Central Nervous System Analysis

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In neuronal development, the general rule is that cells are generated in sites different from those they later reside in. The Nervous System is the master controlling and communicating system of the body. Electrical impulses act as signaling device; they are rapid, specific and cause immediate responses. They also use sensory receptors to monitor changes called stimuli. This is where gathered information creates sensory input. Integration is the processes and interprets sensory input which affects a response and creates motor output. Central Nervous System (CNS) consists of the brain and spinal cord. They occupy the dorsal body cavity and acts as integrating and commanding centers. They interpret incoming sensory information. In the sensory division nerve fibers convey impulses to the Central Nervous System while the motor division carries impulses from CNS to effector organs, muscles, and glands (Marieb 2003).
The neuron’s anatomy consists of the cell body (also known as the metabolic center of the cell) which contains the nucleus and abundant in nissl substance and neuro-fibrils. There are also the fiber
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Glioblastoma cells express Ca2+ -permeable AMPA-type glutamate receptors that are involved in the migration response. Their overexpression resulted in migration and proliferation, and their conversion to Ca2+ -impermeable receptors inhibited cell migration and induced apoptosis. So, inhibition of these receptors might prevent glioblastoma invasion (Miller, R., & Perry, A. 2007). Glioblastoma also may arise through 2 distinct pathways of neoplastic progression. Tumors that progress from lower-grade (II or III) astrocytic tumors typically display both well-differentiated and poorly differentiated foci. Secondary GBMs develop in younger patients, with time to progression from lower-grade lesions ranging from months to decades. Primary and secondary GBMs also harbor distinct molecular genetic

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