Sarcopenia Case Studies

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AIM: Sarcopenia has been defined as an involuntary loss of skeletal muscle mass and strength and/or function. The presence of sarcopenia in patients with Parkinson’s disease (PD) may have prognostic effects and may be mistaken for poor therapeutic control of PD.
We aimed to evaluate sarcopenia in patients with PD.
METHODS: One hundred non-demented PD patients, and 95 healthy subjects were included in the study. Avarage-Muscle mass, weight, bone mass, fat mass, basal metabolism rate (BMR), body mass index (BMI) of PD and control groups were measured using bioimpedance analysis.
RESULTS: There were statistically significant difference in average muscle mass of men and women in PD and control groups, 29,83±2,13kg/m2 and 31,96±1,66kg/m2,(p=0,000), and 25,43±2,16kg/m2 and 26,82±1,69kg/m2(p=0,002), respectively. There were statistically significant difference between weight, fat mass, bone mass, BMR and BMI in men in PD and control groups, 76,47±11,71 and 82,64±11,08 (p=0,005); 18,32±6,13 and 21,55±7,84 (p=0,01); 2,91±0,37 and 3,04±0,27 (p=0,03); 1679±236 and 1775±179 (p=0,01); 27,40±3,58 and 28,88±3,52 (p=0,02), respectively. In women there were statistically significant difference between
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26,27 The prevalences of sarcopenia in nursing home residents were found in 3 Turkish studies as 85%, 68%, and 38,9%. 7,28,29] Until now, there is no documented prevalence of sarcopenia in PD and little is known about body composition in PD. In our study we compared age matched PD and healthy control group living in the community. The mean age of our subjects in both groups were over 60 years old. So in our study, both of our groups have the risk of sarcopenia because of their ages and we found statistically significant difference between FFM of men and women in both PD and control groups (p=0,000 and p=0,002; respectively). This result showed that PD could increase the risk of

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