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What Role Does Blood Play In Distribution Of Lead

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To start we will be looking at blood’s role in distribution of lead. Blood plays a major role in the distribution of lead even though it has a tendency to carry a small fraction of the total amount of lead present in a body. This is due to the fact that blood is constantly circulating and coming into contact every single part of the human body. Lead found within the blood system on average has a half life nearing only 1 month. Next is distribution and storage through the accumulation of many soft tissues. Lead storage seen within soft tissues has a tendency to have higher concentration when a acute exposure has occurred to the individual. Lead is able to move swiftly in and out of soft tissues, while bones may store lead for a long time period. The soft tissues that are significantly associated with this distribution of lead are the liver, lungs, and kidneys as well as the brain.(ATSDR2005) Lead found within soft tissues has a potential half life of nearly 40 days. …show more content…
Lead that is stored within mineralizing tissues is not uniformly distributed. Bone is divided into two compartments. One is the trabecular bone, or shallow region. The trabecular component of bone is where the most bone stored lead to systemic redistribution takes occurs. Lead in that bone region has a half-life of nearly 90 days. Cortical bone, in comparison, may have a half life of a decade and up to 30 years. Bone to blood distribution increases in times of stress, fractures, calcium deficiency and hyperthyroidism due to deterioration of these mineralizing

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