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35 Cards in this Set
- Front
- Back
Direction of DNA Synthesis |
DNA polymerase has 5′–3′ activity |
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What is meant by “antiparallel” |
two molecules that are side by side but run in opposite directions. |
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Base pairing rules and how to use them to calculate DNA composition |
A only bonds with T and C only bonds with G in a DNA strand. |
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Limitations of DNA polymerase |
DNA polymerase is limited by the fact that it cannot add nucleotides in a 3' to 5' direction and that it cannot initiate synthesis on its own. |
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Leading strand |
it is replicated continuously in the 3' to 5' direction. |
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Transcription |
Transcription is the synthesis of RNA from a DNA template |
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DNA |
DNA contains the instructions needed for an organism to develop, survive and reproduce.
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Base pairing rules for DNA and RNA |
adenine (A) pairs with uracil (U); guanine (G) pairs with cytosine (C). |
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Direction of RNA synthesis |
RNA molecule with elongation occurring in the 5' to 3' direction. |
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Silent Mutation |
a change in the sequence of nucleotide bases which constitutes DNA |
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Insertions/Deletions and Frame Shift Mutations |
is a genetic mutation caused by indels (insertions or deletions) of a number of nucleotides in a DNA sequence that is not divisible by three. |
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The composition of DNA |
Is made up of molecules called nucleotides |
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Structure of Chromosomes |
is a DNA acid molecule with part or all of the genetic material of an organism |
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Interphase G1
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Cell grows
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Mitosis (Karyokinesis) |
is the division of nucleus. |
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Characteristics of Cancers |
Cancerous cells divide excessively and can invade other tissues |
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Gametes |
Cells with 1/2 of the genetic content of the parent cell (egg and sperm) |
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How organisms reduce Ploidy, and how The initial Ploidy is regained. |
Meiosis I reduces the ploidy level from 2n to n |
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Homologous Chromosomes....what they are |
Two or more chromosomes that contain the same genes in the same order |
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Prophase |
chromosomes condense into compact,rodlike structures |
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Meiosis |
produces 4 daughter cells, each of which are unidentical to the parent cell and to one another.
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Lagging strand |
one of two strands of DNA found at the replication fork, or junction, in the double helix |
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Translation |
is the synthesis of a protein from an mRNA template |
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Anaphase |
The spindle separates sister chromatids and pulls them toward opposite spindle poles |
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Telophase |
2 daughter nuclei form and nuclear envelope reappears |
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Mitosis |
produces 2 daughter cells which are genetically identical to the parent cell. |
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Translation |
Translation is the synthesis of a protein from an mRNA template where the code in the mRNA is converted into an amino acid sequence in a protein |
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Pre-mRNA |
The first (primary) transcript from a protein coding gene is often called a pre-mRNA and contains both introns and exons. |
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mRNA |
Messenger RNA (mRNA) is a large family of RNA molecules that convey genetic information from DNA to the ribosome |
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tRNA |
is a type of RNA molecule that helps decode a messenger RNA (mRNA) sequence into a protein |
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Missense Mutation |
is a mistake in the DNA which results in the wrong amino acid being incorporated into a protein because of change |
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Nonsense Mutation |
is a genetic mutation in a DNA sequence that results in a shorter, unfinished protein product |
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Interphase S |
DNA replicates |
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Interphase G2 |
Cell grows and prepares for mitosis |
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Cytokinesis |
is the division of the cytoplasm. |