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46 Cards in this Set

  • Front
  • Back
Bugs that do not Gram Stain
Treponema, Rickettsia, Mycobacteria, Mycoplasma, Legionella, Chlamydia

(These Rascals Might Microscopically Lack Color)
1. Bacterias makes IgA protease
2. Transformation of genetics
3. Encapsulated bacteria
S. pneumoniae, H. influenzae, Neisseria
(SHiN)
Endotoxins produced by?
Gram -s and Listeria
How to differentiate between Coagulase - Staphylococcus?
Novobiocin
S. saphrophyticus: resistant
S. epidermidis: sensitive
(on the STAPH retreat, there was NO StRES)
How to differentiate between alpha-hemolytic strep?
Optochin
Viridans streptococci: resistant
S. pneumoniae: sensitive
(OVRPS- "overpass")
How to differentiate between beta-hemolytic strep?
Bactracin
Group B: resistant (S. agalactiae)
Group A: sensitive (S. pyogenes)
(B-BRAS)
- Virulence Factor is Protein A
- Inflamm Disease: skin infections, organ abscesses, pneumonia
- Toxin Disease: TSS, scalded skin syndrome, rapid-onset food poisoning
- Causes acute bacterial endocarditis, osteomyelitis
S. aureus
- Most common cause of: Meningitis, Otitis media, Pneumonia, Sinusitis (MOPS)
-"rusty" sputum
-sepsis in SCA and splenectomy
S. pneumoniae
(s. pnuemoniae MOPS are Most OPtochin Sensitive)
Streptococcus that causes subacute bacterial endocarditis?
S. sanguis (sanguis=blood)
This bacteria causes:
- pharyngitis, cellulitis, impetigo (pyrogen)
- scarlet fever, TSS (toxin)
-RF, acute glom. nephritis (immuno)
S. pyrogenes (has M protein)
Clinical presentation of RF?
Sq plaques, Polyarthritis, Erythema marginatum, Chorea, Carditis
(No "rheum" for SPECCulation)
- In gut
- Can cause bacteremia and subacute endocarditis in colon CA pts.
Streptococcus bovis (group D)
- Sx: pseudomembranous pharyngitis with lymphadenopathy
- Gram + rods
- ADP ribosylates EF-2 to - protein synthesis
Corynebacterium diphtheriae
(ABCDEFG: Adp ribosylation, Beta-phage, Coryn., Diptheriae, Ef-2 Granules)
-Gram +, spore-forming rod
-1. causes tetnus
-2. - Ach release--> botulism, floppy baby syndrome b/c spores in honey
-3. Causes gas gangrene and hemolysis
-4. Causes pseudomembranous colitis 2nd to antibiotics (clindamycin and ampicillin)
Clostridia
1. C. tetani (TETanus is TETanic paralysis)
2. C. botulinum (BOTulinum is from bad BOTtles of food and honey- causes flaccid paralysis)
3. PERFringens PERForates a gangrenous leg)
4. DIfficle causes DIarrhea
-Gram + spore forming rod
1. Skin: painless black ulcer
2. Lung: flu--> pulm hemorrhage, mediastinitis, and shock (Woolsorter's disease)
Bacillus anthracis
(edema factor)
-Gram + bacteria with endotoxin
-Moves from cell to cell
-Causes: septicemia, neonatal meningitis, mild gastritis, etc
Listeria monocytogenes
-Two Gram + rods with branching filaments:
1. In oral cavity; abscess can drain to face
2. Causes pulm infections in immuncomp pts
-How to treat
-1. Actinomyces israelli
2. Nocardia asteroides
-Sulfa for Nocardia; Actinomyces use Pcn (SNAP)
Sx are: fever, night sweats, weight loss, and hemoptysis
TB (Mycobacteria tuberculosis)
-Acid-fast bacteria
-CP: loss of eyebrows, nasal collapse, lumpy earlobe
M. leprae
(Two form lepromatous (lethal) and tuberculoid)
Lactose fermenting bacteria?
Citrobacter, Klebsiella, E. coli, Enterobacter, Serratia
(Lactose is the KEE, see on maConKee agar)
Gram negative cocci?
