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125 Cards in this Set

  • Front
  • Back

Neuron

A single nerve cell

Name 6 parts of a neuron

Cell body


Axon


Axon hillock


Dendrites


Myelin Sheath


Synaptic ending/bulbs

What does the cell body contain?

Nucleus, cytoplasm and other organelles.

Nissl Bodies

Granular material conmposed of many ribosomes and rough E.R

What is the cytoplasm in axon called?

Axoplasm

What do axons lack?

Free ribosomes & nissl Bodies

Axon

One thin tube like process arising from cell body that condicts electricity away from cell body

Which component of a neuron cobtains most of the cytoplasm?

Axon

Axon Hillock

End of soma, controls generation of action potential ie. Nerve signal

Dendrites

Receive excitation from other neurons, spiny in appearance. Carries signals toward cell body

What is another name for dendrites and axons?

Fibers or processes

Synaptic Ending/Bulbs

Ends of axon that release transmitter substances to propagate signal to othr neuron

What are four shapes of neuron?

Unipolar, bipolar, pseudopolar, multipolar

What are 3 type of neurons?

Sensory neuron


Motor neuron


Interneuron

Sensory Neuron

Brings nerve impulse from sensory organs to central nrrvous system

Motor Neuron

Condicts nerve impulse from central nervous system to effector (muscle fibre or gland)

Interneuron

Found only within central nervous system. Relays nerve impulse between neurons in CNS

Neuroglial/Glial Cells

Provide nutrition, support, communication and protection between neurons.

What ate two types of neuroglial cells and wgere sre they found?

Schwann Cell: in perepheral nervous system


Oligodendrpcyte: central nervous system

What is another name for a Schwann cell?

Neurolemmocyte

Myelin Sheath

Rich in lipid
Schwann cells and oligodendrocytes circling the axons forming this sheath

What property do Schwann cells and oligodendrocytes provide axons?

They encircle axons insulating them electrically

Neurolemma

outermost layer of Schwann cells surrounding neurons

What role do neurolemma play in the healing of nerves?

Does not degenerate after nerve injury but forms template for nerves to heal in PNS

Nodes of Ranvier

gaps between Schwann cells

The distance between the nodes of Ranvier are called _________

Internodes

How does the myelin sheath affect the electrical current across the axoplasm?

It increases the speed of propagation of electrical signal

Saltatory Conduction

propagation of electrical currents across the axoplasm from one node of Ranvier to the next

What is used to measure electrical potential difference (voltage) between outside and inside of a neuron?

Oscilloscope

Describe the charge of a neuron

The inside of an axon is more negative compared to the outside

Resting Potential

refers to the neuron having a negative membrane at rest

Describe the concentration of Na ions and K ions inside and outside of an axon

There is a higher concentration of K ions on the inside of the axon than outside and a lower concentration of Na ions on the inside than outside

Aside from the concentrations of Na ions and K ions, what else affects the charge within an axon?

higher concentration of negative organic ions (proteins) inside the cell than outside

Is membrane more permeable to Na ion or K ion?

K ion

What factor of the axomembrane contributes to its charge?

It is more permeable to K ions than Na ions. Since there is a lower concentration of K ions on outside, more K ions will leave the cell, crossing the axomembrane. this makes it so there are less positive charges on the inside than outside which in turn makes the interior of the axon have a negative charge

What is the rate of ions being pumped in and out?

3 Na ions out for every 2 K ions in, to maintain a potential difference of more + charge on the outside than in which contributes to resting membrane potential

What causes the axomembrane to go from a negative charge to a positive charge?

Stimulation o neuron causes axomembrane to increase its permeability to Na ions by opening up gates of Na+ channels
Na ions move into cell because there is a higher concentration of Na ions on outside of cell than inside and because of negative ions on inside of axon
this causes the inside of membrane to turn + also known as depolarization

Refractory Period

Period where another action potential cannot occur due to membrane potential being positive, period follows immediately after stimulation where nerve is unresponsive to further stimulation

What causes the axomembrane to go from a positive charge to a negative charge? Also known as repolarization

Na ion channels close and K ion gates open in mebrane
K ions move outside of cell due to concentration gradient and repulsive forces due to excess of positive charge inside axon

Hyperpolarization

Resting membrane potential becomes more negative than normal due to K ion pump being open longer than it should be

Nerve Impulse

Due to stimulation of neuron and changing of polarity across axomembrane

How do myelenated fibers affect nerve impulses?



