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125 Cards in this Set
- Front
- Back
Neuron |
A single nerve cell |
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Name 6 parts of a neuron |
Cell body Axon Axon hillock Dendrites Myelin Sheath Synaptic ending/bulbs |
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What does the cell body contain? |
Nucleus, cytoplasm and other organelles. |
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Nissl Bodies |
Granular material conmposed of many ribosomes and rough E.R |
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What is the cytoplasm in axon called? |
Axoplasm |
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What do axons lack? |
Free ribosomes & nissl Bodies |
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Axon |
One thin tube like process arising from cell body that condicts electricity away from cell body |
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Which component of a neuron cobtains most of the cytoplasm? |
Axon |
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Axon Hillock |
End of soma, controls generation of action potential ie. Nerve signal |
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Dendrites |
Receive excitation from other neurons, spiny in appearance. Carries signals toward cell body |
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What is another name for dendrites and axons? |
Fibers or processes |
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Synaptic Ending/Bulbs |
Ends of axon that release transmitter substances to propagate signal to othr neuron |
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What are four shapes of neuron? |
Unipolar, bipolar, pseudopolar, multipolar |
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What are 3 type of neurons? |
Sensory neuron Motor neuron Interneuron |
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Sensory Neuron |
Brings nerve impulse from sensory organs to central nrrvous system |
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Motor Neuron |
Condicts nerve impulse from central nervous system to effector (muscle fibre or gland) |
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Interneuron |
Found only within central nervous system. Relays nerve impulse between neurons in CNS |
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Neuroglial/Glial Cells |
Provide nutrition, support, communication and protection between neurons. |
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What ate two types of neuroglial cells and wgere sre they found? |
Schwann Cell: in perepheral nervous system Oligodendrpcyte: central nervous system |
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What is another name for a Schwann cell? |
Neurolemmocyte |
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Myelin Sheath |
Rich in lipid |
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What property do Schwann cells and oligodendrocytes provide axons? |
They encircle axons insulating them electrically |
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Neurolemma |
outermost layer of Schwann cells surrounding neurons |
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What role do neurolemma play in the healing of nerves? |
Does not degenerate after nerve injury but forms template for nerves to heal in PNS |
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Nodes of Ranvier |
gaps between Schwann cells |
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The distance between the nodes of Ranvier are called _________ |
Internodes |
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How does the myelin sheath affect the electrical current across the axoplasm? |
It increases the speed of propagation of electrical signal |
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Saltatory Conduction |
propagation of electrical currents across the axoplasm from one node of Ranvier to the next |
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What is used to measure electrical potential difference (voltage) between outside and inside of a neuron? |
Oscilloscope |
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Describe the charge of a neuron |
The inside of an axon is more negative compared to the outside |
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Resting Potential |
refers to the neuron having a negative membrane at rest |
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Describe the concentration of Na ions and K ions inside and outside of an axon |
There is a higher concentration of K ions on the inside of the axon than outside and a lower concentration of Na ions on the inside than outside |
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Aside from the concentrations of Na ions and K ions, what else affects the charge within an axon? |
higher concentration of negative organic ions (proteins) inside the cell than outside |
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Is membrane more permeable to Na ion or K ion? |
K ion |
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What factor of the axomembrane contributes to its charge? |
It is more permeable to K ions than Na ions. Since there is a lower concentration of K ions on outside, more K ions will leave the cell, crossing the axomembrane. this makes it so there are less positive charges on the inside than outside which in turn makes the interior of the axon have a negative charge |
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What is the rate of ions being pumped in and out? |
3 Na ions out for every 2 K ions in, to maintain a potential difference of more + charge on the outside than in which contributes to resting membrane potential |
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What causes the axomembrane to go from a negative charge to a positive charge? |
Stimulation o neuron causes axomembrane to increase its permeability to Na ions by opening up gates of Na+ channels |
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Refractory Period |
Period where another action potential cannot occur due to membrane potential being positive, period follows immediately after stimulation where nerve is unresponsive to further stimulation |
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What causes the axomembrane to go from a positive charge to a negative charge? Also known as repolarization
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Na ion channels close and K ion gates open in mebrane |
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Hyperpolarization |
Resting membrane potential becomes more negative than normal due to K ion pump being open longer than it should be |
