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52 Cards in this Set
- Front
- Back
Abnormal variation in size of erythrocyte. |
Anisocytosis |
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Abnormal variation in shape of the erythrocyte? |
Poikilocytosis |
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Erythrocyte with a diameter of 9-12 microns. |
Macrocytes |
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RBC shows a peripheral time of hemoglobin with a dark staining central area. |
Target cell |
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RBC with the bull’s eye appearance. |
Thalassemia Liver disease Post splenectomy |
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⬆️ in iron in the mitochondria of normoblasts. |
Sideroblastic anemia |
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Chronic blood loss? |
Iron deficiency |
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Iron deficiency anemia |
Low serum iron, high TIBC |
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Polycythemia vera |
Pancytosis |
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Not typically seen in the peripheral smear in megaloblastic anemia. |
Spherocytes |
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⬆️ in osmotic fragility in RBCs. |
Hereditary spherocytosis |
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Contain iron stained granules. |
Siderocytes |
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Remnant of nuclear DNA in RBC? |
Howell - Jolly body |
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RNA remains in RBC when stained with? |
New methylene blue |
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Cabot rings found in? |
Erythrocytes |
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Excess membrane for cell volume (bull’s eye). |
Target cell |
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Decreased cell membrane with same cell volume. |
Spherocytes |
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“Pitting” of red blood cell inclusion by spleen. |
Bite cell |
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Crystallization of abnormal hemoglobin during oxygen deprivation. |
Sickle cell |
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RNA inclusion. |
Reticulocyte |
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DNA inclusion? |
Howell - jolly body |
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Iron inclusion? |
Pappenheimer body |
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Hemoglobin inclusion? |
Heinz body |
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Decreased white cells, red cell and platelets. |
Pancytopenia |
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Granulocytes released prematurely to myelocyte stage. |
Left shift |
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⬆️ polychromasia? |
Reticulocytosis |
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WBC count >50,000 /ul? |
Leukomoid reaction |
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WBC inclusion? |
Dohle bodies |
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G6PD deficiency. |
Hexose monophosohate shunt (HMP) |
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Pelger huet anomaly. |
2 lobes & hyperclumped chromatin |
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Lupus cells (LE), most probable source of confusion? |
Tart cells |
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Maybe confused with a shift to the left? |
Pelger-Huet |
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Stain that differentiates AML from ALL? |
Peroxidase |
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Philadelphia chromosome. A low neutrophil alkaline phosphatase NAP/LAP is seen in? |
CGL (Chronic granulocytic leukemia) |
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Auer rods. |
Acute granulocytic leukemia |
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Increased titer or antinuclear antibody (ANA) aids in the diagnosis of? |
SLE |
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Reed steinberg cells |
Hodgkin’s disease |
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Increased basophils and or eosinophils in the early stages. |
Chronic myelocytic leukemia |
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Leucopenia in >50% of ptxs with >90% massive splenomegaly is most likely? |
Hairy cell leukemia |
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Peroxidase is negative for? |
Lymphocytes |
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Most chronic lymphocytic leukemias are neoplasm of? |
B lymphocytes |
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Giant, bizarre platelets, nRBCs & teardrop red blood cells? |
Myelofibrosis |
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Last red blood cell precursor to retain the nucleus before it becomes an erythrocyte? |
Metarubricyte |
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Stain positive for hairy cell leukemia? |
ACP |
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Hodgkin’s disease. |
High WBC count with neutrophilia, high ESR, low serum iron |
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*Requires fresh samples? |
Myeloperoxidase & LAP |
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*Present in neutrophils but NOT in monocytes? |
NAP/LAP |
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*RBC histogram |
MCV & RDW |
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*ALL is diff from AML |
ALL is negative to both peroxidase & esterase |
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*Appropriate screening for HbS |
Sodium dithionite test |
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*Maturation time: 3-5 days, including tissue phase: 121 days |
Erythrocytes |
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*Maturation time: hours to few days, life span including tissue phase: 9-10 days |
Granulocytes |