Hemolytic Anemia Case Studies

Improved Essays
This clinical case involves a blood disorder called the autoimmune hemolytic anemia. This disorder occurs when the body immune system malfunctions and makes antibodies that act against the cells. What could cause the body’s immune system to turn against its own red blood cells? Sometimes the cause is unknown, but at times the destruction occurs for no known reason within the autoimmune hemolytic anemia disorder. The disorder is also called idiopathic autoimmune hemolytic anemia since the exact cause of this disease cannot be determined and it is the primary disease. Autoimmune hemolytic anemia also can become secondary to another disease, such as lupus and develop in association with the disease. An autoimmune disease is caused by antibodies produced against substances naturally present in the body. Hemolytic is a phrase relating to the destruction of red blood cells, and anemia is a condition marked by insufficiency of red blood cells or of hemoglobin in the blood. Within autoimmune hemolytic anemia, the red blood cells are being destroyed faster than they are being replaced by the red bone marrow. Also, the malfunction in the immune system involves substances that are produced within the body that causes its own corpse to destroy red blood cells as if they were substances foreign to the body, resulting …show more content…
In the cold autoimmune hemolytic anemia type, the antoantibodies become most active and attack red blood cells only at temperatures well below normal body temperature. Warm antibody autoimmune hemolytic anemia types are more common because IgG autoantibodies are involved in this disorder which reacts best with red blood cells at 37°C. The autoantibodies attach to and destroy red blood cells at a temperature equal to or above the normal body temperatures. By being able to determine which type of anemia a patient has, can determine the best treatment for the

Related Documents

  • Improved Essays

    A. S AKI Case Study

    • 796 Words
    • 4 Pages

    point) Interpret A.S.’s laboratory test results and describe their significance to the patient’s disease process. Both the Hemoglobin and hematocrit are low which can be a sign of kidney failure. When the kidneys start to fail the amount of erythopoietin being relased c often times decreases and the erythopoietin is what stimulates the red bloos cell production. WBC’s are on the low side but still within normal range.…

    • 796 Words
    • 4 Pages
    Improved Essays
  • Improved Essays

    Production of alloantibodies are antibodies against foreign red blood cells which arise from transfusions and result in an alloimmune haemolytic anaemia [3]. Autoimmune haemolytic anaemia results in the production of antibodies against the patient's own red blood cells [3]. Figure 3: Diagram taken from https://imagebank.hematology.org/image/60307/schistocytes--triangulocytes-and-helmet­ cells. This shows an autoimmune haemolytic anaemia, with spherocytes and polychromasia. 6.…

    • 2289 Words
    • 10 Pages
    Improved Essays
  • Improved Essays

    Case Study 1: 1.The most likely cause of the ABO typing discrepancy in the reverse type is due to “unexpected antibodies” such as a cold/room temperature reacting alloantibody. 2.Since the auto control didn’t agglutinate, an alloantibody is suspected. With that being said, it needs to be one that reacts at room temperature. Furthermore, based on the antigen typing of the patient P1 is suspected to be interfering with the ABO results. The Lewis antigen was ruled out due to it being present on the patient’s RBCs.…

    • 1184 Words
    • 5 Pages
    Improved Essays
  • Improved Essays

    APA Summary Paper

    • 412 Words
    • 2 Pages

    Past Medical & Surgical History, Pathophysiology of medical diagnoses (with APA citations) 1. Iron Deficiency Anemia: The most commonly occuring cause of anemia. Iron deficiency results in the lack of iron for hemoglobin synthesis within the body. This may be a result of low intake, diminished absorption, physiological increase in requirements, excessive iron loss, chronic renal failure, hemodyalisis, and idiopathic iron loss.…

    • 412 Words
    • 2 Pages
    Improved Essays
  • Improved Essays

    “A hemolytic transfusion reaction is a serious complication that can occur after a blood transfusion. The reaction occurs when the red blood cells that were given during the transfusion are destroyed by the person 's immune system” (Transfusion reaction - hemolytic,…

