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78 Cards in this Set

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What are the primary structures of the digestive system? (7)

Mouth/oral cavity

Pharynx

Oesophagus

Stomach

Small Intestine

Large Intestine

Rectum and Anus

What are the accessory organs of the digestive system? (4)

Salivary glands

Liver

Pancreas

Gallbladder

What are the six processes of the digestive system?

1. Ingestion

2. Mechanical processing

3. Chemical digestion

4. Secretion

5. Absorption

6. Excretion

When does ingestion occur?




What muscles does it involve?




What process is this in digestion? (#)

Occurs when materials enter the digestive tract via the mouth.




Voluntary skeletal muscles.




#1







What does mechanical processing involve? (1)


What does it make? (1)


What process is this in digestion? (#)

- Crushing and shearing (in the mouth) for smaller particles


- Makes materials easier to propel along digestive tracts (moulding of food to fit in the tract)
- #2

1. What does chemical digestion involve?


2. What type of process is this?


3. What process is this in digestion? (#)

1. The chemical breakdown of food into small organic fragments for absorption by digestive epithelium


2. Molecular process


3. #3

1. What does the secretion process involve the release of?


2. Where is this released?


3. What # process is this in digestion?

1. The release of water, acids, enzymes, buffers and salts (bile)


2. By epithelium of digestive tract and glandular organs


3. #4

1. What does the absorption process move? What does this move across?


2. What # process is this in digestion?

1. Movement of organic substrates, electrolytes, vitamins and water. Across digestive epithelium into interstitial fluid of the digestive tract.


2. #5

What does the excretion process involve?




What # process is this in digestion?

Removal of waste products. Defecation.




#6

What are the key functions of the mouth/oral cavity? (5)

1. Ingestion


2. Sensory analysis (PTC in kale)


3. Lubrication


4. Mechanical processing.


5. Initiates chemical digestion.

1. What is the pharynx?


2. What type of processing is this?


3. Which three parts exists here? Top down.


4. What do the muscles do?

1. A common pathway for solid foods, liquids and air.


2. Mechanical processing (#2).


3. Oropharynx, laryngopharynx, oesophagus


4. Force the boulas down during swallowing.





What is the fancy word for swallowing?

Deglutition.

What is the oesophagus like in shape and size?




What is it lined with?

25-30cm long




Lined with stratified squamous epithelium

1. What is the oesophagus NOT involved with?


2. What processing is it involved in?


3. What moves from where to where, and via what mechanism?





1. No digestion/absorption.


2. Mechanical processing.


3. Boulas moves from pharynx to stomach via peristalsis.







What is peristalsis?

A series of wave-like muscle contractions that moves food to different processing stations in the digestive tract.

1. What is the stomach shaped like?


2. What is the size?

1. J-shaped.


2. 50mL to 1-1.5L depending on when you've eaten

What are the key functions of the stomach? (4)

1. Mechanical processing.


2. Chemical digestion.


3. Absorption.


4. Storage of food.

What does mechanical processing in the stomach involve?

Continued peristalsis mixes food boulas with chemicals (enzymes) to become chyme

Where does 95% of the absorption happen in the digestion system?

Small intestine.

What are the key functions of the small intestine? (3)

1. Mechanical digestion via peristalsis & segmentation


2. Chemical digestion (carbohydrate digestion, protein digestion, lipid digestion)


3. Absorption of nutrients.

What are the four parts of the large intestine? (4)

1. Large bowel


2. Cecum


3. Colon


4. Rectum

What are the key functions of the large intestine? (3)

1. Reabsorption


2. Absorption


3. Compaction and storage of fecal material prior to defecation

What does the large intestine to reabsorb? (2)

Water


Bile salts (transported in blood to liver)

What does the large intestine absorb? (4)

1. Nutrients (10%)


2. Minerals, short-chain fatty acids


3. Vitamins produced by bacteria e.g. vitamin K


4. Organic wastes

What are the eight essential nutrients?

