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178 Cards in this Set

  • Front
  • Back

The organ in an animals body that is the primary site of extravascular hemolysis is the

Spleen

Which of the following is a reasonable number for RBC count in a horse?

8,400,000 per microliter (cu mm)

Maternal Ab obtained by foal from colostrum provide

Passive immunity

Which of these is produced through the breakdown of heme from old RBC's?

Bilirubin

Yellow bone marrow is composed primarily of

Fat cells

Where would you look for the thymus in a young animal?

Cranial thorax

One hemoglobin molecule can carry how many molecules of oxygen?

4

An NRBC (nucleated RBC) is ______ a mature erythrocyte

Less mature than

A senescent erythrocyte is a/an _______ erythrocyte

Aged

When monocytes enter tissue they become

Macrophages

Polychromasia seen erythrocytes is a sign of


-dehydration


-immaturity


-acid/base imbalance


-cell death

Immaturity

If immature neutrophils are observed in peripheral blood, the condition is called a


-leukopenia


-left shift


-right shift


-leukemia

Left shift

The normal reference range for the hematocrit in an adult dog is 37%-55%. Allover, an adult Golden Retriever, has a hematocrit of 15%. This is an indication that Allover might

Be anemic

Cell mediated immunity is a function of


-T lymphocytes


-B lymphocytes


-cytokines


-neutrophils

T lymphocytes

The rate of erythropoietin is controlled by erythropoietin, which is a/an


-hormone produced by the kidney


-enzyme produced by the spleen


-hormone produced by the spleen


-enzyme produced by the kidney

Hormone produced by the kidney

What is true of vaccinations?


-the provide passive immunity


-the expose animal too antibody produced by the pathogen


-the expose animal to antigen produced by the pathogen


-the elicit only a non-specific immune response

They expose animal to antigen produced by the pathogen

Which organ is capable of storing blood that can be released into circulation when the animal needs it?

Spleen

Which mature blood cell is described as a non-nucleated biconcave disc?


-monocyte


-lymphocyte


-thrombocyte


-erythrocyte

Erythrocyte

Which set of vessels may contain one-way valves to prevent backflow?

Veins and lymph vessels

You would most likely see postprandial lipemia

Shortly after an animal has eaten

In a 3-year-old sheep most leukocyte production takes place in the

red bone marrow

Hematopoiesis is the formation of

RBC's, WBC's and platelets

Which of these is considered a PMN?


-lymphocyte


-monocyte


-neutrophil


-eosinophil

Neutrophil

Which of the following cells is most primitive?


-megakaryoblast


-pluripotential stem cell


-megakaryocyte


-unipotential stem cell

Pluripotential stem cell

Red blood cells normally mature in

The bone marrow

EDTA is a/an

Anticoagulant

Lymph from the digestive tract is called

Chyle

An irregular dark patch in skin or mucous membranes caused by hemorrhage


-epistaxis


-ecchymosis


-thrombocytopenia


-petechia


-thrombopathia

Ecchymosis

Coagulation disorder due to abnormal platelet function


-epistaxis-ecchymosis-thrombocytopenia-petechia-thrombopathia

Thrombopathia

Bleeding from the nose


-epistaxis-ecchymosis-thrombocytopenia-petechia-thrombopathia

Epistaxis

Pinpoint red spots on mucous membranes or skin caused by submucosal or intradermal hemorrhage


-epistaxis-ecchymosis-thrombocytopenia-petechia-thrombopathia

Petechia

Abnormally low number of platelets


-epistaxis-ecchymosis-thrombocytopenia-petechia-thrombopathia

Thrombocytopenia

You are looking at a stained smear of horse blood and you see a leukocyte with large red granules in its cytoplasm. What cell are you most likely seeing?

Eosinophil

Stercobilinogen is a breakdown product of


-globin


-heme


-amino acids


-liver cells

Heme

Which of the leukocytes is most prevalent in sheep?


