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87 Cards in this Set

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Polymer

Nucleic Acids

What are the monomers of nucleic acids?

Nucleotides

Purines:

Adenine and Guanine

Pyrimidines:

Thymine, Cytosine, and Uracil

What does a nucleicacid consist of?

Pentose Sugar + Phosphate + Nitrogenous Base

What bonds hold nucleotides together?

phosphodiester bond

What are the 5 nitrogenous bases?

adenine, guanine, cytosine, uracil, thymine

What are the basepairing rules?

Adenine and Thymine (AT;forms 2 hydrogen bonds)


Cytosine and Guanine (CG;forms 3 hydrogen bonds)

What is the sugar in DNA?

Deoxyribose

What is the sugar in RNA?

Ribose

Explain Chargaffs Rules

Erwin Chargaff concluded that the amount of Adenine always equals the same amount of Thymine & the amount of Cytosine always equals the amount of Guanine

Who were the scientists that proposed the cell theory?

Mathias Schleiden and Theodor Schwam

What is the cell theory?

All living things are composed of cells


Cells are the smallest unit of life


Cells arise from preexisting cells

Explain why cells are relatively small

due to their reliance on diffusion of substances; large cells would increase diffusion time and be very inefficient

Give the features that are included in all cells

plasma membrane


cytosol


chromosomes


ribosomes

Explain differences between prokaryotes and eukaryotes:

Prokaryotes:


simplest organisms


DNA is present innucleoid


Cell wall outside of plasma membrane


Eukaryotes:


Possess membrane bound organelles


DNA enclosed in nucleus


Cytoskeleton for cellular structure

What is a ribosomes function?

Protein Synthesis

List all organelles in the endomembrane system:

Endoplasmic reticulum


Golgi apparatus


Lysosomes

Functions of Endoplasmic reticulum

Smooth ER: lipid synthesis, stores calcium ions, detoxifies


Rough ER: membrane factory of the cell; produces new membrane (some cells mayproduce proteins here due to the ribosomes embedded on ER

Function of Golgi Apparatus

modifies products of the ER;sorts and packages materials into vesicles (cis and trans faces)

Function of lysosomes(specialized vesicles)

arise from the Golgi; contains enzymes that break down macromolecules

What are vesicles?

Arise from the Golgi; serves as the transport medium in cell

What are mitochondria

Energy producing organelle(ATP)

How many membranes do mitochondria have?

2, double membrane (inner and outer)

What are the folds in the mitochondria called?

cristae

What are chloroplasts

specialized organelles inplants (and some eukaryotes) that are the sites of photosynthesis

what types of cells are chloroplasts found in?

plants and some eukaryotes

How many membranes do chloroplasts have?

2; double membraned

Explain the endosymbiotic theory:

Nonphotosynthetic eukaryote engulfed an oxygen using prokaryote that was capable of fixing oxygen, evolved to become mitochondria.


Nonphotosynthetic Eukaryote engulfed a photosynthetic prokaryote, evolved to become chloroplast. Now the initial eukaryote can fix oxygen and is photosynthetic

What two reasons are there to support the endosymbiotic theory

the mitochondria and chloroplast have their DNA molecules and have double membranes

What is the purpose of a cytoskeleton in acell?

to maintain cell structure

What are the 3 types of fibers that make up the cytoskeleton? give their functions

Microfilaments (actin) used in muscular contractions


Intermediate filaments (mainly keratin) anchors nucleus and other organelles, hold them in place


Microtubules (tubulin) cell mobility

What is the purpose of intercellular junctions?

way for adjacent to communicate and interact

Tight junctions, gap junctions, desmosomes

What is the current model that biologists use to refer to the plasma membrane?

Fluid mosaic model

In cells, what specific molecule is the bilayer composed of?

Phospholipids

What dophospholipids consist of?

Phosphate attached to a glycerol head and two fatty acid tails

what type of fatty acids the bilayer composed of?

unsaturated fatty acids

Give the function of cholesterol in the bilayer

Cholesterol acts like a buffer because it resists changes in membrane fluidity due to an increase/decrease in temperature

In integral proteins, is the region that is embedded in the bilayer nonpolar or polar?

nonpolar (hydrophobic)

Name the two types of membrane transport

Passive transport and active transport

What is passive transport?

