Subarachnoid Hemorrhage Research Paper

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Introduction
Stroke is considered as a common cause of mortality and morbidity in the world. 1,2,3 In addition, it has 2 major subtypes, hemorrhagic and ischemic stroke. The ischemic stroke is the commonest followed by subarachnoid, intraventricular and intracerebral hemorrhages. 1,4,5,6,7 According to the literature, the incidence of subarachnoid hemorrhage is 25 to 30%. 1 Treatment in the form of endovascular coil embolization or clipping is performed to decrease the risk of death. 1 Nevertheless, few effective treatment options are available nowadays that can minimize the neurological deterioration and white matter injury caused by the subarachnoid hemorrhage. In addition, the understanding of the mechanism of white matter injury after stroke
…show more content…
1,8,9 Moreover, standard brain magnetic resonance imaging can show, in great detail, the deeper and superficial brain parenchymal structures. Furthermore, several specialized sequences have been developed to elucidate the normal physiology of axonal and neuronal functions. Diffusion tensor imaging or diffusion tensor tractography is one of those sequences. 1 In addition, it can show the integrity and directionality of the axonal fibers and the changes in neuronal tracts after subarachnoid hemorrhage. …show more content…
Filler et al. in 1991, obtained the first tractography images that demonstrated the multi-dimensional data of white matter tracts. Additionally, the clear descriptions on imaging a group of patients were submitted and published in 1993 in the World Intellectual Property Organization. 8 Furthermore, in 1992 at medicine annual meeting in Berlin, the first diffusion tensor images were published in the proceedings of the Society for Magnetic Resonance. 7,8
On the other hand, before 1992, there was a strong belief, among the clinical community, that the application of diffusion magnetic resonance imaging to trace brain neuronal tracts was not possible. However, in late 1991, Filler, Howe and Richards demonstrated the feasibility to produce the linear neural images of the neural tracts using diffusion magnetic resonance imaging. After, in 1992, it was reaffirmed by other researchers (LeBihan and Basser in Bethesda).

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