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73 Cards in this Set

  • Front
  • Back

What is tidal volume?

volume of air inspired or expired with each normal breath

What is functional residual capacity?

amount of air remaining in the lungs at the end of normal expiration

What is minute respiratory volume?

total amount of new air moved through the respiratory passage per minute

What is the formula for minute respiratory volume?

Tidal volume x Respiratory rate = Min. Resp Vol

By what 2 methods can lungs can be expanded & contracted?

•Contraction & relaxation of diaphragm


•Expansion & relaxation of the ribs

What is surfactant? Why is it important?

•A substance that is secreted by alveolar epithelial cells



•Helps to reduce the surface tension of the alveoli to prevent them from collapsing

When is surfactant produced in the fetus?



What effect will this have on premature neonates? Why?

•Late gestation



•Will have "respiratory distress" due to the alveoli filling with fluid, causing them to collapse

What is the ultimate goal of pulmonary ventilation?

To renew air in the gas exchange areas of the lung

What are the gas exchange areas of the lung? (4)

•Alveoli


•Alveolar sacs


•Alveolar ducts


•Bronchioles

What is dead space? How does age affect this?

•Respiratory area where no gas exchange occurs



•Increases

What does sympathetic stimulation of the respiratory tree do?

Causes bronchodilation through stimulation of beta-receptors

What does parasympathetic stimulation of the respiratory tree do?

Causes bronchoconstriction

What effect does Histamine have on the respiratory system?



When is it released?

•Causes bronchoconstriction (inhibits breathing)



•Released during allergic or anaphylactic reactions

What function does respiratory cilia serve?

Ciliated epithelium beat in an upward motion to remove mucus and debris from the respiratory tree to the pharyngeal area

What function(s) does the mucous coat serve?

•Keeps the respiratory tract moist


•Traps small inhaled particles for removal

What are the 3 components of pulmonary circulation?

•Pulmonary arteries


•Pulmonary veins


•Pulmonary capillaries

Where can you find the pulmonary arteries?


What do they do?

•Carry de-oxygenated blood out of the right ventricle

What do the pulmonary veins do?

Transport re-oxygenated blood from the lungs into the left ventricle

What goes on in the pulmonary capillaries?

Gas exchange occurs

Explain the principles of gas exchange?

*

What are some factors that affect the rate of gas exchange through the respiratory membrane?

Membrane thickness

How does membrane thickness affect the rate of gas exchange?



The membrane can thicken because of _____ or ________

•As membrane thickness increases, rate of exchange decreases



•Edema, fibrosis

Blood is ___% saturated with oxygen when it leaves the lungs to the left atrium

98%

What is the role of hemoglobin in oxygen transport?

Carries almost 97% of oxygen that is diffused into the blood

When O2 pressure is ____ in pulmonary circulation, it will rapidly bind to Hbg.

high

When O2 concentration is ____ at the tissue level, oxygen is released from Hgb.

low

Where is nervous regulation of the respiratory rate located?

in the brain stem

T/F: Excess CO2 stimulates the respiratory center causing a decrease in respiration rate and an increase in strength of inspiration

False - It will not only cause an incr. in the strength of inspiration, but in RR too

What Chronic Obstructive Pulmonary Disease (COPD)?



What causes it?



•Chronic hypersensitivity of bronchioles to an allergic substance

What reactions result from having COPD? (4)



Which one is more commonly seen advanced cases? Say your answer in an accent.

• Mucus secreted into bronchiolar airway


• Bronchiolar smooth muscle spasm


• Edema in walls of bronchioles


• Fibrosis of bronchiolar airways*

What are the two causes of pulmonary edema? What does each one do?

•Left heart failure or mitral valve insufficiency -> results in an incr pulmonic capillary pressure


•Pulmonary edema = fluid filling the pulmonary interstitial space

What is dyspnea?

Difficulty breathing

What are the 6 components of the renal system?

•Kidney


•Urethra


•Ureters


•Urinary bladder


•Renal arteries & veins


•Adrenal glands

What is the function of the nephron?

to clear the blood of unwanted substances as it passes through the kidney

What is Polyuria?

Increase in the volume of urine

What is polydipsia?

Increase in thirst

What is the most common sign of kidney disease?

PU/PD

The kidney is composed of approximately 2 million urine producing units called ________

nephrons

Each nephron is made is up a filtering unit called a __________, where fluid is filtered from the blood

glomerulus

From the glomerulus, where does the filtered blood go and what is happening to it?

Goes to a long tubule where filtered blood will be made into urine

Fluid filtered into the glomerulus is collected into the tubule system where ____% of water will be reabsorbed into the bloodstream

99%

T/F: Even though kidney has a fluid by-product, it actually conserves body water

True

What are unwanted substances/end products of metabolism are removed by the kidneys, from the body?

