Depression : A Clinical Disorder Essay

1649 Words Nov 12th, 2016 7 Pages
According to Comer, depression is a clinical disorder that causes considerable distress and impairment and features a range of symptoms, including emotional, motivational, behavioral, cognitive, and physical symptoms. Nevertheless, the picture of depression may vary greatly from person to person. Depression differs from sadness, in that sadness is context-specific, is proportional to the triggering loss, and ends when the loss situation ends (Comer, 2015).
Due to the fact that the biological approach suggests that individuals with major depressive disorder often have low levels of the neurotransmitters serotonin and noradrenaline (norepinephrine), methods of combatting depression mainly include antidepressant drugs to rectify these low levels by increasing serotonin and norepinephrine levels in the brain. There are currently three groups of drugs that reduce the symptoms of depression: monoamine oxidase (MAO) inhibitors, tricyclics, and second-generation antidepressants (Comer, 2015). Monoamine oxidase inhibitors block monoamine oxidase from degrading the neurotransmitter norepinephrine, resulting in a rise of norepinephrine activity and, in turn, a reduction of depressive symptoms. Approximately half of depressed patients who take MAO inhibitors are helped by them (Bon, 2012). The MAO inhibitors are reasonably effective in reducing depression, but they do produce various side effects, such as blocking the production of monoamine oxidase in the liver, leading to the…

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