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6 Cards in this Set
- Front
- Back
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What are the determinants of O2 consumption that angina therapy seek to target?
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End diastolic volume (preload), blood pressure (afterload), heart rate, contractility, ejection time
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What drugs are used to treat angina?
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Beta-blockers, nitrates, and calcium channel blockers
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What do nitrates affect?
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Preload, by decreasing end diastolic volume. Venous relaxation shifts more blood volume into the veins.
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What do beta-blockers affect?
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Afterload, by relaxing the heart (decreases contractility)
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What do calcium channel blockers affect?
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Nifedipine is similar to nitrates in effect; verapamil is similar to beta-blockers in effect
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These beta-blockers are contraindicated in angina
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Pindolol, acebutolol. They are partial beta-agonists.
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