Krabbe Leukodystrophy Research Paper

For my essay I choose to write about rare genetic diseases from the nervous and skeletal systems. Though different systems, the nervous and skeletal system communicate well between each other. The skeletal system consist of all the bones in the body. The vertebrae and skull, both major parts of the skeletal system, house the 2 main structures of the nervous system: the spinal cord and brain. The vertebrae protects the spinal cord from injury while the skull protects the brain. Now what would happen if the brain, being the organ that controls the entire body and its function, would suddenly allow toxic build up in the brain? It would become deficient and create demyelination ultimately infecting the nervous system to become Krabbe Leukodystrophy.

First discovered by …show more content…
When the disease’s systems are seen before, a treatment called Stem Cell Transplantation or HSCT can help stimulates normal development of myelin and reduces neurological symptoms. But after the disease is onset, it's a matter of making the child comfortable until the disease has taken over.

Though our next disease only connects by the facts that it and Krabbe Leukodystrophy are both genetic and are not seen differently in genders, Osteogenesis Imperfecta is definitely something to look into. Osteogenesis Imperfecta is to have been known since the time of the pharaohs and Vikings! But it wasn't till the 1840’s that the term “osteogenesis imperfecta” was used in medical literature.

Osteogenesis Imperfecta is a genetic disorder where the bones are so sensitive that they break from either little or no apparent causes. It is possible to diagnose Osteogenesis Imperfecta or OI merely on clinical features but that's not always the case. To help confirm some diagnosis, clinical genetics go as far to perform biochemical (collagen) or molecular (DNA) tests. Even