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52 Cards in this Set

  • Front
  • Back

Abnormal variation in size of erythrocyte.

Anisocytosis

Abnormal variation in shape of the erythrocyte?

Poikilocytosis

Erythrocyte with a diameter of 9-12 microns.

Macrocytes

RBC shows a peripheral time of hemoglobin with a dark staining central area.

Target cell

RBC with the bull’s eye appearance.

Thalassemia


Liver disease


Post splenectomy

⬆️ in iron in the mitochondria of normoblasts.

Sideroblastic anemia

Chronic blood loss?

Iron deficiency

Iron deficiency anemia

Low serum iron, high TIBC

Polycythemia vera

Pancytosis

Not typically seen in the peripheral smear in megaloblastic anemia.

Spherocytes

⬆️ in osmotic fragility in RBCs.

Hereditary spherocytosis

Contain iron stained granules.

Siderocytes

Remnant of nuclear DNA in RBC?

Howell - Jolly body

RNA remains in RBC when stained with?

New methylene blue

Cabot rings found in?

Erythrocytes

Excess membrane for cell volume (bull’s eye).

Target cell

Decreased cell membrane with same cell volume.

Spherocytes

Pitting” of red blood cell inclusion by spleen.

Bite cell

Crystallization of abnormal hemoglobin during oxygen deprivation.

Sickle cell

RNA inclusion.

Reticulocyte

DNA inclusion?

Howell - jolly body

Iron inclusion?

Pappenheimer body

Hemoglobin inclusion?

Heinz body

Decreased white cells, red cell and platelets.

Pancytopenia

Granulocytes released prematurely to myelocyte stage.

Left shift

⬆️ polychromasia?

Reticulocytosis

WBC count >50,000 /ul?

Leukomoid reaction

WBC inclusion?

Dohle bodies

G6PD deficiency.

Hexose monophosohate shunt (HMP)

Pelger huet anomaly.

2 lobes & hyperclumped chromatin

Lupus cells (LE), most probable source of confusion?

Tart cells

Maybe confused with a shift to the left?

Pelger-Huet

Stain that differentiates AML from ALL?

Peroxidase

Philadelphia chromosome.


A low neutrophil alkaline phosphatase NAP/LAP is seen in?

CGL (Chronic granulocytic leukemia)

Auer rods.

Acute granulocytic leukemia

Increased titer or antinuclear antibody (ANA) aids in the diagnosis of?

SLE

Reed steinberg cells

Hodgkin’s disease

Increased basophils and or eosinophils in the early stages.

Chronic myelocytic leukemia

Leucopenia in >50% of ptxs with >90% massive splenomegaly is most likely?

Hairy cell leukemia

Peroxidase is negative for?

Lymphocytes

Most chronic lymphocytic leukemias are neoplasm of?

B lymphocytes

Giant, bizarre platelets, nRBCs & teardrop red blood cells?

Myelofibrosis

Last red blood cell precursor to retain the nucleus before it becomes an erythrocyte?

Metarubricyte

Stain positive for hairy cell leukemia?

ACP

Hodgkin’s disease.

High WBC count with neutrophilia, high ESR, low serum iron

*Requires fresh samples?

Myeloperoxidase & LAP

*Present in neutrophils but NOT in monocytes?

NAP/LAP

*RBC histogram

MCV & RDW

*ALL is diff from AML

ALL is negative to both peroxidase & esterase

*Appropriate screening for HbS

Sodium dithionite test

*Maturation time: 3-5 days, including tissue phase: 121 days

Erythrocytes

*Maturation time: hours to few days, life span including tissue phase: 9-10 days

Granulocytes