-neutrophils


-monocytes


-lymphocytes


-basophils

Lymphocytes

Which of these cells can become an Antigen Presenter Cell?


-neutrophil


-T lymphocyte


-B lymphocyte


-maceophage

Macrophage

There are 13 clotting factors. What is the minimum number of factors that can be deficient or absent and blood will still clot?

0

Which of the following leukocytes will be found in large numbers at the site of a bite wound with bacterial contamination?


-erythrocytes


-B lymphocytes


-basophils


-neutrophils

Neutrophils

A megakaryocyte will eventually produce


-erythrocytes


-neutrophils


-thrombocytes


-monocytes

Thrombocytes

If an anticoagulant is used when collecting a blood sample, the fluid obtained from the sample after it has been centrifuged is

Plasma

Which vessel carries lymph into a lymph node?


-afferent lymph vessel


-thoracic duct


-lymph artery


-efferent lymph vessel

Afferent lymph vessel

The process by which neutrophils engulf invading foreign microorganisms is called

Phagocytosis

White blood cells use peripheral blood for

Transportation

Jaundice (icterus) could be a result of


-decreased intravascular hemolysis


-decreased amounts of conjugated bilirubin


-excessive amounts of unconjugated bilirubin


-excessive amounts of glucuronic acid

Excessive amounts of unconjugated bilirubin

This granulocyte's granules contain heparin


-basophils


-eosinophil


-lymphocyte


-neutrophil

Basophil

Along with tissue macrophages, which leukocytes make up the mononuclear phagocyte system?


-eosinophils


-monocytes


-lymphocytes


-neutrophils

Monocytes

During hemostasis which process occurs first?

Platelet adhesion

If you counted 95% neutrophils on a cow's differential white blood cells count and the normal range is 15% to 33%, this would be classified as a

Neutrophilia

Tonsils differ from lymph nodes in that they

Are not encapsulated

How many heme molecules are contained in one hemoglobin molecule?

4

One antibody type has thousands of antigen receptors on its cell surface. How many types of antigens will typically fit these receptors?

1

Which one of the following blood tests would measure the average size of an erythrocyte in a blood sample?


-mean corpuscular hemoglobin conc


-red cell distribution width


-reticulocyte count


-mean corpuscular volume

Mean corpuscular volume

The process by which blood is prevented from leaking out of damaged blood vessels is


-hematocytosis


-hemolysis


-hematopoiesis


-hemostasis

Hemostasis

The organ that is made up of white pulp and red pulp is the

Spleen

Mature platelets contain mitochondria but mature erythrocytes do not. Based on this information, which cell activities would you expect to occur in platelets but not erythrocytes?

Aerobic respiration

The lymph nodes caudal to the stifle are normally palpable in dogs.. these are the

Popliteal l.n.

An immature neutrophils with a horseshoe-shaped nucleus is called a

Band cell

Oxygen carried in a hemoglobin molecule is bound to a/an

Iron atom

Lymph passes through the ______ just before returning to blood circulation


-pulmonary vein


-portal vein


-mesenteric artery


-thoracic duct

Thoracic duct

What is the minimum number of nuclear lobes seen in a hypersegmented neutrophil?

6

An example of an agranulocytic leukocyte is a/an


-neutrophils


-erythrocyte


-lymphocyte


-basophil

Lymphocyte

The PCV is determined using


-whole blood with an anticoagulant added


-whole blood with no anticoagulant


-serum only


-plasma only

Whole blood with an anticoagulant added

You have just identified large numbers of Ancylostoma caninum on a fecal exam on a sick puppy, so you are not surprised by this finding on the CBC


-anemia


-polycythemia


-increased number of eosinophils


-A & C

A & C

The process by which a neutrophil squeezes between the cells of the endothelium to leave a blood vessel and enter tissue is called

Diapedesis

The most common immunoglobulin produced after an animal has been exposed to a pathogen for a long time is


-IgM


-IgG


-IgE


-IgA

IgG

Any organism that is capable of causing disease is considered a/an

Pathogen

What type of immunologic cell can protect an animal from a pathogen after the animal's initial exposure and during a subsequent exposure?

