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31 Cards in this Set

  • Front
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Gas exchange

Uptake O2 and exhaling CO2

Partial pressure

Pressure exerted by a particular gas in a mix of gases (also applies to gas dissolved in liquid)


O2 is much less soluble in water than in air


Gases undergo net diffusion from region of higher pp t area of lower pp


ie: at sea level, the pressure of a column of atomosphere above us is 760 mm Hg. Atmosphere is 21% O2, 78% N2, and .04% CO2. O2 is 160 mmHg, N2 is 365 mmHg

Realities media

Breathing air is relatively easy and need not be very efficient


In a given volume, there is less O2 available in water than in air, concentration of O2 is lower in water than air (temp and salt impact this)


Obtaining O2 from water requires greater efficiency

Respiratory surfaces

Need large wet respiratory surfaces to exchange gases through diffusion( rate of diff. Is proportional to SA: the bigger, the faster)


Also need thin tissue


Respiratory surfaces vary by animal and can include skin gills trachea and lungs

Gills in aquatic animals

Gills are out folding of the body that create large SA for gas exchange


Ventilation moves respiratory medium over respiratory surfaces (swimming or brushing water over gills)

Countercurrent exchange

Used in fish gills


Blood flows in opposite direction of water passing over gills


Blood is always less saturated with O2 than the water it meets (this allows for higher pp to lower pp diffusion)


More than 80% of O2 dissolved in the water is removed as water passes over respiratory surface (allows super efficient)

Tracheal systems in insects

Have opening to outside and it branches inside that have cells attached to absorb (no blood absorbing)

Lungs

Unfolding of body surface


Circulatory system transports gases btw lungs and body


Size and complexity correlated with animals anabolic rate (horse lungs are huge)

Process of air travel

1. Filters through nose, warms it, humidified it, and samples odors


2. Pharynx directs air to the lungs and food to stomach (swallowing or breathing). Larynx moves upward and tips the epiglottis over the glottis to keep food from trachea

Air travels cont

3. Air passes


1. Pharynx


2. Larynx


4. Trachea


5. Bronchi


6. Bronchioles


7. Alveoli (where gas exchange occurs)


There is cartilage around trachea to hold windpipe open

Larynx

Just beyond the pharynx at top of trachea


Holds vocal cords (strips of elastic tissue that vibrate to create sound)


Cilia and mucus line epithelium of air ducts and move particles up to the pharynx


Mucus elevator: take particles that breathe in and move them up to dump into esophagus to be swallowed

Alveoli

Place of gas exchange


Air sacs at the tips of bronchioles (1,000 square feet)


Oxygen diffuses through the moist film of epithelium and into capillaries (inside alveoli)


Simple squamous epithelium. Thin due to only diffusion


Capillaries netting around alveoli


CO2 diffuses from the capillaries and into air space to exhale it

Surfactants

Secretions that coat surface of alveoli (disrupt surface tension)


Alveoli are so thin that they would collapse on themselves so they have surfactant


Alveoli are susceptible. They lack cilia and have whit blood cells, but too much is a problem (smoking, dust, and so on)

Babies and surfactants

Doesn’t develop until 33 weeks


Babes born premature do not have so at risk of realities distress syndrome


they will tx with artificial surfactant now

Positive pressure breathing

Amphibians


Forces air down trachea

Birds breathing

Have multiple sacs (8-9)


Breathe in twice to move air through so they don not mix spent air with fresh air


Highly efficient

Negative pressure breathing

Pulls air in


Long volume increases as rib and diaphragm muscles contract


Lungs are enclosed by plural sac sticking together lung and inside of thoracic cavity


When expanded this creates reduces pressure so from outside will come in to lower pressure


They relax on exhale creating pressure to move out CO2

Breathing

Tidal volume: volume inhaled with each breath (500mL)


Vital capacity: max tidal volume (w-3.4 L, m-a little more)


Residual volume: after exhalation, amount of air left in lungs

Control of breathing

Breathing is regulated involuntary breathing


Control centers found in the medulla oblongata


Medulla regulates the rate and depth of breathing in response to pH changes in cerebrospinal fluid


Also have stretch receptors that tell lungs you breathed enough

How the medulla oblongata regulates breath

Increase CO2 due to cellular respiration, you make a lot of acid


The more CO2 you have, the more carbonic acid you make which then makes your pH in your blood drop


This then drops in your cerebrospinal fluid also so MO increases rate and depth of breath to bring in more O2 as well as get rid of CO2 on more exhales


More O2 helps for more metabolism as well

Additional sensors

Sensors in aorta and carotid arteries monitor O2 and CO2 concentrations in blood


These signal breath controls


Additional moldulation of breathing in the pons, next to medulla and is involved with tempo

Circulation and gas exchange

1. Breathe in air, mix with air in lungs, has higher pO2. (160 to .2)


2. In alveoli, O2 moves to blood (in capillaries bc it has 40:45 ratio and higher to lower) and CO2 moves to air. It is now 104:40 ratio.


3. Blood goes from pulmonary vein to the heart and then to the body (systemic capillaries)


4. Exchange in capillaries of O2 and CO2 bc O2 diffuses to tissues and tissues give CO2 (think of cellular respiration and mitochondria). Ratio is now 40:45.


5. Travels the pulmonary arteries to the heart and then to the lungs where CO2 is exhaled again diffuses from higher to lower


Respiratory pigments

Proteins that help carry oxygen, increasing amount of oxygen that blood can carry


Exercising person would need to dissolve 2 L of blood per minute to get O2.=555 pumps per min). Due to these, needs to only pump 12.5

Hemocyanin

Respiratory pigment that uses copper as the oxygen-binding component


In anthropods and molluscsw

Hemoglobin

Respiratory pigment in vertebrate and some invertebrates


Contained within erythrocytes


Can carry 4 molecules of oxygen that bind to iron


Does this reversible: grabs on and let’s go of oxygen

Dissociation curve of hemoglobin

Small change in the partial pressure of oxygen can result in large change in delivery of O2

Cooperatively

Allosteric regulation


Binding of O2 on hemoglobin changes it’s shape which leads to greater affinity to oxygen molecules


The reverse is also true. When one releases oxygen, the others release

Bohr shift

Fold of protein changes due to pH (hemoglobin) when blood pH is more acidic


CO2 produced during cellular respiration lowers blood pH and decreases the affinity of hemoglobin for O2


Ventilation is controlled by pH of blood. pH is higher when more CO2 in blood (happens during high cell respiration). Tissues probably need more O2.


Hemoglobin and CO2 transfer

Hemoglobin assist in transferring CO2 to buffer blood


Carries about 7% of CO2.


70% of CO2 is transported in erythrocytes and reacts with water. Dissociates to hydrogen and bicarbonate ions (in buffer form)

Adaptations of diving mammals

Some seals and whales can dive deep and hold breath for about 2 hours


Some have a high blood to body volume ratio


Stockpile O2 and use it slowly


Have myoglobin proteins in muscles


Passive moving, keep blood from going to certain parts, and can use fermentation

Fetal hemoglobin

Fetal hemoglobin holds on to oxygen more than adult.


Allows fetus to extract oxygen from mother blood