Alterations Of Hormonal Regulation

Front 1

Elevated Hormones (specifically ectopic) – What role does cancer play

Back 1

- Continues to produce the differentiated product, but does so in a manner that is largely independent of the normal regulatory processes

Front 2

Hypopituitarism – Cause and what occurs to the tissue as a result

Back 2

- Caused by pituitary infarction
- Tissue dies
- Most commonly caused by bleeding due to a non-cancerous tumor of the pituitary

Front 3

Acromegaly – Cause and effect of increased GH on the pancreas

Back 3

- Hypersecretion of growth hormone during adulthood
- Insulin resistant DM occurs when the pancreas cannot secrete enough insulin to offset the effects of GH

Front 4

Graves Disease – Cause and clinical manifestations

Back 4

- Stimulation of the thyroid with antibodies against the TSH receptor
- Goiter, opthamolpathy, pre

Front 5

Hypothyroidism – Causes and clinical manifestations

Back 5

- Congenital
- Defective hormone synthesis resulting from autoimmune thyroiditis endemic iodine deficiency or anti-thyroid drugs
- latrogenic loss of thyroid tissue after surgical or radioactive treatment for hyperthyroidism

Front 6

DM Type 1 – Cause of Islet cell destruction, clinical manifestations including DKA, treatment & diagnosis

Back 6

- Genetic susceptibility, autoimmunity, environmental factors
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Front 7

Cushing Disease/Syndrome – Causes and clinical manifestations

Back 7

- Disorders of the adrenal cortex causing hypercortisolism
- Weight gain, glucose intolerance, polyuria, glycosuria, muscle wasting, osteoporosis, renal stones, HTN, alteration in mental status