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65 Cards in this Set
- Front
- Back
why do we breath |
we need oxygen to do oxidative phosphorylation in the electron transport system. hydrogen combines with the oxygen to form H2O. Generates ATP |
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functions of respiratory system (6) |
move air to and from exchange surfaces of lungs, protect respiratory surfaces from outside environment (air conditioning), provide gas exchange between air and circulating blood through extensive surface area, produce sound, participate in olfactory sense, regulate co2 and hydrogen concentrations |
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upper respiratory tract |
nose, nasal cavity, pharynx, |
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lower respiratory tract |
larynx, trachea, bronchus, bronchiol, terminal bronchiole |
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conducting portion |
from nasal cavity to terminal bronchiole. this is where air is conditioned: warm, humidify, & cleanse |
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respiratory portion |
respiratory bronchiole and alveoli, this is where gas is exchanged |
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what type of epithelium is in the oral cavity |
stratified squamous epithelium |
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what type of epithelium is in the bronchioles to the terminal bronchiole |
columnar to cuboidal epithelium with cilia |
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mucosa |
a lining consisting of an epithelium and underlying connective tissue |
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where would you find pseudostratified columnar epithelium with cilia and goblet cells |
nasal cavity, paranasal sinuses, nasopharynx, trachea, main and lobar bronchi |
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where would you find simple ciliated columnar epithelium |
segmental bronchi and large bronchioles |
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where would you find simple ciliated cuboidal epithelium |
small terminal and respiratory bronchioles |
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where would you find simple squamous epithelium (no cilia) |
alveolar ducts and alveoli |
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thyroid cartilage |
also called adam's apple. made of hyaline cartilage |
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cricoid cartilage |
made from hyaline cartilage. forms posterior portion of larynx |
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epiglottis |
elastic cartilage that covers opening of trachea |
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functions of cartilage on larynx |
keeps respiratory system open and prevents food and liquid from entering respiratory system |
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vestibular fold |
superior fold (false vocal fold) respiratory epithelium covers sero-mucus glands function is to protect delicate vocal folds |
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vocal fold |
inferior to vestibular fold. called true vocal fold/ cord nonkeratinized, stratified squamous epithelium vocal ligament within vocal fold. function is to produce sound through vibrations |
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what is meant by air conditioning |
warmth is added through flow of blood in vessels, humidity is added through sero-mucous gland s& goblet cells, swell bodies help protect from dehydration, cleansing occurs where hairs and secretions and cilia and machrophages entrap foreign particles |
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bronchiole size from largest to smallest |
main bronchus, bronchiole, terminal bronchiole, respiratory bronchiole, alveolar duct, alveolar sac |
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the trachea is also known as the |
windpipe |
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trachea |
extends from larynx to mediastinum. branches into pulmonary bronchi, covered in tracheal cartilage 'C' rings which are elastic ligaments that help to strength, protect, and keep open airway |
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carina |
separate the right and left primary bronchi |
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what is the structural differences between the trachea, bronchi, and bronchioles |
trachea have cartilage plates, bronchi have small cartilage plates, bronchiole have no cartilage, but smooth muscle increases |
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the right lung has____ lobes and the left lung has __ |
3, 2 |
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hilum |
main bronchus, pulmonary artery, pulmonary veins |
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bronchodilation |
dilates bronchial airways through use of norepinephrine/ Beta 2 receptors. caused by sympathetic NS activation. to dilate, smooth muscle relaxes which reduces resistance
antihistamines fight or flight |
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bronchoconstriction |
rest and digest activated by parasympathetic ns smooth muscles constrict which leads to less airway histamine release (allergic reactions) |
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difference between pulmonary artery and bronchial artery |
pulmonary artery is deoxygenated, coming from the right ventricle and follows the bronchial tree all the way to the alveoli, gas exchange occurs with the alveolar capillaries
bronchial arteries carry oxygenated blood, come from a branch off of the aorta, provide oxygen and nutrients to tissues of conducting passageways of lungs & pleura, stops before the alveoli |
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bronchial veins vs. pulmonary veins |
pulmonary veins carry oxygenated blood from lungs into heart
bronchial veins carry deoxygenated blood used by the lungs back into the right atrium or into the pulmonary vein (which leads to mixing of deoxygenated and oxygenated) |
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asthma is caused by |
excessive stimulation of smooth muscle leading to bronchoconstriction |