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Nerve Impulse |
Due to stimulation of neuron and changing of polarity across axomembrane |
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How do myelenated fibers affect nerve impulses? |
Due to distances between nodes of Ravier |
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At which parts of the neuron does synapsing occur? |
The axon and dendrite |
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Which part of the axon is involved in synapses? |
Synpatic bulb (axonal ending) |
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What do synaptic bulbs contain? |
Vesicles with neurotransmitters |
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Synaptic Cleft |
gap between pre-synaptic membrane and post synaptic membrane, gap junction can also exist |
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Describe the process of snyapses |
1. Nerve impulse reaches pre synaptic membrane, opens up calcium ion gates |
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How does a neurotransmitter cause a nerve to become excited? |
Makes post synaptic membrane potential less (Decrease its negativity), called EPSP. Allows more Na ions to come inside cell |
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How does a neurotransmitter cause a nerve to become inhibited?
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Makes post synaptic membrane potential increase (more negative) IPSP |
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What does an EPSP have to do to cause an action potential? |
1. Be great enough to reach threshold potential (-50mV) |
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Summation |
net effect of all excitatory and inhibitory neurotransmitters the cell receives |
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What is the all or none response? |
The strength of stimulus does not affect the strength of which a nerve or muscle fibre responds. It only matters if the voltage reaches the threshold or not |
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Name 5 nerotransmitters |
Acetylcholine, norepinephrine, serotonin, dopamine and GABA |
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What type of molecules are neurotransmitters? |
aminoacids, peptides or even gases |
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What happens to neurotransmitters once the receptors of the post synaptic nerve releases them? |
They are destroyed by enzymes in synapse or taken up by post or pre synaptic membrane to be repackaged or destroyed to prevent overstimulation or overinhibition |
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What is the function of acetylcholinesterase? |
break down actycholine |
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MAO |
monoamine oxidases break down serotonin, norepinephrine, and dopamine |
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Where are neurotransmitters created? |
in cell body, soma |
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Central Nervous System |
neurons only found in brain and spinal cord |
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Peripheral Nervous System |
Nerves connected to CNS but resides outside of CNS |
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Which group of nerves is the PNS made of? |
cranial, spinal and of the autonomic N.S |
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Nerves |
bundles of neurons with their cell bodies found in CNS or in ganglia |
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Ganglia |
collection of nerve cell bodies outside of CNS |
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What two groups is the PNS divided into? |
Somatic (voluntary control) |
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Cranial Nerves |
connect to brain |
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How many cranial nerves are there? |
12 pairs |
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What are 5 types of spinal nerves? |
Cervical |
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Where a spinal nerves found? |
come out between vertebrae of spine |
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Are spinal nerves somatic or autonomic? |
Both |
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Are spinal nerves motor or sensory? |
Both |
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Where do sensory fibres enter the spinal cord? |
Dorsal root |
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Where do motor fibres exit spinal cord? |
Ventral root |
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What is responsible for reflex responses? |
Spinal nerves, both sensory and motor |
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Which nerves are known as mixed nerves? |
Spinal nerves |
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Where do you find cerebrospinal fluid? |
central canal of spinal cord, ventricles of brain and separating meninges |
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What is cerebrospinal fluid for? |
nourishment to nerve cells |
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Meninges |
layers of connective tissues that protects spinal cord |
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Reflex Arc |
nerve pathway that carries out reflex |
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Describe the process of a reaction |
Receptor activated ---> sensory neuron ---> dorsal root----> dorsal cord ---> interneuron ----> ventral cord ----> motor neuron ---> effector (muscle or gland) |
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Autonomic Nervous System |
involuntary unconscious control |
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What does the autonomic nervous system control? |
smooth muscle, internal organs and glands of body |
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Does autonomic nervous system have motor or sensory neurons? |
motor |
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What is the autonomic nervous system divided into? |
Sympathetic and parasympatheticq |
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Which type of neurons send information about state of organs to CNS? and what responds to this? |
Sensory neurons in somatic nerves. |
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What type of neuron does the sympathetic nervous system have? |
short myelenated ---> ganglai ----> long unmyelenated |
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What type of neuron does the parasympathetic nervous system have?