Carbohydrates


Proteins


Lipids


Vitamins


Minerals


Electrolytes


Fibre


Water

Where does Vitamin K come from?

We have a symbiotic relationship with flora in out large intestine. Vitamin K is a cellular byproduct they produce when breaking down cellulose.

1) How does the digestion system handle each nutrient?


2) How must large organic molecules be broken down?


3) How must water, electrolytes & vitamins be processed?

1) Differently


2) Must be digested before absorption can occur.


3) Can be absorbed without processing, may require special transport.

1) What constitutes a large organic molecule?


2) How are these processed?

1) Carbohydrates, lipids, protein, nucleic acid


2) Must be digested before absorption can occur.

1) What are digestive enzymes?


2) What do they do?


3) Where do they act?


4) What do they act in (3)?

1) Proteins that help catalyse chemical reactions.


2) Break down molecular bonds in large organic molecules


3) Outside cells in the lumen


4) Mouth, stomach, S.I

What are digestive enzymes secreted by? (5)

1. Salivary glands


2. Tongue


3. Stomach


4. Pancreas


5. Intestinal microvilli (endothelial layer)

1. What does absorption remove?


2. What only is absorbed?


3. What does it go across?


4. & into what?

1. Organic substrates, electrolytes, vitamins and water


2. Simple molecules.


3. Digestive epithelium.


4. Into interstitial fluid of digestive tract

What breaks down starch?


Into what?


Which liquid?

Amylase into


Maltose


Saliva

What breaks down proteins? (2)


Into what?


from what juice??

Protease/Pepsin & Hydrochloric acid into


Partly digested proteins


in the gastric juice

What breaks down proteins, only via assistance of the pancreas?


Into what?

Proteases (trypsin) into peptides & amino acids

What breaks down peptides?


Into what? (4)


What type of enzyme?

Peptidases


Amino acids


Intestinal enzymes

What breaks down fats emulsified by bile?


Into what?


From which substance?

Lipases


Fatty acids and glycerol


Pancreatic juices

What breaks down starch, with assistance from pancreatic juices?

Amylase, into maltose.




This is also the same as the saliva.

What breaks down peptides, into what?




- Intestinal enzymes

Peptidases into amino acids

What breaks down sucrose? Into what?


What substances?

Sucrase into glucose and fructose


Intestinal enzymes

What breaks down lactose?


Into what? What substances?

Lactase


Into glucose and galactose


Intestinal enzymes

What breaks down Maltose? Into what?


What substance?

Maltase into glucose


Intestinal enzymes

- In absorption, where do substances move? (2)


- What moves into either category?

- Into the blood or lymphatic system


- Blood: Monosaccharides & amino acids via the hepatic portal system.


Lymphatics: fatty acids & monogylcerides

What are monosaccharides?

Carbohydrates.

Where does the hepatic portal system go to and from?

To liver from GI tract.

How are things transported across membranes in the digestive systems? (2)




Which is passive, which is active.

Diffusion. PASSIVE.




Carrier-mediated transport. ACTIVE.

What is carrier-mediated transport?

Compounds bind to integral protein for transport across membrane.

What are the (3) kinds of carrier-mediated transport?

1. Facilitated diffusion


2. Active transport


2. Cotransport

What is facilitated diffusion?


Is ATP required?

- Channels or carrier proteins passively transport one solute down a concentration gradient


- ATP not required

What is active transport?


What is up with concentration gradients?


Is ATP required?

Carrier proteins actively transport solutes.


Not dependent on concentration gradients.


Consumes ATP.

What is cotransport?


Is ATP required?

Carrier proteins move two solutes in the same direction


ATP might be required

What are the (3) ways water moves across the lining of the digestive tract?




AKA?

1. Passive water flow


2. Down osmotic gradient


3. To area of high solute concentration & low water concentration




AKA= water follows nutrients into cells/interstitial fluid

1. Where does most of the bodies water come from?


2. Where is most reabosorbed?


3. Where is the remainder absorbed?

1. Not from your diet. mostly from digestive secretion.


2. Small intestine


3. Large intestine, to compact feces

What ions must be regulated for homeostasis? (5)

Sodium, Potassium, Calcium, Iron, Magnesium

How is sodium transported in digestion?