Memory B cell

Natural killer cells are part of


-the adaptive immune system only


-the innate immune system only


-both the innate and adaptive immune systems


-not part of the immune system

Both the innate and adaptive immune systems

Helper T cells help the immune response by secreting ____ into the surrounding tissue


-toxins


-hydrogen peroxide


-antibodies


-cytokines

Cytokines

Adaptive immunity


-is associated with erythrocytes


-is nonspecific


-is associated with memory cells


-is quick to respond to an invading organism

Is associated with memory cells

An immunoglobin is also known as a/an

Antibody

External innate immunity depends on

Intact skin

An attenuated vaccine contains

Modified live virus

The innate immune system


-is fast to respond to foreign invaders


-develops as the animal matures


-is dependent on the production of antibodies


-discriminates against certain types of foreign invaders

Is fast to respond to foreign invaders

Transplacental antibody transfer from mother to fetus is an example of

Passive immunity

What cell is responsible for immunity against intracellular pathogens?


-T lymphocytes


-B lymphocytes


-monocytes


-plasma cells

T lymphocytes

Chemotaxis is the process of

Attracting phagocytes to a site of injury

When an animal receives a vaccine, about how long will it take before the animal's immune system will protect the animal from disease?

2 weeks

Autoimmune hemolytic anemia results from a Type ____ reaction

Type II reaction

An animal's first line of defense against potential disease-causing organisms is the

Skin

Another name for programmed cell death is caused by NK cells is

Apoptosis

Where on the animal would you look for the popliteal lymph node?

Caudal aspect of the hamstring muscles

The first immunoglobulin produced by newborn animals is

IgM

The complement system can alter a microbial cell membrane through a process of ______ that makes the microbe more 'visible' to a phagocyte


-opsonization


-exocytosis


-chemotaxis


-leukopoiesis

Opsonization

Which blood cells becomes a macrophage when it enters tissue?

Monocyte

If you see a lymphocyte on a stained blood smear, it is most likely what type of lymphocyte?


-Kupffer cell


-T cell


-dendritic cell


-B cell

T cell

Lysosomes in the cytoplasm of a phagocyte contain

Digestive enzymes

The type of hypersensitivity reaction that can be associated with a severe allergic reaction from a second exposure to an Antigen is

Type I reaction

The immunoglobulin that protects body surfaces such as mucosal surfaces from foreign microorganisms us


-IgA


-IgM


-IgG


-IgE

IgA

The type of cytokine that is produced by virus-infected cells and attaches to the cell membranes of nearby cells is a/an


-interferon


-chemokine


-opsonin


-interleukin

Interferon

The two most important functions of the complement system are to alter microbial cell membranes and

Initiate an inflammatory response

Where do T lymphocytes mature?


-thymus


-spleen


-lymph nodes


-thyroid

Thymus

A dendritic cell is a macrophage found in


-liver


-bone


-lymph nodes


-nerve tissue

Lymph nodes

What type of cell will inhibit helper T cells and cytotoxic T cells?

Regulatory T cells

The virulence of a pathogen refers to

The relative strength of the pathogen

What cell is responsible for production, storage, and release of antibodies?


-T lymphocyte


-B lymphocyte


-parietal cell


-plasma cell

Plasma cell

Which specific type of immunity is involved in antibody production?


-cell-mediated


-adaptive


-humoral


-innate

Humoral immunity

Redness, swelling, heat, and pain are the four cardinal signs of inflammation. A fifth sign that is frequently added is

Loss of function

The type of immunoglobulin produced through intranasal vaccination is

IgA

When an animal receives a vaccine, about how long will it take before the animal's immune system will protect the animal from disease?

2 weeks

Excessive numbers of chylomicrons in blood can cause


-lipemia


-hemodilution


-leukopenia


-hemolysis

Lipemia

What cell is responsible for immunity against intracellular pathogens?