    • 1240 Words
    • 5 Pages
    Improved Essays
  • Superior Essays

    1. A 35-year-old male has come to see you because he is urinating, by his estimate, about 8L/day. He is constantly thirsty and drinks as much cold water as he can every day. His sleep is disrupted because of the need to urinate throughout the night. During your assessment, you learn he had several concussions playing college sports.…

    • 880 Words
    • 4 Pages
    Superior Essays
  • Brilliant Essays

    (2009). Drug-induced immune hemolytic anemia. ASH Education Book, 1, 73-79. doi: 10.1182/asheducation-2009.1.73 Garrison, C. (2009). Iron disorders institute guide to anemia.…

    • 246 Words
    • 1 Pages
    Brilliant Essays
  • Improved Essays

    Among other things, CBC test shows how many current red blood cells and the hemoglobin is present, and will assess the size and shape of red blood cells present. Treatment: Sickle cell disease usually requires a long treatment, treatment includes: The usual clinical course for the disease in which both extra & intravascular hemolysis present with anemia (well tolerated) can be treated with:- A) Dose of 5 mg folic acid daily to overcome the folate loss due to continuous beak down of RBC.…

    • 1041 Words
    • 5 Pages
    Improved Essays
  • Decent Essays

    When manifestation of acute hemolytic reaction appear the nurse should immediately stop the transfusion process, maintain venous access with physiological saline, measure vital signs and call for urgent medical support, after that the nurse should rapidly inform the transfusion laboratory urgently and seek early support from critical care and hematology teams to admit the patient to an intensive care unit if possible. Also, nurse should give antihistaminic medications according to doctor order, after managing the case incident report should be done, (Napolitano et al…

    • 85 Words
    • 1 Pages
    Decent Essays
  • Improved Essays

    As the cells are destroyed, the part of red blood cells that carries oxygen, hemoglobin, is released into the blood and passed in the urine. (Medline) Characterized by the premature destruction of healthy red blood cells by autoantibodies, Paroxysmal cold hemoglobinuria is a rare type of anemia.…

    • 1816 Words
    • 8 Pages
    Improved Essays
  • Improved Essays

    This condition may cause part of the red blood cells (hemoglobin) to appear in the urine, making the urine red (hematuria). In most cases, the body can make enough new red blood cells to replace the damaged cells. If the body cannot replace red blood cells quickly enough, the blood will not carry enough oxygen throughout the body (anemia). This can cause fatigue and weakness.…

    • 558 Words
    • 3 Pages
    Improved Essays
  • Great Essays

    Sickle Cell Anemia is a blood disorder that causes red blood cells to become misshapen and not live as long as a regular blood cell. This sickness is a genetic…

    • 749 Words
    • 3 Pages
    Great Essays
  • Superior Essays

    Fever is due to the leukemia cell infestation in the bone marrow and blood stream. Regular blood cells created from hematopoiesis are able to aid the body in fighting off infections, but with the leukemia cells this is not the case. They are incapable off fighting off infections, which is why fever is usually present. Since the hematopoiesis is off red blood cell levels are lower than usual. Red blood cells are what the human body uses to receive oxygen and energy.…

    • 1167 Words
    • 5 Pages
    Superior Essays
  • Improved Essays

    Sickle cell anemia is a genetic blood disorder that causes normal red blood cells to form into an irregular shape, called sickled-cells. The sickle cell gene causes the body to produce abnormal hemoglobin. After a while, the hemoglobin will then cluster together anywhere in the body causing the blockage of blood flow through the blood vessels. This blockage deprives the tissues and blood of oxygen which can lead to many difficulties and problems. SCD becomes life-threatening when the damaged red blood cells begin to breakdown, when the spleen does not work properly or at all, or when it is unable to prevent infections from coming in.…

    • 1506 Words
    • 7 Pages
    Improved Essays
  • Superior Essays

    If anemia is severe, it is treated by medical procedures like blood transfusion. The blood donor and recipient blood ought to match and be given through an IV line into a blood vessel. Blood and bone marrow stem cell transplants replace the faulty stem with a healthy one from a healthy donor. Surgery is done when there's a life-threatening bleeding inflicting anemia. For an example, an enlarged or diseased liver will cause…

    • 1187 Words
    • 5 Pages
    • 4 Works Cited
    Superior Essays