Flawed Models Of Dna Structure Essay

1615 Words Nov 10th, 2016 7 Pages
Several incorrect models of DNA structure were explored, by Watson and others, before Watson and Crick settled on the correct structure. Write an essay explaining three of these incorrect structures, how and why they were developed, and what evidence eventually led to each being discarded.
One of the fundamental aspects of life, that is heredity, the passing of genetic information from one generation to the next was little understood even by the late 1940s. One of the reasons for this was it was argued what this hereditary material, known as genes, exactly was. The more attractive looking proteins? For the complexity of proteins seemed to allow the for the variation of genes which allow for the observed complexity of life. Then there was deoxyribonucleic acid (DNA), which many argued was too simple, looked upon as “a boring binding agent for the protein” (Maddox, 2003). It was not until Avery, McCleod and McCarty, advancing on Griffith’s “transforming principle”, established in their 1944 paper that it was DNA that carried the genetic information and not the proteins. Despite this, the structure of DNA continued to elude the scientific community until 1953 when James Watson and Francis Crick of the Cavendish Laboratory, Cambridge, determined the double helical structure. Their scientific breakthrough was formally recognised in 1962 when, alongside Maurice Wilkins of King’s College London, they were awarded to Nobel prize in Physiology or Medicine. Though the double helical…

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