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38 Cards in this Set

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Cellulitis organisms

Group A strep, Staph aureus, H. influenza

Cellulitis involves which layer(s) of the skin

Epidermis + dermis

Treatment cellulitis

Antibiotics, I +D

Pathogen causing Erysipelas

Group A strep

Which area on the body is Erysipelas seen most?

Legs > face

Treatment for erysipelas

Penicillin G

Skin abscess organism

Staph aureus

Treatment skin abscess

I + D... add antibiotics if cellulitis gets involved

What is a felon?

Infection of the distal pulp spaces of the fingers

WHO AM I: Infection of the skin over the mantle of the nail or of the lateral nail fold

Paronychia

4 components to Kanavel's sign

1) Finger held in mild flexion


2) Fusiform swelling


3) Tenderness along tendon sheath


4) Pain with passive extension

In which infection do you see Kanavel's sign?

Tenosynovitis

Bacteriology of necrotizing infections

Polymicrobial! Rarely a single organism (except for GAS)

Most frequent spontaneous site of NI

Perineum

Most frequent overall site of NI

Limbs

Gold standard diagnostic tool for NI

Tissue biopsy

Bacterial synergistic gangrene includes the skin and soft tissue, but not the _________

Fascia

Necrotizing fasciitis includes the skin, soft tissue, fascia, but not the ___________

Muscle

Most common surgical management of Necrotizing fasciitis

Debridement

Organism that is an exotoxin A "super antigen"

Group A strep

Clostridial cellulitis is a slow progressive infection of the soft tissue, sparing the ________________

Muscle

2 pathogens that cause Clostridial cellulitis

1) C. Perfringes


2) C. Sprogenes

Clostridial Myconecrosis is an infection involving the dermis, fascia, and muscle, but sparing the _____________________

Epidermis

Which infection is associated with "mousy smell"?

Clostridial myconecrosis

Which infection is associated with crepitus in the subcutaneous tissue?

Clostridial cellulitis

Treatment of Clostridial myconecrosis?

Rapid debridement

Most reliable imaging modality to diagnose intra-abdominal infection

CT scan

Infection + SIRS = ?

Sepsis!

Infection is the _________, while sepsis is the __________

Process, response

T or F, SIRS can be caused by an infection

FALSE

In SIRS and Sepsis, 2 critical pathophysiological events

1) Decreased peripheral vascular resistance (increased permeability of capillaries, hypotension)


2) Decreased oxygen extraction (metabolic acidosis, cellular damage)

3 D's to source control an intra-abdominal infection

1) Drainage


2) Debridement


3) Definitive measures

How to diagnose Appendicitis?

Clinical symptoms mostly

Gold standard treatment for appendicitis?

Appendectomy

Aside from appendectomy, what else can we use to treat appendicitis?

Antibiotics. Mostly for complicated ones... but also for uncomplicated

Microbiology of intra-abdominal infections: gram negative bacterias are associated with _________, while anaerobes are associated with _________

1) mortality


2) abscess

Why is the outcome of an intra-abdominal infection variable?

Genetic predisposition

What are the most commonly used variants that explain the genetic variability between patients who are infected with the same pathogen?

SNPs = single nucleotide polymorphisms