-T lymphocytes


-monocytes


-B lymphocytes


-plasma cells

T lymphocytes

External innate immunity depends on

Intact skin

An attenuated vaccine contains

Modified live virus

Which valves produce the second heart sound when they snap shut?


-aortic and mitral


-tricuspid and pulmonary


-pulmonary and aortic


-mitral and tricuspid

Pulmonary and aortic valves

The right atrium pumps blood into the

Right ventricle

Cardiac output is determined by

Stroke volume and heart rate

Another name for the left atrioventricular valve is the

Mitral valve

Chordae tendineae are found in the


-auricles


-ventricles


-interatrial septum


-atria

Ventricles

Which is true of the pulmonary circulation?


-it carries deoxygenated blood to the L atrium


-it operates at a higher pressure than systemic circulation


-blood coming from the pulmonary circulation enters the R atrium


-none

None

Arterioles are

Small muscular arteries

The _____ represents the strength of a heartbeat

Stroke volume

The mediastinum


-is the sac surrounding the heart


-contains the heart, thymus, and other structures


-is formed by an I folding of the parietal peritoneum


-is the space containing the heart and lungs

Contains the heart, thymus, and other structures

Systolic blood pressure measures


-the force by which blood is ejected from the left ventricle during systole


-the force by which blood is ejected from the right ventricle during systole


-the pressure remaining in the aorta during left ventricular diastole


-the pressure remaining in the aorta during right ventricular diastole

The force by which blood is ejected from the left ventricle during systole

The fibrous sac that enclosed the heart is the

Pericardium

The apex of the heart is made up of the

Wall of the left ventricle

Diastolic blood pressure is


-the pressure in the venous system


-the pressure in the arteries just before the ventricles contract


-the pressure in the arteries just after ventricles contract


-the average pressure in the arteries and veins

The pressure in the arteries just before the ventricles contract

Which chamber of the heart sends deoxygenated blood to the lungs for oxygenation when it contracts?

Right ventricle

The heart is located in the thoracic cavity in the space between the two lungs. This space is called the

Mediastinum

Which of these would slow heart rate?


-sympathetic stimulation


-increased vagus nerve activity


-release of epinephrine from the adrenal gland


-all of the above

Increased vagus nerve activity

Which vein can be used for venipuncture in nearly all species of animals?

Jugular vein

The ductus arteriosus in a fetus allows blood to flow


-directly into the ven cava from the pulmonary vein


-directly from the left atrium into the right atrium


-directly from the right atrium to the left atrium


-directly into the aorta from the pulmonary artery

Directly into the aorta from the pulmonary artery

What type of muscle is found in the middle layer of a muscular artery's wall?


-involuntary, striated muscle


-involuntary, nonstriated muscle


-voluntary, striated muscle


-voluntary, nonstriated muscle

Involuntary, nonstriated muscle

Which diagnostic test is typically required for identifying arrhythmia?

ECG

Identify this valve of the heart

Mitral valve

Blood found in this structure is oxygenated or deoxygenated?

Oxygenated

Blood found in this structure is oxygenated or deoxygenated?

Deoxygenated

Blood found in this structure is oxygenated or deoxygenated?

Oxygenated

Name the structure indicated in the picture

Pulmonary artery

The QRS complex on the ECG represents


-atrial depolarization


-ventricular repolarization


-ventricular depolarization


-nerve stimulation of the ventricles

ventricular depolarization

The dark bands seen in skeletal and cardiac muscle fibers are the

A bands of sarcomeres

The impulse created by the natural pacemaker of the heart travels

Across both atria-atrioventricular septum-interventricular septum-heart apex-heart base

Which of the following arteries is most commonly used to check the pulse on the cat?


-mandibular


-posterior digital


-coccygeal


-femoral

Femoral artery

The pulmonary circulation begins when deoxygenated blood passes through the ______ into the pulmonary circulation


-mitral valve


-tricuspid valve


-left semilunar valve


-right semilunar valve

Right semilunar valve

The largest elastic artery in an animals body is the

Aorta

Which of these is least likely to pass out of the capillaries and into the interstitial space?


