Alzheimer 's Disease Is The Most Common Form Of Dementia Essay

1077 Words Sep 28th, 2016 5 Pages
Alzheimer’s disease is the most common form of dementia. Dementia is a cognitive disorder with two forms: neurodegenerative and vascular disorders. Neurodegenerative is a deterioration of the mind and vascular disorders are caused by a decreased blood supply to the brain.(Lewis et al., 2014, p. 1444) With Alzheimer’s disease, the brain starts to change with age and brain transmitters start to get covered with plaque, get tangled, louse connections, and cause death in some transmitters. These brain transmitters are called neurons. (Lewis et al., 2014, p. 1446)
Genes may also play a role in how likely a person is to get this disease especially if it is a close family member. Part of the difference between Alzheimer’s being present or not is the way a person processes a protein called β-amyloid. This protein can cause an inflammatory response and eventually cause death to neurons. An onset of the disease before the age of 60 is called early onset Alzheimer 's and professions have identified three different genes that when mutated cause the overproduction of β-amyloid (Lewis et al., 2014, p. 1446). These three genes are presenilin-1, presenilin-2, and APP genes. (Lewis et al., 2014, p. 1447)
Another genetic factor that could contribute to Alzheimer’s is the presence of an allele called epsiolon (E) 4-allele. An allele is a gene that is recessive. This allele may help to clear amyloid plaques and if mutated would inhibit it from doing so, aiding in late-onset Alzheimer 's. (Lewis…

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