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49 Cards in this Set
- Front
- Back
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Fraction of TB cases in India as a function of the total no of cases in the world |
25% or 1/4 |
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Prevalence of TB in India |
211 cases per lac / 26 lac cases annually |
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Incidence of TB in India |
171 per lac |
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Success rate since 2005 among smear positive cases |
85% |
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Current success rate among smear positive cases |
86% |
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Annual risk of TB infection |
1.5% or 75 new cases per lac population |
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% of communicable disease deaths due to TB |
17.6 |
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% of all deaths due to TB |
3.5 |
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TB mortality in India per Park 23rd |
19 per lac |
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Best parameter for evaluating trend of TB |
Incidence |
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Best practical index for estimating number of infectious cases |
Prevalence |
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One case of PTB infects how many persons on average in 1 year? |
10-15 |
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% reduction in infectivity with effective antimicrobial treatment? |
90% in 48 hours |
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Definition of TB control |
Prevalence of natural infection in the age group of 0-14 is of the order of 1% - currently 40% in India |
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Advisable daily upper limit for smear examination by 1 microscopist |
20 |
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Number of organisms per ml for sputum smear positivity |
10k |
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Current gold standard for TB diagnosis |
2nd generation NAAT |
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One TU is equal to how many mg of PPD |
0.00002 |
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Strength of TU used for routine testing by vaccinating teams in India |
1 TU of PPD in 0.1ml on the flexor surface of forearm |
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Inference of tuberculin test positivity in child under 2 yrs |
Indirect evidence if active lesion |
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Incentive to DOTS agent on completion of a patients treatment |
150 |
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Site of diagnosis of MDR |
Intermediate reference laboratories accredited to perform culture and sensitivity testing |
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Main reason for childhood TB |
Failure of TB control in adults |
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Commonest age for childhood TB |
1-4 years |
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Drug doses of H R Z E S in mg/kg1 |
10-15, 10, 35, 15, 30 |
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Condition for chemo prophylaxis in infants |
Smear positive mother or any other household members |
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Duration of chemo prophylaxis in infants |
3m initially - then do a mantoux - if positive continue for 6m, if negative stop and give BCG |
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Usual dose of BCG |
0.1mg in 0.1ml |
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Prevalence of MDR in new cases in India |
2.2% |
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Prevalence of MDR in retreatment cases in India |
15% |
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Objectives of RNTCP / DOTS wrt case detection and cure rate |
70 and 85 % respectively |
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Objectives of TB free India programme wrt case detection and cure rate |
90% detection 90% cure rate in new cases 85% cure rate in re treatment cases |
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Lifetime probability of developing disease in TB infected individuals who are otherwise normal |
5-10% |
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% of TB load in children |
10% |
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% of new cases in India that are pediatric |
5 % |
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Medium used for micro colony detection on solid media |
Middle Brook 7H11 agar |
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Medium used in radiometric BACTEC 460 TB method |
7H12 |
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Basis of BACTEC method |
Detects TB based on metabolism, reported in terms of growth index |
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Basis of MGIT 960 mycobacteria detection system |
O2 utilisation and subsequent intensification of O2 quenched fluorescent dye |
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Basis of MB/BACT system |
Colorimetric detection of CO2. It is a non radiometric, continuous monitoring system |
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Number of organisms that can be identified with PCR, provided appropriate sequences for MTB are selected |
10-1000 |
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MC target gene for PCR |
IS6110 |
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Site of Ghon's focus |
Upper part of lower lobe |
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Best sample for PCR, positivity of which indicates a definite diagnosis of TB |
CSF |
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Line probe assay - prerequisite, time taken, genes detected |
Only for sputum smear positive pulmonary TB 2 days rpo B gene, kat G gene, inh A gene |
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Gene Xpert : prerequisite, time taken, genes detected |
Can be used in sputum smear positive pulmonary, smear negative, extrapulmonary 2 hrs rpo B gene only |
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Basis of quantiferon test |
PPD |
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Basis of quantiferon gold test |
ESAT 6 and CFP 10 |
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Basis of T spot TB |
RD 1 specific antigen |
