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80 Cards in this Set
- Front
- Back
what are the four layers of the GI tract wall?
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(from esophagus-->anal canal)
1. mucosa 2. submucosa 3. muscularis externa 4. serosa |
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what type of epithelium surrounds the mouth, pharynx, esophagus, and anal canal?
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non-keratinized
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what three components make up the epithelial wall of the stomach?
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1. simple columnar
2. exocrine cells 3. enteroendocrine cells |
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what role does simple columnar play in the stomach?
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absorption with transport mechanism and secretory process
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what role does exocrine cells play in the stomach epithelium?
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mucous for protection and serous fluid for movement and action of enzymes (absorption)
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what role do enteroendocrine cells play in the stomach epithelium?
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secrete hormones into the blood
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what does the epithelium of the lamina propia (CT) consist of?
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1. blood and lymph vessels
2. MALT- mucosa associated lymphatic tissue |
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what organs are part of MALT?
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"pyers patches", tonsils, and appendix
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what is the muscularis mucosa?
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a thin layer of smooth muscle
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what are the 3 functions of the muscularis mucosa?
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1. increase surface area for secretion and absorption
2, folding in stomach 3. larger role: muscle tone of lumen itself |
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what 4 components make up the submucosa of the GI tract?
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1. areolar CT
2. blood and lymphatic vessels 3. submucosal plexus 4. glands and lymphatic tissue |
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what is the submucosal plexus?
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extensive network of neurons (plexus of meissner)
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what does the submucosa do?
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controls the secretion of the glans
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what is the muscularis externa dominated by?
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smooth muscle
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what 4 components make up the muscularis externa?
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1. innter circular sheet
2. myenteric plexus 3. outer longitudinal sheet 4. skii muscles mixed with smooth muscle in muscularis externa |
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what does the myenteric plexus do?
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controls contraction of muscularis externa
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where will you see serosa?
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in visceral abdominal cavity
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what does the serosa do?
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serous membrane that secretes serous fluid
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what is serosa also called?
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visceral peritoneum
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what is the serosa consist of?
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CT and simple squamos epithelium
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what three organs lack serosa?
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pharynx, esophagus, and rectum
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what is adventitia?
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outermost covering on digestive organs outside of the abdominal cavity; just CT
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what is the enteric nervous system?
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brain of our gut; esophagus-->anus
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what are the 2 plexuses of the enteric nervous system?
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1. submucosal
2. myenteric |
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what three type of neurons are within these plexuses?
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1. motor neurons
2. sensory neurons 3. interneurons |
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what do motor neurons do?
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-supply myenteric- controls motility
-supply submucosa- controls secretory cells (associated with glands) |
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what 2 types of sensory receptors are in the mucosal epithelium of the plexuses?
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chemoreceptors and stretch receptors
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what do interneurons do?
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-connect myenteric and submucosal plexus
-CNS and ANS ties/modifies (interneuron connections) |
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what are the two types of neural controls within the digestive system?
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1. extrinsic control
2. intrinsic ENS control |
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what 6 things that extrinsic control does?
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1. enteric system triggers small, sight, sound, and taste
2. direct motor control by CNS--> start things up to ENS 3. modification by ANS 4. affect of emotions 5. we get muscle contractions 6. salivary glands |
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what 5 types of neurons are involved in intrinsic ENS control?
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1. sensory neurons recieve signals from lumen going to ENS
2. motor neurons that drive smooth muscle 3. interneurons important for local reflexes 4. parasympathetic neurons 5. sympathetic neurons |
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what do motor neurons involve?
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-drive smooth muscle
-submucosal and myenteric plexus -secretions and contractions |
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what are interneurons important for?
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local reflexes; they ONLY connect submucosal plexus to myenteric plexus within GI tract (staying local)
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what do sympathetic neurons do?
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shuts enteric down
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what two type of hormones are involved in hormonal control of the digestive system?
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1. peptide hormones
2. endocrine hormones |
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what type of cells are involved with peptide hormones?
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enteroendocrine cells
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what are 3 functions of peptide hormones?
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1. released into CT and then blood vessels
2. enhance of inhibit muscle contraction 3. control secretion of gland cells release due to binding |
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what five components are part of the endocrine hormones?
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peptide hormones, insulin, glucagon, PTH, and calcitonin
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what are local mechanisms?
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chemicals in interstitial fluid that effect small areas
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how do the chemicals coordinate and 2 examples?
