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17 Cards in this Set

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Amiodarone


· Whorl keratopathy


· Anterior subcapsular effects – causes


deposits


· Drug-induced intracranial HTN


(pesudotumorcerebri)


· Optic neuropathy/optic atrophy


Chloroquine/hydroxychloroquine (Plaquenil)


· Whorl keratopathy


· Cycloplegia


· Affect retina – Bull’s eye maculopathy


· Affect VF


Tamoxifen


· Whorl keratopathy


· Affects retina – white or yellow crystallinedeposits (commonly in macula) with or without macular edema


Corticosteroids


· Affect cornea – delayed wound healing


· PSC


· Blue sclera


· Increase IOP


· Drug-induced intracranial HTN


(pseudotumorcerebri)


Sildenafil (Viagra)


· Conj/Lids – subconj hemorrhage, conj


hyperemia


· Affects optic nerve – nonarteritic ischemic optic neuropathy


· Color vision


Sulfonamides


· Conj/Lids – Stevens-Johnson syndrome, lid edema


· Cause myopia


· Uveitis


· Optic neuritis


Digitalis


o Dyschromatopsia, including yellow or blue tingeto vision and/or colored halos


o Colored spots surrounded by coronas


o Snowy, hazy or blurred vision


o Dimming of vision


o Flickering or flashes of light


o Glare sensitivity


Tamsulosin (Flomax)


· Sclera/Uvea – intraopterative floppy irissyndrome


Bisphosphonates (Fosamax)


· Uveitis



Minocycline (tetracyclines)


· Blue sclera


· Drug-induced intracranial HTN


(pseudotumorcerebri)


· Tetracycline can cause pigmented cysts on conj


Drugs that Increase tear secretion


· Drugs that Increase tear secretion


o Adrenoceptor agonists


o Cholinergic agonists


o Antihypertensive agents


o Antineoplastic agents




· Drugs that decrease tear secretion


o Anticholinergics


o Antihistamines


o Beta Blockers


o Antidepressants


o Phenothiazines


o Hormone therapies


o CNS stimulants


o Diuretics


o Isotretinoin (Accutane)


o Antianxiety agents


o Chemotherapeutic agents


Know the drug categories that can causemydriasis/miosis


· Drugs that can cause Mydriasis


o Anticholinergics


o Antihistamines


o Phenthiazines


o CNS stimulants


o CNS depressants




· Drugs that can cause Miosis


o Opiates


o Antichoinesterases


Know the drug categories that can cause affectEOMs and eye movements


· Nystagmus


· Diplopia


· Smooth pursuit impairment


· Oculogyric crisis


Know which drugs/categories can cause myopia


· Sulfonamides


· Diuretics


· CAIs


· Isotretinoin (Accutane)


· Topiramate (sulfa-containing)


What do we need to know about herbal supplements

Know that herbal and nutritional supplements cancause ocular side effects but usually at higher dosages.


What do we need to know about ginkgo biloba


Know ginkgo biloba inhibits platelet aggregationso can interact with blood-thinning agents such as aspirin and warfarin.




· Spontaneous hyphema and retinal hemorrhage


· Inhibits platelet aggregation so should be usedwith caution in patients already using blook-thinning agents such as ASA and warfarin


Niacin

· Potential s/e


o Blurred vision


o CME


o DE


o SPK


o Discoloration of the eyelids


o Eyelid edema


o Loss of eyebrows and eyelashes