-water


-calcium ions


-glucose


-albumin

Albumin

Cardiac muscle can generate its own contractions and relaxations and is therefore called

Autorhythmic muscle

The structures that make up the primary cardiac conduction, in order that the impulse travels through them, are the

SA node-AV node-bundle of His-Purkinje fiber system

Deoxygenated blood from the systemic circulation enters the heart at the

Right atrium

A heart murmur is a sound produced by

Turbulent blood flow

Onan ECG reading of one cardiac cycle, the contraction of the main mass of the ventricles is represented by

The R wave

The majority of exchange of gases and nutrients between blood and tissue takes place at the ______ level

Capillary bed

Contraction of a heart chamber is called

Systole

The ductus arteriosus


-is open in the fetus and closed in the adult


-is closed in the fetus and open in the adult


-allows blood to move from pulmonary vein to L atrium


-A & C

Is open in the fetus and closed in the adult

Oxygenated blood is carried from the mother to a fetus through the


-placental vein


-umbilical vein


-placental artery


-umbilical artery

Umbilical vein

The type of blood vessel that usually carries oxygenated blood away from the heart is a/an

Artery

The atria of the heart sit at the _____ of the heart

Base

Which one of the following arteries is most commonly used to check the pulse on a horse?


-coccygeal


-aorta


-mandibular


-carotid

Mandibular

Another name for the right semilunar valve is the

Pulmonary valve

The picture shows blood passing through the ________ valve

Pulmonary

This vessel carries deoxygenated blood away from the heart. This is the

Pulmonary artery

Name the structure indicated in the picture

Aorta

Name the structure indicated in the picture

Interventricular septum

Blood found in this structure is oxygenated/deoxygenated

Deoxygenated

Which type of blood vessel has one-way valves in its lumen?

Veins

Tricuspid valve stenosis results when the tricuspid valve

Doesn't open completely during a trial systole

When looking at a standing animal from the side, you would locate the heart

Between it's right and left olecranon processes

The impulse to begin each heartbeat of the heart comes from the

Sinoatrial node

The interventricular septum is a continuation of the

Interatrial septum

In domestic animals, the _______ of the heart rests on the sternum

Apex

Resting membrane potential in nerve cells, the skeletal muscle cells and cardiac muscle cells is maintained by

Sodium-potassium pump

The interarterial septum is a continuation of the

Myocardium

The membrane that lines the chambers of the heart is the


-endocardium


-myocardium


-pericardium


-epicardium

Endocardium

The largest vein in an animals body is the

Vena cava

The natural pacemaker of the heart is the

SA node

Osmosis


-causes solute to move down the concentration gradient


-requires a semipermeable membrane


-causes water to move from an area of low osmolarity to an area of high osmolarity

B and C

Which chamber of the heart sends oxygenated blood to systemic circulation when it contracts?

Left ventricle

A small amount of pericardial fluid is normally found in the pericardial space between

The visceral pericardium and parietal pericardium

The large blood vessel that brings deoxygenated blood from the systemic circulation is the

Vena cava

Which of these vessels carries oxygenated blood?


-caudal vena cava


-femoral vein


-pulmonary vein


-pulmonary artery

Pulmonary vein

What event is associated with the first heart sound?


- closing AV valves


-opening AV valves


-onset if diastole


-atrial depolarization

Closing AV valves

The outermost layer of the heart itself is the

Epicardium

The inner layer of a blood vessel is the


-epithelium


-endocardium


-endomysium


-endothelium

Endothelium

Name the structure indicated in the picture

Right ventricle

Name the structure indicated in the picture

Caudal vena cava

Name the structure indicated in the picture

Right atrium

Identify this structure of the heart

Interventricular septum

Name the structure indicated in the picture

Cranial vena cava