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copd is caused by |
inflammation of the airways leading to narrowing of passageways or loss of alveolar walls creating fewer areas for gas exchange |
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fibrosis is caused by |
difficulty expanding/ contracting due to increased connective tissue |
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RDS is caused by |
lack of surfacant or insufficient type 2 pneumocyte function |
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type 2 pneumocytes |
secrete surfacant |
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terminal bronchiole epithelium |
cuboidal cells |
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respiratory bronchiole epithelium |
cuboidal cells interuppted by alveoli type 1 pneumocyts |
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where in alveolar epithelia is gas exchange most optimal |
thin areas- areas adjacent to capillaries |
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what to thick epithelial areas do |
they have more connective tissue and add structural support to alveoli |
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dust cells |
alveolar macrophages |
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type 1 pneumocyte |
forms most of the alveolar wall |
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which membrane secretes fluid and which resorbs fluid (parietal vs. visceral) |
parietal secretes, visceral resorbs |
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intrapleural pressure |
pressure in space between parietal and visceral pleura. averages about -4mmHg (756mmHg) and has a maximum of -18mmHg (742mmHg)
atmospheric pressure is 760mmHg so it is below this. intrapulmonary pressure in alveoli is similar to atmospheric 760 mmHg |
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external respiration |
air from the atmosphere to cells undergoing metabolism includes pulmonary ventilation (breathing), gas exchange across alveolar membrane, transport of O2 and CO2, gas exchange from systemic capillaries |
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how does the thoracic cavity move during inspiration and expiration |
during inspiration it expands and the sternum moves anteriorly (outward) and the diaphram contracts which pulls it down to increase size of thoracic cavity. ribs are elevated and throacic cavity widens during expiration the thoracic cavity compresses, the diaphragm relaxes and the thoracic cavity becomes smaller and ribs are depressed and sternum moves posteriorly |
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muscles during quiet breathing vs. forced inspiration |
external intercostal muscles extend during quiet breathing during forced inspiration- activates the accessory muscles of inspiration
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boyle's law |
P=1/V |
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pressure in pleural cavity and intrapulmonary pressure |
756 mmHg intrapleural and 760 mmHg in intrapulmonary without breathing, however, when air is inhaled, the intrapulmonary pressure drops to 759 mmHg and intrapleural pressure drops to 754 mmHg |
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about how often do we breath per minute and how much is breathed in per every breath |
~500 ml and 12-16 times per minute |
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compliance |
how easily the lungs expand and contract- depends on elastic fibers. it is a good indicator of expandability.
low compliance requires greater force and high compliance requires less force |
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factors that affect compliance |
connective tissue structure and level of surfacant and the mobility of the thoracic cage |
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elastic rebound |
when inhalation muscles relax, returning lungs and alveoli to original position |
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eupnea vs. hyperpnea vs. apnea |
eupnea is quiet breathing and it involves diaphragmatic breathing (deep breathing) and costal breathing (shallow breathing)
hyperpnea is forced breathing and it involves accessory muscles
apnea is when there isn't any movement of the muscles and the volume of the lungs remain unchanged |
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how does the respiratory system adap to changing oxygen demands |
varying the number of breaths per minute and the volume of air moved per breath |
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respiratory minute volume |
Ve amount of air moved per minute. calculated by the respiratory rate (f)x the tidal volume |
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anatomic dead space |
Vd only a part of respiratory minute volume reaches alveolar exchange surfaces. anatomic dead space is the volume of air remaining in conducting passages |
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alveolar ventilation |
amount of air reaching alveoli each minute. calculated as respiratory rate x (tidal volume- anatomic dead space)
Va= f x (Vt-Vd) |
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tidal volume |
amount of air one can move in or out of lungs in single respiratory cycle during normal resting conditions |
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inspiratory reserve volume |
amount of air one can take in over and above tidal volume |
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expiratory reserve volume |
amount of air one can voluntarily expel after completed normal respiratory cycle |
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residual volume |
amount of air remaining in lungs after maximal exhalation- minimal volume is the amount of air left if lungs collapsed |
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inspiratory capacity |
tidal volume+ inspiratory reserve volume |
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vital capacity |
maximum amount of air one can take into or out of lungs during forced exhalation and inhalation |
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total lung capacity |
total volume of lungs |