Requires no input of energy; molecules diffuse across the membrane due to concentration gradients

what is diffusion?

movement of molecules from an area of high solute concentration to an area of low solute concentration

What is facilitated diffusion

movement of polar molecules across the membrane with the help of channel proteins or carrier proteins

What are the 3 conditions that determine movement direction in passive transport?

1. Difference in concentration gradient


2. voltage differences across membrane


3. Gated channels (need stimulus to open)

What is osmosis?

Net movement of water from an area of low solute concentration to an area of high solute concentration

Definition of hypertonic solution

solution that has a high solute concentration

Definition of Hypotonic solution

solution that has a low solute concentration

Definition of Isotonic solution

same osmotic concentration

What type of solution does an animal cell prefer to be in?

isotonic

What happens if an animal cell is placed in a hypertonic/hypotonic solution?

hypertonic: shrivels up


hypotonic: bursts (lyses)

What type of solution does a plant cell prefer to be in

hypotonic

what is active transport?

input of energy is required to move molecules up their concentration gradient (low to high concentration)

Give an example of active transport incells

Sodium Potassium pump

What is exocytosis?

when something exits the cell

What is endocytosis?

cell intakes something

3 types of endocytosis

Phagocytosis: cell takes up particulate matter


Pinocytosis: "celldrinking"


Receptor-mediated endocytosis: specific molecules are taken in after they bind to receptors on the membrane

What is energy?

Capacity to do work

What is potential energy?

Energy of position

What is kinetic Energy

energy of motion

What is thermodynamics

study of energy transformations

What are the 2 types of systems?

Isolated system: EX: liquid in thermos bottle (no transfer of energy)




Open system: energy that can be transferred between the system and the surroundings

Give the 2 laws of thermodynamics

1st: energy cannot be created or destroyed, only transferred/transformed




2nd: with every energy transformation, the entropy of the universe decreases

Explain why organisms don't violate the 2nd law of thermodynamics

although the entropy of the system itself is decreasing, the entropy of the system and its surroundings is always increasing

what is free energy?

the amount of available energy a system has to do work

Spontaneous reaction

some process or change that occurs without any outside help

nonspontaneous reaction

change that will happen only if energy is supplied

Does a spontaneous reaction require the input of energy?

no

what happens during a spontaneous change?

system becomes more stable; processes can be harnessed to do work

If my G (change in free energy) is positive,then my products have more free energy than my reactants

If my G (change in free energy) is negative,then my products have less energy than my reactants

What is an exergonic reaction?

proceeds with a net release of free energy. It is Catabolic

What is an endergonic reaction?

absorbs free energy from its surroundings(nonspontaneous). Anabolic

What is activation energy

the amount of energy required to initiate a chemical reaction

what are 2 ways in which the rate of a chemical reaction can be increased?

1. increasing temperature


2. lowering the activation energy (via enzymes)

what is a catalyst?

substance that influences chemical bonds in a way that lowers the activation energy

how do enzymes affect a chemical reaction?

lowers the activation energy of a reaction

what is an active site?

region on an enzyme where the substrate binds to

what factors can affect enzyme activity?

pH


Temperature

What is a competitive inhibitor?

inhibitor that competes with the substrate for the active site

What is a noncompetitive inhibitor?

inhibitor that does not compete with the substrate; binds the allosteric site and changes protein shape

What is feedback inhibition?

End product of pathway binds to an allosteric site on enzyme that catalyzes first reaction in pathway




Shuts down pathway so raw materials and energy are not wasted. Inition

What is a catabolic pathway?

pathway where there is a breakdown of complex molecules into simpler ones

what is an anabolic pathway?

process where complex molecules are made from simpler ones

ATP stands for


Adenosine Triphosphate

What is a Catalyst?

Substance that influences chemical bonds in a way that lowers activation energy










If the enzyme responsible for
converting A to C was mutated and nonfunctional, what would happen?





A:  A levels would increase; B, C, and D
levels would decrease. 
B:  A and B levels would increase; C
and D levels ...

If the enzyme responsible forconverting A to C was mutated and nonfunctional, what would happen?




A: A levels would increase; B, C, and Dlevels would decrease.


B: A and B levels would increase; Cand D levels would decrease.


C: A, B and C levels would increase; Dlevels would decrease.


D: A, B, C, and D levels would alldecrease.

B: A and B levels would increase; C and D levels would decrease.