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19 Cards in this Set

  • Front
  • Back

Herpesviridae

most prevalent DNA viruses




enveloped, polyhedral, linear dsDNA, latent - never cured (hides in neurons)

Herpes virsus 1 and 2

Skin lesions




HHV1: cold sores/fever blisters/ whitlow




HHV2: genital herpes

Varcella zoster

HHV 3


Varcella (chicken pox)





Transmission: respiratory droplet, contact with blister secretions, fomites

Reactivation of Varcella zoster

Shingles




latent virus reactivates




S/S: cluster of vesicles along nerve paths in skin, mild itching to continuous severe pain

Epsein-Barr visues

HPP 4 - Infectious Mononucleosis (Mono)


Transmission: usually saliva


fever, sore throat, fatigue, swollen lymph nodes




Enters blood stream, invades B lymphocytes, becomes latent in B cells, Tc cells destroy infected B cells

Human papillomavirus

HPV- warts




Benign growths- skin, mucous membranes




*increased risk of cancer

Hepatitis A

Hepatitis




transmitted: fecal oral




S/S: jaundice, anorexia, abdominal discomfort, fever chills




self limiting-vaccine available

Hepatitus B

Hepatitis




Transmission: blood, semen




S/S: asymptomatic or mild symptoms, long term can cause severe liver damage- jaundice


vaccine available

Hepatitus C

Hepatitis


Transmission: blood, semen




Chronic - high mutation rate helps escape immune pressures, new treatment available


S/S: often few, fatigue, joint pain, belly pain, jaundice, dark urine


NO VACCINE

Hepatitus D

Requires Hep B to become virulent




Transmission: blood, semen




cirrhosis of the liver, liver cancer


HepB vaccine indirectly protects against HepD



Hepatitus E

Enteric hepatitus




Transmission: fecal/oral




S/S: mild infection except for pregnant women(mortality rate high in 3rd trimester)


NO VACCINE

Noroviruses (Norwalk-like)

Gastroenteritis




leading cause of "stomach flu" in adults




Transmitted: ingestions via contaminated food/water, fomites (billions in stool or vomit)




onset 24-48 hr after transmission, self limiting





Rubella virus

Rubella, aka German meseals




Transmission: respiratory droplet, highly contagious




S/S: rash, pink to red spots. Adults-arthritis or encephalitis. Can cross placenta-multiplies in embryonic cell. rubella-belly

HIV

Retro virus- has outer envelope


Transmission: blood, semen, saliva, vaginal secretions, breast milk


Destroy immune system- cells tagert T helper cells, dendritic cells, macrophages, smooth muscle cells




Aids is a syndrome CD4 count below 400

Measels virus

Rubeola/measels




S/S: Koplik's spots, Macular rash (white spots near molars), photophobia, headache, sore throat, dry cough


Rare complications: encephalitis, pneumonia




vaccine available

Mumps virus

Disease: Mumps




S/S: parotid glands enlarge, pain just below the air, infection of upper respiratory tract, then spread to other organs


Rare complications: meningitis, pancreatitis, inflammation of ovaries/testes


vaccine available



Ebola virus

(EVD) Filamentous virus


Transmission: direct contact with blood, secretions, bodily fluids


S/S: sudden onset fever, intense weakness, muscle pain, headache, sore throat, vomiting, diarrhea, rash, impaired kidney and liver function.


Mortality 90% depending on species



Influenza

Segmented genome (8 pieces)




Antigenic drift- small changes in virus


Antigenic shift- big changes in virus


Pandemic predicted

Incluenza A and B

Disease: influenza aka Flu




S/S: fever, malaise, headache, body aches,


-rarely attach cells outside the lungs


-infected epithelial cells killed




increase susceptibility to secondary infections