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48 Cards in this Set

  • Front
  • Back

Extra types of cell damage

-Nutritional deficits


-Imbalance of fluids and electrolytes

Abnormal metabolites and cell damage

-genetic disorders


-inborn errors of metabolism


-altered metabolism

Microorganisms

Bacteria and viruses

Chemical toxins of cells

-Exogenous: from environment


-Endogenous: from inside the body

Mechanical damage of cells

Pressure or tearing of tissue

Physical damage to cells

-excessive heat or cold


-radiation exposure

Hypoxia

Reduced oxygen in tissues

Ischemia

Deficit of oxygen in the cells

Apoptosis

Programmed cell death


•normal occurrence in the body

Neoplasia

"New growth"


Commonly called tumor

Anaplasia

Undifferentiated cells with variable nuclear and cell structures

Dysplasia

Cells vary in size and shape within a tissue

Metaplasia

Mature cell type is replaced by a different mature cell type

Hyperplasia

Increased number of cells


•results in enlarged tissue mass

Hypertrophy

Increase in cell size


•results in enlarged tissue mass

Atrophy

Decrease in the size of cells


•results in reduced tissue mass

Notifiable or reportable diseases

Diseases that must be reported by the physician to certain designated authorities

Communicable diseases

Infections that can spread from one person to another

Prevalence

Number of new and old or existing cases in a specific population within a specified time period

Incidence

Number of new cases in a given population within a specified time period

Occurrence of disease

Tracked by incidence and prevalence

Pandemics

A higher number of cases of an infectious disease in many regions of the globe

Epidemics

When a higher that expected number of cases of an infectious disease occur within a given area

Mortality

Number of deaths resulting from a particular disease within a group

Morbidity

Number of people with a disease within a group

Epidemiology

Science of identifying the causative factors and tracking the pattern or occurrence of disease within a group

Rehabilitation

Maximizing function of diseases tissues

Prognosis

Probability for recovery or for other outcome

Convalescence

Period of recovery

Sequelae

Unwanted outcomes of primary condition

Therapy

Treatment to promote or slow disease progression

Complications

New secondary or additional problems

Precipitating factor

Condition that triggers an acute episode

Syndrome

Collection of signs and symptoms



Often affects more than one organ

Manifestations

Signs and symptoms of disease

Prodromal period

Early development of a disease



Signs and symptoms nonspecific or absent

Incubation period

Time of exposure to a microorganism and onset of signs and symptoms

Latent state

No symptoms, or clinical signs evident

Subclinical state

Pathologic changes with no obvious manifestations

Chronic disease

•Often milder


•Develops gradually


•Persists for a long time

Acute disease

•develops quickly


•marked signs


•short term

Liquefaction necrosis

Dead cells liquefy because of release of cell enzymes

Coagulative necrosis

Cell proteins are altered or denatured (coagulated)

Coagulative necrosis

Cell proteins are altered or denatured (coagulated)

Fat necrosis

Fatty tissues broken down into fatty acids

Caseous necrosis

Form of coagulation necrosis in which a thick, yellow, cheesy substance forms

Infarction

Area of dead cells as a result of oxygen deprivation

Gangrene

Area of necrotic tissue that has been invaded by bacteria