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long myelenated ---> ganglai ----> short unmyelenated
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When does the sympathetic nervous system activate? |
During emergency situations, fight or fligth |
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Where do cell bodies of the pre-synaptic cell lie? |
thoracic and lumbar part of spinal cord |
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Describe the structure of the sympathetic nerves |
1. cell bodies in thoracic and lumbar parts of spinal cord |
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What is the neurotransmitter released by postganglionic neuron? |
norapinephinerine |
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What does the parasympathetic system cause? |
internal body responses associated with relaxtion |
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What is the neurotransmitter on postganglionic neuron? |
acetylcholine |
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Where are the cell bodies of pre-synaptic neurons in the parasympathetic nervous system found? |
Medulla and from sacral regions of spinal cord |
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Where does the synapse occur between the post synaptic neuron and pre synaptic neuron? |
Near or inside organs |
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Most but not all organs are innervated by both systems, true or false |
true |
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Which organs are only innervated by the sympathetic nervous system? |
adrenal medulla and sweat glands |
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What layer protects the brain? |
Meninges |
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Meningitis |
infection of meninges |
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What are the 4 parts of the brain stem |
midbrain, pons and medulla |
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What is the basic life support centre of the body? |
Brain stem |
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what is known as "primitive brain"? |
brain stem |
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Medulla |
1. Regulates heartbeat |
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Pons |
1. Reflex centre for head movement in response to visual and auditory stimuli |
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Midbrain |
Reflex centre for visual, auditory, and tactile responses |
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Diencephalon |
made of thalamus and hypothalamus |
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Hypothalamus |
1. Control centre for all autonomic regulatory activity in body |
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Thalamus |
1. Relay station, taking sensory information from all body processes and sends information to appropriate parts of brain |
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What is known as the master gland? |
Pituitary glands since it controls many functins of other glands |
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What type of hormones are secreted by the neurosecretory cells into the posterior pituitary gland? |
ADH (antidiuretic) aka vapopressin |
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What are the effects of ADH? |
promotes reabsorbtion of water by collecting ducts of kidneys and constriction of arterioles |
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What are the effects of oxytocin? |
contraction of uterus and release of milk from mammary glands |
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Cerebellum |
coordinates movement |
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Cerebrum |
largest part of brain |
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What is the outer layer of the cerebrum called? |
cerebral cortex |
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Cerebral Cortex |
gray matter, cell bodies and short unmyelinated fibres |
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White matter |
axons and myelinated fibres |
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What is the cerebrum joined together by? |
corpus callosum |
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What are the 3 areas that the cerebrum has? |
association |
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Association area |
Takes in info to make sense out of it |
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What controls voluntary activity in cerebrum? |
basal nucleii in cortex |
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What stimulates the adrenal glands? |
ANS and indirectly by hypothalamus |
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Which hormones are released by adrenal cortex at times of stress? and what do they do? |
mineralocorticoids and glucocorticoids |
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Which hormones are released by adrenal medulla and when? |
Epinephrine (adrenaline) and norepinephrine (noradrenaline), during emeregncy situations |
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What controls adrenal medulla? |
ANS |
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What are the effects of epinephrin and norepinephrine on body? |
1. metabollic rates goes up |