treated?
Stage 1&2: high dose radiation (above diaphragm)
Stage 3&4: Chemo and radiation (below diaphragm)

good prognosis 90% survival
How is Hodgkins diagnosed?
Presence of Reed-Sternberg Cells

Staged according to the spread of the disease (1 is single location)
What is Multiple Myeloma?
Cancer of the bone marrow where abnormal plasma cells proliferate

these cells destroy bone marrow dec RBC WBC and platelets
What are the S/S of Multiple Myeloma?
Bone pain from pressure
Because Ca is pushed out of the cells - fractures
Hypercalcemia (Tx with hydration)
Kidney Failure
What is the treatment for Multiple Myeloma?
No Cure, but can be controlled
Bone Marrow transplant
What is a risk factor for Pancreatic cancer?
smoking
What are the S/S of Pancreatic Cancer?
Abdominal Pain
Weight Loss
Jaundice
DM if tumor is removed from the head of pancreas
What is a treatment option for Pancreatic Cancer?
Whipple Procedure

removal of the head of the pancreas, gallbladder, distal stomach, and duodenum

the remaining pancreas and stomach are attached to the jejunum allowing bile to flow and relieve jaundice
Why is the Whipple Procedure risky?
because the suture lines may erode from the pancreatic enzymes
What information is important about Bladder Cancer?
Risk: smoking
S/S: painless hematuria, may go through the inside lining of the bladder or cancer may go through the thickness of bladder wall
Tx: partial or total cystectomy
What are the risk factors for Colon/Rectal Cancer?
Smoking
Alcohol
Obesity
Red Meat
Low Bulk and Low fiber diets

ASA and exercise can dec risk
How does Colon/Rectal Cancer spread?
seeding through the regional lymph nodes and by vascular invasion via portal vein (lungs and liver)
What are the S/S of Colon/Rectal Cancer?
Bloody Stool (Hematochezia)
Black tarry stools (Melena)
Mucous in Stool
Diarrhea
Abdominal Pain
Weight Loss
How is Colon/Cancer Diagnosed and Treated?
Colonoscopy and Biopsy

Tx: colon resection, radiation, and chemo

might have colostomy after surgery
What is the treatment for Testicular Cancer?
Radical Orchiectomy
Chemo and radiation might be done if theres metastasis
What are the risk factors for Breast Cancer?
Family Hx
>30 when having first child
Nulliparus
>50

but 80% don't have any risk factors
How do you detect breast cancer and testicular cancer?
self examination

mammograms recommended yearly
What are the S/S of breast cancer?
Slow forming tumors
Non-tender
Movable
Usually in Upper outer quadrant
Dimpling (like skin of orange)
Asymmetry
Nipple retraction
Ulceration (late sign)
What are the surgical procedures for breast cancer?
Lumpectomy
Partial Mastectomy
Simple Mastectomy (skin and soft tissue remain)
Modified Radical Mastectomy (muscles remain)
Radical Mastectomy (Everything gone)
What is the nursing care after breast cancer surgery?
Hemovac or Jackson Pratt tubes for drainage
Bulky dressings on surgical site
Elevate arm to prevent lymphedema
Pain control so pt can cough turn deep breathe
What should you educate the pt after breast surgery?
Wash cuts and scratches promptly
Electric razor only when shaving underarms
Do not carry purse on affected side
No BP or needle stick on affected arm
Wear gloves when gardening
Reach for Recovery program
Emotional support
ROM after 3 days
What is leukemia?
diseases of the blood forming systems, characterized by abnormal proliferation and maturation of certain leukocytes (in bone marrow, spleen, liver, lymph nodes)
What are the levels of WBC in leukemia?
Inc WBC but very immature and can't function

the large number of WBC squeeze out and destroy platelet and RBC making the pt anemic, hemorrhage, and susceptible to infection
What are the S/S of leukemia?
Bleeding (nose bleeds common in children)
Bruising
Anemia
Fatigue
Infection
Fever (no ASA)
Bone Pain


fatal within 3 months if aggressive chemo isn't started
What is the treatment like for Leukemia?
Chemo, radiation, and sometimes bone marrow transplant

Introduction Chemo - high dose of chemo intended to kill most of the leukemic cells (hospitilized 4-6weeks)

Consolidation Chemo - given 6-8 months after to assure success (out pt)

Neutropenic precaution
What is important to remember about families with cancer?
family members all grieve in different ways on different schedules

it is common for the pt to accept diagnosis before family

Hope is the most powerful emotion
What is hospice?
at home or in pt care for pts with terminal illnesses (expected life span <6months)
What are the goals of hospice?
comfort of the pt
helping family be with the dying one
care for the family after pt death

Physical, emotional, and spiritual support are given through a combination of professional and volunteer services