•Creatine


•Chemicals & drugs


•Urea (ammonia) created from protein metabolism


•Uric acids


•Ions


•Na, K, Cl, H, & Ca

What species is uric acid commonly seen in?

birds

Which chemical elements are filtered and re-absorbed into the bloodstream? (3)

•Chlorine (Cl)


•Sodium (Na)


•Calcium (Ca)

Which chemical elements are filtered and excreted from the body? (2)

Potassium (K) and Hydrogen (H)

______, ________, and _____ _____ are highly re-absorbed in the tubular system

Glucose, proteins, & amino acids

T/F: Because urea and creatine are always re-absorbed, they are found in low concentrations within the urine

False - urea & creatine are highly concentrated in the urine because they are poorly re-absorbed

Which ions are re-absorbed?

Sodium (Na) and Calcium (Ca)

Which ions are excreted?

Potassium (K) and Phosphate (PO4)

What causes diluted urine?


Why does this happen?

•Excess water excreted from kidneys



•Because body fluid solute concentration is too low & body fluids are too dilute

What causes concentrated urine?

Kidneys absorb water when body fluids are too concentrated

What are the two types of renal disease?

Acute Renal Failure and Chronic Renal Failure

What causes Acute Renal Failure (ARF)?

Rapid destruction of kidney tissue from infectious agents or chemical toxins


(ex: antifreeze, leptospirosis)

What causes Chronic Renal Failure (CRF)?

Results from chronic scarring of kidneys

What is the importance of alcohol dehydrogenase?

Naturally found in the animal; when the animal consumes antifreeze, the dehydrogenase will turn it into a crystal and will block the nephrons which will cause ARF - complete kidney shutdown

Clinical signs of ARF? (3)

•No urine output


•Severe depression from acidosis & back-up of toxins


•Death if not corrected quickly

What are some signs of CRF?


What is the number one signs of CRF?

•Excess urea & creatine in blood


•Diluted urine due to reduced re-absorption of water from the diseased tubule


•PU/PD

What is important to know about CRF?

It takes months to develop outward signs because only 35% of nephrons are needed for normal body function

When do the kidneys shut down?

When nephrons go below 5%

Treatment of CRF?

•Fluid diuresis (forcing patient to urinate)


•Protein reduced diet

What 2 functions does the bladder serve?

•Threshold pressure (sensory response)


•Nerve reflex (motor response) constricting the bladder and expelling urine

T/F: The bladder has an involuntary sphincter muscle

False - voluntary sphincter muscle

What are the different types of bladder abnormalities?

•Bladder Infection


•Urinary calculi (bladder stones)


•Feline Lower Urinary Tract Disease (FLUTD)


•Urinary Incontinence


•Bladder Atony

What is urinary incontinence? Who does it affect? What are the signs? What is the Tx?

•In older spayed females due to lack of estrogen



•Uncontrolled dribbling


•Leakage through weakened sphincter



•DES - aids to control smooth muscle sphincter

What is bladder atony? What are some signs? How does this occur?

•Disruption in nerve pathway due to blunt force trauma to bladder or spinal cord



•Over-distention (dribbling)



•Can occur through damage to the spinal cord or through abdominal trauma leaving them unable to control their bladder

Who does bladder infection affect most?


What are the clinical signs?


What is the treatment?

•Females because of their shorter urethra



•Straining to urinate


•Blood in urine (hematuria)



•Antibiotics and urine acidifiers

What purpose do urine acidifiers serve?


give an example

1) Kill bacteria


2) Reduce stone formation



example: Ammonia Chloride

What is urinary calculi?


What causes it?


What are the clinical signs?


Tx?

•Bladder stones



•Improper nutrition - most common


•Breed disposition (ex: Dalmatian & Schnauzer)



•Blood in urine


•Straining to urinate


•Palpable stones



•Small stones may be dissolved w/ special diets


•Stones may return if not properly managed

What is FLUTD?


Who does it affect?


What are the clinical signs?

•Formerly known as "Feline Urologic Syndrome"



•Obstruction of urethra due to entrapped mineralized protein material


•Common in over-weight, neutered males



•Straining to urinate w/ no urine production

What is the treatment for FLUTD?

•Urinary catheterization


•Fluid therapy

How can FLUTD be prevented?

•Control of diet


•Multiple factor disease -> over-weight, length/width of urethra

Complete obstruction of FLUTD may lead to (3):

•Back-up of toxins


•Depression/vomiting


•Death if obstruction is not relieved