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35 Cards in this Set

  • Front
  • Back

Direction of DNA Synthesis

DNA polymerase has 5′–3′ activity

What is meant by “antiparallel”

two molecules that are side by side but run in opposite directions.

Base pairing rules and how to use them to calculate DNA composition

A only bonds with T and C only bonds with G in a DNA strand.

Limitations of DNA polymerase

DNA polymerase is limited by the fact that it cannot add nucleotides in a 3' to 5' direction and that it cannot initiate synthesis on its own.

Leading strand


it is replicated continuously in the 3' to 5' direction.

Transcription

Transcription is the synthesis of RNA from a DNA template

DNA

DNA contains the instructions needed for an organism to develop, survive and reproduce.


Base pairing rules for DNA and RNA

adenine (A) pairs with uracil (U); guanine (G) pairs with cytosine (C).

Direction of RNA synthesis

RNA molecule with elongation occurring in the 5' to 3' direction.


Silent Mutation

a change in the sequence of nucleotide bases which constitutes DNA

Insertions/Deletions and Frame Shift Mutations

is a genetic mutation caused by indels (insertions or deletions) of a number of nucleotides in a DNA sequence that is not divisible by three.

The composition of DNA

Is made up of molecules called nucleotides

Structure of Chromosomes

is a DNA acid molecule with part or all of the genetic material of an organism

Interphase


G1


Cell grows


Mitosis (Karyokinesis)

is the division of nucleus.

Characteristics of Cancers

Cancerous cells divide excessively and can invade other tissues

Gametes

Cells with 1/2 of the genetic content of the parent cell (egg and sperm)

How organisms reduce Ploidy, and how The initial Ploidy is regained.

Meiosis I reduces the ploidy level from 2n to n

Homologous Chromosomes....what they are

Two or more chromosomes that contain the same genes in the same order

Prophase

chromosomes condense into compact,rodlike structures

Meiosis

produces 4 daughter cells, each of which are unidentical to the parent cell and to one another.


Lagging strand

one of two strands of DNA found at the replication fork, or junction, in the double helix

Translation

is the synthesis of a protein from an mRNA template

Anaphase

The spindle separates sister chromatids and pulls them toward opposite spindle poles

Telophase

2 daughter nuclei form and nuclear envelope reappears

Mitosis

produces 2 daughter cells which are genetically identical to the parent cell.

Translation

Translation is the synthesis of a protein from an mRNA template where the code in the mRNA is converted into an amino acid sequence in a protein

Pre-mRNA

The first (primary) transcript from a protein coding gene is often called a pre-mRNA and contains both introns and exons.

mRNA

Messenger RNA (mRNA) is a large family of RNA molecules that convey genetic information from DNA to the ribosome

tRNA

is a type of RNA molecule that helps decode a messenger RNA (mRNA) sequence into a protein

Missense Mutation

is a mistake in the DNA which results in the wrong amino acid being incorporated into a protein because of change

Nonsense Mutation

is a genetic mutation in a DNA sequence that results in a shorter, unfinished protein product

Interphase


S

DNA replicates

Interphase


G2

Cell grows and prepares for mitosis

Cytokinesis

is the division of the cytoplasm.