S. aureus is a commensal bacterium of the human body asymptomatically colonizing in twenty-five percent healthy individuals. (Kriegeskorte& Peters, 2012; Lindsay, 2013). The predominant niche for S. aureus in humans is the vestibulum nasi (anterior nares) which are the nostrils of the nose. The anterior nares are considered the primary source of inoculation of other body sites (skin, throat, armpit, groin, and gut) through hand transfer and it increase the risk of nosocomial infections. The reason behind S. aureus thriving in the nasal area and skin is because of its ability to form firm interactions with the host’s moist squamous or ciliated epithelium cells to prevent their elimination by nonspecific immune defenses such as the mucous the membrane. The firm interactions between S. aureus and its host is mainly dictated by specific interactions between adhesions on the bacterial cell wall and their target ligand on the host’s cells.
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aureus depends upon to establish a suitable niche in the nasal area and the most essential determinants are: microbial surface components recognizing adhesive matrix molecules (MSCRAMMs), wall teichoic acid (WTA), and S. aureus clumping factor
aureus depends upon to establish a suitable niche in the nasal area and the most essential determinants are: microbial surface components recognizing adhesive matrix molecules (MSCRAMMs), wall teichoic acid (WTA), and S. aureus clumping factor