Due to distances between nodes of Ravier

At which parts of the neuron does synapsing occur?

The axon and dendrite

Which part of the axon is involved in synapses?

Synpatic bulb (axonal ending)

What do synaptic bulbs contain?

Vesicles with neurotransmitters

Synaptic Cleft

gap between pre-synaptic membrane and post synaptic membrane, gap junction can also exist

Describe the process of snyapses

1. Nerve impulse reaches pre synaptic membrane, opens up calcium ion gates
2. Calcium ion enters presynaptic bulb and reactions occur causing neurotransmitter to be released into synaptic cleft
3. Neurotransmitters diffuse across synaptic cleft and bind to receptors on post synaptic cleft
4. causes change in membrane potential of post synaptic cell which results in excitation or inhibition of post synaptic membrane

How does a neurotransmitter cause a nerve to become excited?

Makes post synaptic membrane potential less (Decrease its negativity), called EPSP. Allows more Na ions to come inside cell

How does a neurotransmitter cause a nerve to become inhibited?

Makes post synaptic membrane potential increase (more negative) IPSP

What does an EPSP have to do to cause an action potential?

1. Be great enough to reach threshold potential (-50mV)
2. Spread to axon hillock

Summation

net effect of all excitatory and inhibitory neurotransmitters the cell receives

What is the all or none response?

The strength of stimulus does not affect the strength of which a nerve or muscle fibre responds. It only matters if the voltage reaches the threshold or not

Name 5 nerotransmitters

Acetylcholine, norepinephrine, serotonin, dopamine and GABA

What type of molecules are neurotransmitters?

aminoacids, peptides or even gases

What happens to neurotransmitters once the receptors of the post synaptic nerve releases them?

They are destroyed by enzymes in synapse or taken up by post or pre synaptic membrane to be repackaged or destroyed to prevent overstimulation or overinhibition

What is the function of acetylcholinesterase?

break down actycholine

MAO

monoamine oxidases break down serotonin, norepinephrine, and dopamine

Where are neurotransmitters created?

in cell body, soma

Central Nervous System

neurons only found in brain and spinal cord

Peripheral Nervous System

Nerves connected to CNS but resides outside of CNS

Which group of nerves is the PNS made of?

cranial, spinal and of the autonomic N.S

Nerves

bundles of neurons with their cell bodies found in CNS or in ganglia

Ganglia

collection of nerve cell bodies outside of CNS

What two groups is the PNS divided into?

Somatic (voluntary control)
Autonomic (involuntary control)

Cranial Nerves

connect to brain

How many cranial nerves are there?

12 pairs

What are 5 types of spinal nerves?

Cervical
Thoracic
Lumbar
Saccral
Coccygeal

Where a spinal nerves found?

come out between vertebrae of spine

Are spinal nerves somatic or autonomic?

Both

Are spinal nerves motor or sensory?

Both

Where do sensory fibres enter the spinal cord?

Dorsal root

Where do motor fibres exit spinal cord?

Ventral root

What is responsible for reflex responses?

Spinal nerves, both sensory and motor

Which nerves are known as mixed nerves?

Spinal nerves

Where do you find cerebrospinal fluid?

central canal of spinal cord, ventricles of brain and separating meninges

What is cerebrospinal fluid for?

nourishment to nerve cells
shock absorber
cleansing CNS of metabollic waste

Meninges

layers of connective tissues that protects spinal cord

Reflex Arc

nerve pathway that carries out reflex

Describe the process of a reaction

Receptor activated ---> sensory neuron ---> dorsal root----> dorsal cord ---> interneuron ----> ventral cord ----> motor neuron ---> effector (muscle or gland)

Autonomic Nervous System

involuntary unconscious control

What does the autonomic nervous system control?

smooth muscle, internal organs and glands of body

Does autonomic nervous system have motor or sensory neurons?

motor

What is the autonomic nervous system divided into?

Sympathetic and parasympatheticq

Which type of neurons send information about state of organs to CNS? and what responds to this?

