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9 Cards in this Set
- Front
- Back
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snRNP what is its function what does the name represent who syn them and where |
small nuclear ribonucleoprotein they are synthesized by RNA polymerase 2 in the nucleus. they help remove introns form the RNA transcript nand are thus necessary for synthesis of mRNA |
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what metabolic process occurs in the cytoplasm and in the mitochondrial |
cytoplasm pentose phosphate pathway mitoc b-oxidaton of ffa ketogenesis TCA parts of urea CPS1 and ornithine transcarbamoylase pyruvate carboxylation |
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older person with lactic acidosis w pnemonia what will this lead to |
septic shock dt tissue hypoxia which will lead to oxidative phosphorylation and the shunting of pyruvate to lactate following glycolysis. |
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elderly pt with dementia or hemiparesis who presents signs of pneumonia may also present with what what will you see on the xray |
dysphagia which is a risk factor for aspiration pneumonia. dependent lung consolidation commonly seen in aspiration pneumonia |
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nitrites and oxidizing agents will bind and serve as tto for what |
cyanide poisoning dt its ability to cause methemoglobinemia |
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aldose reductase converts glucose into sorbitol which futher metabolise to what |
fructose by sorbitol dehydrogenase |
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cori dz |
debranching enz def (cori dz) leads to accumlationof glycogen with abn short outer chains (limit dextrins) dt inability to degrade alpha 1,6 glycosidic branch points. pt present w hypoglycemia ketoacidosis hepatomegaly mus wk hypotonia |
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explain the kozak sequence what happens when you have a mutation that changes guanosine for cytosine three bases upstream from the start codon (AUG) |
plays a role in the initiation of translation (mRNA binding to ribosomes) this is associated with thalassemia intermedia and will affect the kozak sequence |
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a mutation in the kozak sequence of the beta-globin gene is associated with thalassemia intermedia, which results in |
hypochromic, microytic |