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in response to changing conditions
1. prostaglandins- fatty acids secreted that affect metabolic activities 2. histamine- initiates/enhances inflammatory response; initiate secretion of acids |
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what are the oral or buccal cavity accessory digestive organs?
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teeth and tongue
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what 3 components are involves in the tongue?
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1. extrinsic muscles
2. intrinsic muscles 3. lamina propria |
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what do the extrinsic muscles do?
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move food from side to side, in and out, back to front
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what do the intrinsic muscles do?
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reshape tongue to form words and swallowing
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what 2 things does the lamina propria contain?
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1. papillae-tastebuds
2. lingual glands |
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what do lingual glands do?
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secrete mucousy, serous fluid containing lingual lipase (begins digestion of triglycerides)
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what is enamel?
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-hardest substance in the body
-protection again bacteria acids |
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what are 2 functions of enamel?
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1. protects the tooth from wear and tear of chewing
2. protects against acids that easily dissolve dentin which forms majority of tooth |
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what is mastication?
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chewing, mov food around, saliva, and teeth
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what is the result of mastication?
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bolus (lump)
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what runs how much saliva we need?
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the CNS and cerebral cortex
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why is mouth moist?
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to decrease bacteria
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what are 2 functions of the salivary glands?
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1. saliva keeps mouth and pharynx moist
2. secretions increase when food arrives |
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how do the small salivary glands of mouth and toungue mucous membrane open?
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directly or through ducts to oral cavity
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what are the four ducts to oral cavity?
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labial, buccal, palatal, and lingual glands
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what are the 3 major salivary glands and where are they located?
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1. parotid glands-serous
2. submandibular glands- mixed 3. sublingual glands- mucous |
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why is majority of saliva water?
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because its a medium for dissolving food
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what are the 7 types of solutes in saliva?
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1. ions- chloride, phosphate, bicarbonate
2. glycoproteins 3. Antibodies 4. enzymes 6. wastes |
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what do bicarbonate and phosphate ions do?
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buffer acidic foods
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what do glycoproteins do?
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mucous, aids in formation of bolus
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what do Antibodies- IgA do?
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prevents invasion
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what do enzymes do?
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lysozyme; salivary amylase; kills bacteria
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what are wastes and what do they do?
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urea and uric acid; they rid of blood from digestive system
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what are the 3 phases of deglutition?
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1. buccal phase
2. pharyngeal phase 3. esophageal phase |
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what happens during the buccal phase of deglutition?
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-bolus is forced into oropharynx (back of throat with tongue)
-voluntary stage |
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what happens during the pharyngeal phase?
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bolus stimulates receptors in oropharynx, swallowing reflex begins
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what are the 4 steps of the pharyngeal phase?
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1. impulses sent to deglutition center in medulla oblagata
2. bolus moves through oropharynx and laryngopharynx 3. respiratory centers inhibited 4. esophageal sphincter reflexes to push bolus through |
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what does the uvula and soft palate do?
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lift up to block off nasopharynx
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what does the epiglottis do?
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closes the larynx
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what happens during the esophageal phase?
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bolus enter esophagus and is pushed toward the stomache
-long fibers-shorten, diameter widens |
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what are the three components of the esophagus's histology?
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1. smooth muscle in the muscularis mucosae
2. mucous glands in submucosa moisten food 3. muscularis externa- circular and longitudinal |
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what are the three divisions of the muscularis externa of the esophagus?
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1. Superior 1/3: skeletal muscle, voluntary
2. Middle 1/3: mixed smooth and skeletal, voluntary and involuntary 3. Inferior 1/3: smooth muscle only, involuntary |
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during esophageal phase of deglutition, what is the bolus being pushed by?
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peristalsis which is a progression of coordinated contractions and relacations of circular and longitudinal muscle layers pushing food down (shorten and lengthen; wave-like)
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what happens during peristalsis?
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-circular muscles superior to bolus contract
-longitudinal fibers inferior to bolus contract -controlled by neurons in myenteric plexus -contractions repeated in waves |
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when does the esophageal sphincter relax?
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-as bolus reaches end of esophagus
-bolus moves into stomach |
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what are the three steps of the esophangeal phase?
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1. bolus pushed by peristalsis
2. lower esophageal sphincter relaxes as bolus reaches end of esophagus 3. bolus moves into stomach |
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what are the four main regions of the stomach?
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1. cardia
2. fundus 3. body 4 pyloris |
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what is rugae?
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mucosal folds for expansion
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what is the pyloric sphincter??
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-connection to duodenum
-control release of chyme -regulated depending on chemical in area |
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what is the main/majority region of the stomach
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body
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