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40 Cards in this Set
- Front
- Back
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Term for platelet production. |
Megakaryocytopoiesis |
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T or F: Platelets are nucleated. |
False, anucleated. |
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Normal Value of Platelets |
150-400*10^9/L or 150,000-400,000/mm^3 |
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Average platelet diameter |
2-5um |
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Platelet Mean Platelet Volume |
8-10 fL |
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Platelet lifespan |
8-11 days |
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Platelet maturation time A. 5 days B. 10 days C. 30 days D. 120 days |
A. 5 days |
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2/3 of platelets are seen in A. Blood B. Spleen C. Liver D. Kidney |
A. Blood |
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1/3 of platelets are seen inA. BloodB. SpleenC. LiverD. Kidney |
B. Spleen |
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Increase platelets A. Splenectomy B. Splenomegaly |
A. Splenectomy |
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Decrease platelets |
A. Splenectomy B. Splenomegaly |
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Platelet megakaryocyte diameter A. 30-50 dm B. 8-10 dm C. 10-20 dm |
A. 30-50 dm |
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T or F: Platelet megakaryocyte are multilobulated. |
True |
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Platelets are derived from the _____ of the megakaryocyte. A. Nucleus B. Mitochondria C. Rough ER D. Cytoplasm |
D. Cytoplasm |
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Last to undergo mitosis A. BFU-Meg B. CFU-Meg C. LD-CFU-Meg |
B. CFU-Meg |
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Last to have nucleus A. BFU-MegB. CFU-MegC. LD-CFU-Meg |
B. CFU-Meg |
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Can't undergo karyokinesis A. BFU-MegB. CFU-MegC. LD-CFU-Meg |
D. LD-CFU-Meg |
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Myelocytic & erythrocytic precursor cells crosses the megakaryocyte cytoplasm to reach thr sinusoidal lumen? A. EmperopoiesisB. Terminal Differentiation |
A. Emperopoiesis |
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Series of stages in which microscopist begin to recognize their unique wright-stained morphology in bone marrow aspirates film. A. Emperopoiesis B. Terminal Differentiation |
B. Terminal Differentiation |
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Earliest recognizable stage in platelet. A. Megakaryoblast B. Promegakaryocyte C. Megakaryocyte |
A. Megakaryoblast |
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Plasma membrane blebs A. MegakaryoblastB. PromegakaryocyteC. Megakaryocyte |
A. Megakaryoblast |
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Reaches its full ploidy level A. MegakaryoblastB. PromegakaryocyteC. Megakaryocyte |
B. Promegakaryocyte |
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Nucleus is intensely indented and multilobulated A. MegakaryoblastB. PromegakaryocyteC. Megakaryocyte |
C. Megakaryocyte |
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Platelet shedding A. MegakaryoblastB. PromegakaryocyteC. Megakaryocyte |
C. Megakaryocyte |
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Best site for bone marrow aspirate? |
Posterior superior illiac crest |
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Non-granular A. Hyalomere B. Chromomere |
A. Hyalomere |
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Granular A. HyalomereB. Chromomere |
B. Chromomere |
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TPO is released by? (2) |
Liver & Kidney |
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TPO receptor site A. MPL B. CD34 C. CD41 D. CD42 |
A. MPL |
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Stem cell marker and CMP Marker A. MPLB. CD34C. CD41D. CD42 |
B. CD34 |
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Marker for IIb portion of gp IIb/IIIa A. MPLB. CD34C. CD41D. CD42 |
C. CD41 |
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Marker for Ib portion of gp Ib/IX/V A. MPLB. CD34C. CD41D. CD42 |
D. CD42 |
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RNA for TPO A. rRNA B. tRNA C. mRNA |
C. mRNA |
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All release TPO except A. Kidney B. Thymus C. Liver D. Smooth Muscle Cell E. Stromal Cell |
B. Thymus |
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T or F: TPO concentration is directly proportional to platelet and megakaryocyte |
Flase |
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Decrease RBC, WBC, PLT : Increase EPO, TPO A. Aplastic anemia B. Polycythemia vera C. Fanconi's Anemia D. Both A and C |
B. Both A and C |
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Decrease RBC, WBC, PLT : Increase EPO, TPO A. Aplastic anemiaB. Polycythemia veraC. Fanconi's AnemiaD. Both A and C |
B. Polycythemia vera |
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Acts with TPO to induce early differentiation of stem cells A. IL-3 B. IL-6 C. IL-11 |
A. IL-3 |
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Acts in the presence of TPO to enhance endomitosis, megakaryocyte maturation and platelet release. A. IL-3B. IL-6C. IL-11 D. Both A and C E. Both B and C |
E. Both B and C |
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Derived megakaryocyte growth stimulating peptide |
Acetylcholinesterase |
