Putting Madness in Its Place: Can the Environment Explain Schizophrenia’s Hereditary Patterns? Schizophrenia is a condition that have symptoms like hallucinations and disorganized thoughts; it does not have clear biological markers. One percent of the general population will be diagnosed with schizophrenia, but an offspring of a schizophrenic parent will have the odds jump to about one in 10. Schizophrenia is heritable, but its genetic underpinnings have not been discovered yet. There has been an attempt to find its heritability conducted by three crack teams of investigators that pooled genomic data from eight thousand schizophrenics of European ancestry. …show more content…
For example, between identical twins, it is possible that one twin has schizophrenia while the other does not. I cannot say much about the correlation with the disease with geography because I believe in the statistics. Although, I can say that no one knows their entire heritage and blood line, so I believe that basing the heritability of schizophrenia on the amount of people of the same ethnicity can be very difficult. I believe that one factor for schizophrenia is how one was raised and their personality. I came to this conclusion because statistics say that there are no affected at 0-2 years of age, but there are at 3-5 years of age. I do agree that a combination of genetics, environment, and alter rain chemistry and structure may play a role. I think how schizophrenics were raised could be a cause because from a young age, children learn from their environment and their environment also plays a role in molding their personality and character. Overall, I believe that the idea which environment, like their geography, having the possibility of playing a role in schizophrenia is not easily …show more content…
“Dimmer switches” control the level of protein created from a given gene, and may regulate the development, function, and the life span of cells that begin to vanish from the brain at the onset of Parkinson’s disease. Parkinson’s affects an estimated 500 thousand Americas, and is a debilitating illness of unknown origin. It is characterized by tremors the deterioration of motor ability, and stiff movements. It is believed that it is jump-started by a loss of neurons in the substanita nigra, a midbrain region. The cells are killed in the course of the disease and are linked to movement control. They produced a neurotransmitter, which is dopamine. Dopamine is required to be able to communication with other neurotransmitters and with cells in different brain areas. Genes can be determined to be active or dormant at a particular time because some proteins act as transcription factors, and basically act as light switches for genetics. However, microRNAs, which are short segments of RNA that has been coded by the genome, are like dimmer switches. There was an experience with mice that made them reminiscent of Parkinson’s disease, complete with a loss of dopamine. The mice that experienced these were mutated mice that lacks the ability to make one of the two enzymes in their midbrain. Scientists have also examined postmortem brains of Parkinson’s patients