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69 Cards in this Set
- Front
- Back
Cilostazol
|
Inhibits phosphodiesterase type III
(contraindicated in HF) -first line drug treating claudication symptoms in PAD |
|
Pentoxifyllin
|
-increase erythrocyte flexibility
-decrease plasma fibrinogen (treating claudication symptoms in PAD) |
|
Nifedipine
|
CCB
-clinical use in PAD |
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Amlodipine
|
CCB
-clinical use in PAD |
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Diltazem
|
Non-DHP CCB
-clinical use in PAD |
|
Epoprostenol
|
prostacyclin analogue
-IV - central venous catheter, 6 min 1/2 life |
|
Treprostinil
|
prostacyclin analogue
-subcutaneous infusion, IV, inhalation |
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Iloprost
|
prostacyclin analogue
-inhalation - 20-30 min 1/2 life |
|
Bosentan
|
Endothelin Receptor Antagonists
-oral -blocks Endothelin A & B receptors -harmful to the liver -teratogen and decrease conc. of contraceptives |
|
Ambrisentan
|
Endothelin Receptor Antagonists
-oral -blocks Endothelin A receptors |
|
sildenafil
|
Phosphodiesterase type 5 inhibitor
-oral, IV |
|
Tadalafil
|
Phosphodiesterase type 5 inhibitor
-oral |
|
Captopril
|
ACE inhibitor
|
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Enalapril
|
ACE inhibitor
|
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Lisinopril
|
ACE inhibitor
|
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Ramipril
|
ACE inhibitor
|
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Quinapril
|
ACE inhibitor
|
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Fosinopril
|
ACE inhibitor
|
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Benazepril
|
ACE inhibitor
|
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Moexipril
|
ACE inhibitor
|
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Perindopril
|
ACE inhibitor
|
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Trandolapril
|
ACE inhibitor
|
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Losartan
|
Angiotensin II Receptor Antagonists
|
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Valsartan
|
Angiotensin II Receptor Antagonists
|
|
Candesartan
|
Angiotensin II Receptor Antagonists
|
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Irbesartan
|
Angiotensin II Receptor Antagonists
|
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Telmisartan
|
Angiotensin II Receptor Antagonists
|
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Eprosartan
|
Angiotensin II Receptor Antagonists
|
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Metoprolol
|
Beta Blocker
|
|
Bisoprolol
|
Beta Blocker
|
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Carvedilol
|
Beta Blocker
|
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Digoxin
|
Na-K ATPase blocker
-raises intracellular Na levels |
|
Isosorbide dinitrate
|
Vasodilator
-increase NO in veins -> decrease preload |
|
Hydralazine
|
Vasodilator
-dilate arteries -> decrease afterload |
|
Nitroglycerin
|
increase NO mainly in veins
|
|
Nitroprusside
|
increase NO in both arteries and veins
|
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Nesiritide
|
recombinant human B-type natriuretic peptide (BNP)
-dilate arteries and veins -increase natriuresis -IV drug |
|
Dobutamine
|
-positive inotropic drug
activates Beta 1&2 and alpha |
|
Inamrinone
|
Phosphodiesterase inhibitors
-positive inotropic drug -SE - thrombocytopenia -do not use chronically |
|
Milrinone
|
Phosphodiesterase inhibitor
-positive inotropic drug -SE - hypotension, arrhythmia -do not use chronically |
|
Dopamine
|
activate dopaminergic, beta, alpha receptors
-positive inotropic drug -increase renal blood flow |
|
Quinidine
|
Sodium Channel Blocker
(IA) |
|
Procainamide
|
Sodium Channel Blocker (IA)
-IV, IM, oral drug |
|
Disopyramide
|
Sodium Channel Blocker (IA)
-negative inotropic drug |
|
Moricizine
|
Sodium Channel Blocker (IA)
|
|
Lidocaine
|
Sodium Channel Blocker (IB)
-does not block K channels -works in ventricles -IV drug |
|
Mexiletine
|
Sodium Channel Blocker (IB)
-oral drug -does not block K channels -works in ventricles |
|
Flecainide
|
Sodium Channel Blockers (IC)
-do not use if pt has structural heart disease |
|
Propafenone
|
Sodium Channel Blockers (IC)
-also blocks beta receptors |
|
Propranolol
|
Beta Blocker
|
|
Nadolol
|
Beta Blocker
|
|
Timolol
|
Beta Blocker
|
|
Pindolol
|
Beta Blocker
|
|
Carteolol
|
Beta Blocker
|
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Levobunolol
|
Beta Blocker
|
|
Metoprolol
|
Beta Blocker
|
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Atenolol
|
Beta Blocker
|
|
Acebutolol
|
Beta Blocker
|
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Betaxolol
|
Beta Blocker
|
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Bisoprolol
|
Beta Blocker
|
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Esmolol
|
Beta Blocker
|
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Amiodarone
|
K channel blocker
|
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Dronedarone
|
K channel blocker
|
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Sotalol
|
K channel blocker
-non selective beta blocker |
|
Ibutilide
|
K channel blocker
-IV drug -conversion of atril fibrillation and flutter to NSR |
|
Dofetilide
|
K channel blocker
|
|
Dofetilide
|
K channel blocker
-oral drug -conversion of atrial fibrillation and flutter to NSR -chronically to maintain NSR |
|
Verapamil
|
CCB
-AV nodal reentrant tachycardia, slow vent. rate in pt with atrial fibrillation or flutter, narrow QRS atrioventricular reentrant tachycardia |
|
Adenosine
|
-activate adenosine receptors
--IV drug -decrease conduction velocity in AV node, increase refractoriness in AV node |