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46 Cards in this Set

  • Front
  • Back

Cancer statistics

2nd cause of death in US.


Kid infected=worse(faster cell growth).


50% is preventable.

What is cancer?

Abnormal, uncontrolled growth of cells

What is a tumor?

Mass of tissue, serves no physiological function.

Benign tumor

Group of cells enclosed in a membrane, doesn't spread

Malignant tumor

Group of cells, invade other body parts


Blood vessels lymphatic system nerves

How does cancer spread?

1. Altered genetic activity of cell. Grows divides where shouldn't

Hyperplasia

Rapid growth of abnormal cells

Dysplasia

Abnormally shaped cells

In situ cancer

Continued abnormal growth, stay contained

Invasive cancer

Malignant, invades other tissues or sheds cells into blood stream

Spread of cancer least to worst bad

Altered cell, hyperplasia, dysplasia, in situ cancer, invasive cancer

Primary tumor

Original cancer location

Metastasizing

Traveling and seeding process of cancer cells

Metastasis

New tumors are called secondary tumors

Stresses of cancer

0- early, present in cells, rare


1- extensive with increased numbers


2- greater tumor size, degree of spreading still capsulated


3- spread to adjacent areas


4- advanced, spread to organs, difficult

Carcinoma

Common, skin breast uterus prostate lung internal organs

Sarcoma

Painful, muscle bone cartilage

Lymphoma

Spinal tap, lymph glands

Leukemia

In blood cells, increase in white blood cells, flu like symptoms

Cancer in men

Prostate c is common


Lung is most deadly


Brain or pancreatic is most aggressive

Cancer in women

Breast is common


Lung is most deadly

Old cancer survival rate

66% For 5 years

What % of skin and lung cancer could've been prevented?

90% skin 87% lung

Lung cancer

Most common cause of death in US


Tobacco causes 87% of preventable deaths


5yr survival rate is 15%

Colon and rectal cancer

3rd common for men and women


Risk factors: age over 50, diet, genetic predisposition

Breast cancer

Most common in women, not as fatal


Risk factors: over 50, diet, early menstruation, kid after 30


Detection: start looking at 20, mammogram at 40


Treatment: ultrasonagrphy, 98% survival rate if early

Prostate cancer

Most common in men, 2nd leading cause of death


Risks: age, diet, genetics


Detection: psa blood test, ultrasound


Treatment: surgery, 100% survival rate

Cervical cancer

Most from HPV, unprotected sex, smoking increases chance


20-30yrs old


Prevention: pap test in women 18-65, gardasil

Uterine or endometrial cancer

Women after 55


Risks: to much estrogen, no pregnancy, obese


Detect: pelvic exam, ultrasound of ovaries


Treatment: surgery, remove ovaries, chemo

Skin cancer

Most common form in US


Risk: uv rays, sunburn, white people 10X


Types: basal, squamous, melanoma


Treatment: ABCD

Melanoma

Deadly skin cancer

ABCD test

Asymmetry- cut in half, it's not the same


Border- irregular


Color- dark brown black multiple colors


Diameter- bigger than pencil eraser

Oral cancer

Lip tongue from tobacco use alcohol hard to cure

Testicular cancer

Rare, men 20-35

Role of DNA in cancer

23 pairs of chromosomes


Gene is a smaller unit of DNA

Mutagenes

Radiation, viruses, chemical substances cause

Oncogenes

Genes that transform a normal cell into cancer

Tumor suppressor genes

Type of oncogene that restricts cell growth

Why use tobacco?

Physiological addiction, social, psychological.


Secondary reinforces that trigger urge

Genetic factors that cause smoking

CYP2A6- enzyme that metabolizes nicotine, increases addiction


DRD2- gene associated with dopamine when you smoke, decrease addiction

How does nicotine affect brain?

Affect brain chemistry:


Release off neurotransmitters and hormones like epinephrine, dopamine

Nicotine on CNS

Increase HR, BP, enhance alertness


Mild sedative, relieve anxiety

Nicotine use among kids

90% of new smokers in US


13 average age, 10 age for chew


More likely to use if in environment

Emphysema

Tar on lung, tart kills lungs

Carcinogens in cigarettes

Nicotine causes cancer, 43 chemicals linked to cancer, additives, poison like arsenic


Carbon monoxide which displaces oxygen in red blood cells to not bind to oxygen

Cardiovascular disease linked to nicotine

Atherosclerosis: narrowing of arteries


Angina pectoris: chest pain


Myocardial infraction: heart attack


Long term:


Aortic aneurysm: bulge in aorta caused by weakening of walls


Pulmonary heart disease: right side of heart caused by damages to blood vessels of lungs