Name: Alexis Vick Drawer/Group #: 12
PS ID #: 1059363 Three digit mutant code: 458
BIOL 3311 Fall 2014 Lab Section: 20091/Tu4
Date: 09/29/14 TA Instructor Name: Laura Montier
Drosophila Melanogaster: Decapentaplegic gene
The fruit fly, Drosophila Melanogaster, has been used for years as a model for genetics. The flies are small and easy to maintain in a lab, cost-efficient, and have a quick life cycle, all qualities that make this a prime organism to utilize for genetic research. The data and conclusions derived from this research can have long term effects on not just the understanding of genetics but on the treatment of human diseases. A disease of great personal and recent national interest, amyotrophic lateral sclerosis …show more content…
As dpp diffuses through the neighboring cells, it activates either the type I receptor, Thickveins (TKV) or saxophone (sax), or both. TKV must be activated for any response to dpp and sax is only activated at high levels of dpp. TKV is responsible for the growth of the wings. If the signal is overly amplified it can result in the overgrowth of the longitudinal wing vein. If dpp is not signaling to grow more, then it is captured and destroyed by the cell which contributes to this gradient of …show more content…
These gene is a vital part of the integrated process of development. In drosophila, it determines the dorsal-ventral axis and also controls the development of the fly’s wings. Without this axis, the determination of where appendages develop can be incomplete or incorrect resulting in wings or feet in the wrong places. Major mutations during development are often lethal. In addition, wing development is extremely important for both survival and reproduction in drosophila. Without wings, the fly will have great difficulty escaping any dangerous situations such as predators or drowning and it will also struggle with courting (because they cannot make the sound with their wings) and mating. There is still a significant amount of research that can be done on this gene. The numerous interactions can be more closely studied in order to understand the true extent of dpp’s effect on development. In addition, because dpp plays such a vital role in development across taxa including in sea anemome, frogs, and humans, research could be completed to better understand development and possibly assist in the rapidly developing field of in vitro fertilization in humans. In addition, this gene may be studied to see if it has as significant effect, as it does in drosophila, on adult appendages. The studies of this gene and where it can be found across different taxa is not the only thing that can make a remarkable change in science. It
PS ID #: 1059363 Three digit mutant code: 458
BIOL 3311 Fall 2014 Lab Section: 20091/Tu4
Date: 09/29/14 TA Instructor Name: Laura Montier
Drosophila Melanogaster: Decapentaplegic gene
The fruit fly, Drosophila Melanogaster, has been used for years as a model for genetics. The flies are small and easy to maintain in a lab, cost-efficient, and have a quick life cycle, all qualities that make this a prime organism to utilize for genetic research. The data and conclusions derived from this research can have long term effects on not just the understanding of genetics but on the treatment of human diseases. A disease of great personal and recent national interest, amyotrophic lateral sclerosis …show more content…
As dpp diffuses through the neighboring cells, it activates either the type I receptor, Thickveins (TKV) or saxophone (sax), or both. TKV must be activated for any response to dpp and sax is only activated at high levels of dpp. TKV is responsible for the growth of the wings. If the signal is overly amplified it can result in the overgrowth of the longitudinal wing vein. If dpp is not signaling to grow more, then it is captured and destroyed by the cell which contributes to this gradient of …show more content…
These gene is a vital part of the integrated process of development. In drosophila, it determines the dorsal-ventral axis and also controls the development of the fly’s wings. Without this axis, the determination of where appendages develop can be incomplete or incorrect resulting in wings or feet in the wrong places. Major mutations during development are often lethal. In addition, wing development is extremely important for both survival and reproduction in drosophila. Without wings, the fly will have great difficulty escaping any dangerous situations such as predators or drowning and it will also struggle with courting (because they cannot make the sound with their wings) and mating. There is still a significant amount of research that can be done on this gene. The numerous interactions can be more closely studied in order to understand the true extent of dpp’s effect on development. In addition, because dpp plays such a vital role in development across taxa including in sea anemome, frogs, and humans, research could be completed to better understand development and possibly assist in the rapidly developing field of in vitro fertilization in humans. In addition, this gene may be studied to see if it has as significant effect, as it does in drosophila, on adult appendages. The studies of this gene and where it can be found across different taxa is not the only thing that can make a remarkable change in science. It