Spontaneous Differentiation And Differentiation In Stem Cells

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Stem cells are very homogenous due to the fact that they are of the same family type or lineage characteristically speaking. They are differentiated from other cells by two features. The first feature is that they are able to divide by cell division and the second feature is that under specific experimental conditions they can be directed to become tissue cells with certain functions.
Stem cells are able to transform or regenerate themselves growing into the body’s approximately 200 different cell types. Most of the time stem cells would regenerate into the specific cell of the tissue the stem cell is situated although they are still able to take the form of any type of cell. This occurs only under specific conditions. Stem cells
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Scientists are still unsure on what signals activates the differentiation procedure.
Spontaneous differentiation occurs when embryonic stem cells stick together to create embryoid bodies therefore this allows the embryonic stem cells to take the state of a variety of stem cells.
Spontaneous differentiation may be an efficient way to indicate whether an embryonic stem cell is healthy although it is not an effective way. Spontaneous differentiation is also not effective as it is not controlled therefore to produce specific cell types scientists try to control the differentiation process of embryonic cells in order to do this. They do this by either altering the culture medium by changing the chemical composition, modifying the culture dish’s surface or injecting specific genes within the cells.
The process of growing cells within the laboratory is called ‘cell
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This layer is known as the ‘feeder layer’ although now researchers have developed methods to create embryonic stem cells without the need of the mice cells due to the fact that there is a risk of viruses and macromolecules within the mice cells that could potentially be transferred to the human cells.
Embryonic stem cells which have been proliferating within cell culture for an extended period of time without differentiating, (turning into another cell type), and are pluripotent are called embryonic stem cell lines.
Throughout the process of developing embryonic stem cell lines, there is a process that is run called ‘characterisation’ to check whether the cells show the essential properties that are needed for them to be definitely be embryonic stem cells although this is one of the many tests that must be

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