What so they ferment?
Neisseria
N. meningitidis: glucose and maltose
N. gonorrhoeae: glucose
(MeninGococci ferment Maltose and Glucose. Gonococci ferment Glucose)
-Causes Epiglottitis, Meningitis, Otitis media, and Pneumonia
-Gram - coccobacillary rod
-Chocolate agar
haEMOPhilus influenzae
-Legionnaires' disease= pneumonia and fever
-Pontiac fever= mild flu
-Gram - rod
-Silver stain
-Charcoal yeast agar (Fe & cysteine)
Legionella pneumophila
"French legionnaire (solider) with sliver helmet, sitting around campfire (charcoal) with his iron dagger-he is no sissy (cysteine)"
-Gram - rod
-Non-lactose fermenting, oxidase +
-Assoc w: Pneumonia, Sepsis, External otitis, UTI, Drug use, Diabetic Osteomyelitis
PSEUDOmonas aeruginose
(AERuginos=AERobic)
-Gram - rods
-Ferment glucose, oxidase -
-Capsular
-O ag
Enterobacteriaceae
(COFFEe: Capsular, O ag, Flagellar Ag, Ferment glu, Enterobacteriaceae)
-Gram - rod
-Cause: cystitis, pyelonephritis, pneumonia, neonatal meningitis, septic shock
E. coli
Klebsiella 4 A's?
Aspiration pneumonia
Abscess in lungs
Alcoholics
di-A-betics
-Gram - rod, non-lactose fermenting bacteria
- Both invade and cause bloody diarrhea
Salmonella (motile and disseminate) & Shigella
Sxs: Fever, diarrhea, HA, rose spots on abdomen
Typhoid fever (Salmonella typhi)
Common in day care centers.
Mimics Crohn's or appendicitis
Yersinia enterocolitica
Spirochetes
Borrelia, Leptospira, Treponema
(BLT)
-CP: Bell's palsy, Arthritis, Kardiac block, Erythema migrans
Lyme disease (Borrelia burgdorferi)
-in Ixodes ticks
1. Bug of syphilis
2. Causes yawns: infection of skin bones, and joints--> healing with keloids--> sever limb deformities (in tropics)
1. Treponema pallidum
2. Treponema pertenue
Stages:
1. Painless chancre
2. Maculopapular rash (palms and soles), condylomata
3. Broad-based ataxia, + Romberg, Chacot joints, stroke w/o HTN
Syphilis
(Tx: PCN G)
Baby w: Saber shins, saddle nose, CN VIII deafness, Hutchinson's teeth, mulberry molars
Congenital syphilis
VDRL false + with?
Viruses
Drugs
Rheumatic Fever
Lupus abd Leprosy
Bug of Cat Scratch Fever?
Bartonella ssp.
-Rod
-CP: gray vaginal discharge with fishy smell; nonpainful
Gardnerella vaginalis
(I don't have a CLUE why I smell FISH in the VAGINA garden.)
Classical triad: HA, fever, rash (vasculitis)
Rickettsiae
(Tx: tetracycline)
Rickettsial rashes?
1. R. rickettsii
2. R. typhi
1. rickettsii starts on hands and feet
2. typhus starts central and spreads outward
(Rickettsia on the wRist, Typhus on the Trunk)
Bug of Q fever?
Coxiella burnetii
Bugs that present with rash of palm and sole?
Coxsaxkievirus A
Rocky mountain spotted fever
Syphilis
(you drive CARS with you palms and soles)
- Obligate intracellular bug
- Elementary body (Enfectious and Enters cell)
-Reticulate body (Replicates by fission)
Chlamydiae
(tx: erythromycin or tetracycline)
Causes: reactive arthritis, conjunctivitis, nongonococcal urethritis, PID
Chlamydia trachomatis
(Can't see can't pee can't climb a tree.)
Chlamydial causes of atypical pneumonia?
C. pneumoniae
C. psittaci
-Causes walking pneumonia (slow onset, HA, nonprod. cough, diffuse interstitial infiltrates)
-No cell wall
-Membrane has cholesterol
Mycoplasma pneumoniae
(Tx: tetracycline or erthromycin)