Channel mediated diffusion, cotransport & active transport

How is potassium transported in digestion?

Channel mediated diffusion

How is calcium, iron and magnesium transported in digestion?

Active transport

What are vitamin compounds?

Organic compounds required in small quantities

What vitamins are fat soluble?


What is the transport mechanism?


What are the regulatory factors?

A, D, E, K


Diffusion


Absorbed along with fats, can be stored in liver

What vitamins are water soluble and transported by channel mediated diffusion?


What are the regulatory factors?

C, D




Follows concentration gradient


Not stored, excess excreted in urine



What vitamins are water soluble and transported by active transport?


What are the regulatory factors?

B12


Must be bound to intrinsic factor

What are the 4 layers of the digestive tract? Inner to outer.

Mucosa


Submucosa


Muscularis external (peristalsis)


Serosa (some, not all GI tract)

What is the inner layer of the GI tract called?


2) What is it made of?


3) What is an element/layer within that is special?

1) Mucosa


2) Mainly epithelial tissue


3) Muscularis mucosae (band of smooth muscles & elastic fibers)

What is the role of the mucosa? (3)

1. Absorption


2. Secretion of mucus, enzymes & hormones


3. Protection - lymphoid tissues

Where is there stratified squamous epithelium in the GI tract?




Why?

Oral cavity, pharynx, oesophagus




Mechanical stresses.

Where is there simple columnar epithelium in the GI tract?




Why?

Stomach, small intestine, large intestine

1) Where does the submucosa lie?


2) What is it?

1) Beneath the mucosa


2) Dense, irregular connective tissue

What lies in the submucosa? (5)

1. Blood & lymph vessels


2. Lymphatic nodules


3. Glands (buffers & enzymes)


4. Nerves, receptors


5. Sensory neurons

1) What is the main component of the muscularis externa?


2) What are the 2 layers?


3) What is the outer layer do? (2)


4) What does the inner layer do? (2)



1) Dominated by smooth muscle cells.


2) Outer longitudinal muscle layer, inner circular musc. layer


3) A) Mechanical processing B) Peristalsis.


4) Agitation. Form valves.



1. What is the serosa?


2. What is it made of?


3. Where is it absent in the GI tract?


4. What is its role?

1. Serous membrane covering muscularis externa.


2. Connective and epithelial tissue.


3. Not in oral cavity, pharynx, oesophagus & rectum


4. Protection

What 3 elements control digestion?

1. Enteric nervous system


2. Local and systemic control


3. Endocrine system

What is influenced by the ENS?

Motility, secretion and growth

1. What is the enteric nervous system?


2. What can it do, and what is this called?

1. 3rd division of the ANS, a network of neurons int he walls of the DT


2. Can carry out a response without input from the CNS. AKA short reflexes. (Reflexes integrated in CNS are long reflexes)

What are short reflexes?

Intrinsic neurons = completely within ENS i.e walls of gut

What are long reflexes?

Extrinsic neurons = bring signals from CNS to the digestive system.

1. When is the defecation reflex stimulated?


2. What process # is this?


3. What two reflexes does it involve?

1. When the rectum is stretched


2. #6


3. The intrinsic & parasympathetic defecation reflexes?

1. Where does the intrinsic defecation reflex operate?


2. When is it stimulated?


3. What does it innervate?

1. Entirely within the myenteric plexus - does not need the CNS!


2. Stimulated when the walls of the colon are stretched


3. Weak peristaltic movements, relaxation of the internal sphincter

This is an example of positive feedback.

1. When is the parasympathetic defecation reflex innervated?


2. What is its response?

1. Stretch in colon sends signals to spinal cords


2. Response: intensifies peristalsis & relax internal sphincter

This is an example of positive feedback.

What hormone is released in the small intestine first? What does it do?

GIP, which stimulates the release of insulin from the pancreas