Sensory neurons in somatic nerves.
autonomic nerve system then causes changes in target organ they supply

What type of neuron does the sympathetic nervous system have?

short myelenated ---> ganglai ----> long unmyelenated

What type of neuron does the parasympathetic nervous system have?
long myelenated ---> ganglai ----> short unmyelenated

When does the sympathetic nervous system activate?

During emergency situations, fight or fligth

Where do cell bodies of the pre-synaptic cell lie?

thoracic and lumbar part of spinal cord

Describe the structure of the sympathetic nerves

1. cell bodies in thoracic and lumbar parts of spinal cord
2. axons exit cord and run to ganglia near cord where they synapse with post synaptic neurons whose cell bodies lies within sympathetic ganglion found within sympathetic trunk

What is the neurotransmitter released by postganglionic neuron?

norapinephinerine

What does the parasympathetic system cause?

internal body responses associated with relaxtion

What is the neurotransmitter on postganglionic neuron?

acetylcholine

Where are the cell bodies of pre-synaptic neurons in the parasympathetic nervous system found?

Medulla and from sacral regions of spinal cord

Where does the synapse occur between the post synaptic neuron and pre synaptic neuron?

Near or inside organs

Most but not all organs are innervated by both systems, true or false

true

Which organs are only innervated by the sympathetic nervous system?

adrenal medulla and sweat glands

What layer protects the brain?

Meninges

Meningitis

infection of meninges

What are the 4 parts of the brain stem

midbrain, pons and medulla

What is the basic life support centre of the body?

Brain stem

what is known as "primitive brain"?

brain stem

Medulla

1. Regulates heartbeat
2. breathing
3. vasoconstriction
3. reflex centre, vomiting, sneezing, coughing, hiccuping, swallowing

Pons

1. Reflex centre for head movement in response to visual and auditory stimuli
2. regulates breathing rate with medulla

Midbrain

Reflex centre for visual, auditory, and tactile responses

Diencephalon

made of thalamus and hypothalamus
regulates body functions and emotions

Hypothalamus

1. Control centre for all autonomic regulatory activity in body
2. maintains homeostasis
3. regulates hunger, sex drive, sleep, thirst, body temperature, water balance, blood pressure
4. controls pituitary gland, connection between nervous and endocrine system
5. makes ADH (vasopressin) and oxytocin by neurosecretory neurons which are stored in posterior pituitary gland

Thalamus

1. Relay station, taking sensory information from all body processes and sends information to appropriate parts of brain
2. regulates states of sleep, arousal or wakefulness (damage causes coma)

What is known as the master gland?

Pituitary glands since it controls many functins of other glands

What type of hormones are secreted by the neurosecretory cells into the posterior pituitary gland?

ADH (antidiuretic) aka vapopressin
Oxytocin

What are the effects of ADH?

promotes reabsorbtion of water by collecting ducts of kidneys and constriction of arterioles

What are the effects of oxytocin?

contraction of uterus and release of milk from mammary glands

Cerebellum

coordinates movement
processes info from inner ear to maintain balance
posture

Cerebrum

largest part of brain
consciousness
higher brain centre
memory
attention
perceptual awareness
thought
language

What is the outer layer of the cerebrum called?

cerebral cortex

Cerebral Cortex

gray matter, cell bodies and short unmyelinated fibres

White matter

axons and myelinated fibres

What is the cerebrum joined together by?

corpus callosum

What are the 3 areas that the cerebrum has?

association
motor
sensory

Association area

Takes in info to make sense out of it

What controls voluntary activity in cerebrum?

basal nucleii in cortex

What stimulates the adrenal glands?

ANS and indirectly by hypothalamus

Which hormones are released by adrenal cortex at times of stress? and what do they do?

mineralocorticoids and glucocorticoids
regulates amount of minerals and glucose in blood

Which hormones are released by adrenal medulla and when?

Epinephrine (adrenaline) and norepinephrine (noradrenaline), during emeregncy situations

What controls adrenal medulla?

ANS

What are the effects of epinephrin and norepinephrine on body?

1. metabollic rates goes up
2. blood glucose level goes up
3. bronchioles dilate to increases rate of breathing
4. blood vessels in skin and digestive tract constrict while those in skeletal muscles dilate
5. heart rate goes up and cardiac muscle contracts with more force