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180 Cards in this Set

  • Front
  • Back
What are the obstructive lung disorders?
-asthma
-emphysema
-chronic bronchitis
-cystic fibrosis
-bronciectasis
-bronchiolitis
Asthma is characterized by variable _____ _____ airflow obstruction and airway/bronchial ______________.
reversible expiratory
hyper-responsivenss
Asthma is generally allergen-induced immunologic responses by _____________.
several chemical mediators
Flow volume loops for obstructive disease are affected on ______. FEV1 is less than of equal to _____% of predicted.
expiratory
60
The degree of reversilbility, increased airway hyper-reactivity and after admin of bronchodilators you will see a 12% or greater increase in FEV1 and 200 ml increase in Peak expiratory flow rate are the things that make...?
asthma different from chronic bronchitis
Preop Assessment for Asthma...
-what is your breathing baseline and how is your breathing now?
-current clinical symptoms, last exacerbation, infections?
-medication regimen
-comparison and review of PFTs
-exercise tolerance?
-sputum at baseline and what is it currently?
-last time presented to ED and last time received systemic steroids?
-benefit to stop smoking 8 wks preop
-thorough chest auscultation
smoking cessation is beneficial to surgical pts greater than ____ weeks preop but not any sooner.
8 weeks
Preop laboratory studies for asthma?
-CXR: for baseline, signs of infections, severity of dx
-FEV1 or PEFR to assess severity of dx
-Full PFTs
-Baseline ABG
-Perhaps EKG to assess right heart failure
an additional dose of ____ and _____ ____ may be given just before induction (inhalers and systemic corticosteroids)
ipratropium and beta agonist
You should avoid giving an ___ ______ before anesthesia for the risk of bronchospasm. Consider using non pariculate antacid such as bictra or reglan.
H2 blocker
Asthma can be managed preop by Leukotriene inhibitors like ______, beta adrenergic agonists like _____-_____ or anticholinergic drugs like ______-____
singulair
salmetrol-serevent
tiotropium-spiriva
_____ is classified as a histamine blockers.
chromolyn
Chromolyn works by suppressing the secretory response of ___ ____ reaction
IgE-Antigen
Chromolyn is effective only in _____ ___ not basophils.
mast cells
How is chromolyn deliverd?
only by inhalation
Chromolyn can only be used ______ and is ineffective following histamine release.
prophylactically
Examples of inhaled corticosteriods are?
Beclomethason (QVAR)
Tramicinolone (Azmacort)
Fluticasone (Flovent)
The PO corticosteroid most given is _____. It can cause hypothalmic pituitary adrenal suppression so if the pt has received it in the last ____ months give Solucortef 100mg preop.
prenisone
6
Corticosteriods have __________ effects on the bronchial mucosa. Stabilize ____ cell membranes. Decrease airway ________. Controls chronic symptoms and prevents ______.
-anti-inflammatory
-mast cell
-hyper-responsiveness
-exacerbations
Cysteinyl-lekotriene (CysLT1) antagonist is a?
leukotriene inhibitor
Cysteinyl-lekotriene (CysLT1) competitively blocks ______ __ from binding to the receptor. Examples of this are Zafirlukast, montelukast and pranlukast.
leukotriene D4
Leukotriene inhibitors also inhibit the conversion of ______ acid to leukotriene A inhibiting the generation of leukotrienes. An example is Zileuton.
arachidonic acid
____ is a good induction choice for asthmatics because it bronchiodilates but a downfall is that it also increases secretions.
ketamine
both ____ and ____ are good choices for induction in an asthmatic because they bronchodilate and don't release histamine.
etomidate and propofol
the ____ form of propofol dose contain sulfites so this should be avoided in an asthmatic.
generic
the neuromuscular relaxants that release histamine and should be avoided in an asthmatic are?
succinylcholine and atricurium-dose and speed dependent
(curare, mivacurium)
Regarding pain management in an asthmatic; ____ should be avoided due to histamine release but fentanyl and analogues are okay to use.
morphine
avoid ____ and ____ in asthmatic related to prosteglandin decrease.
ketorolac and NSAIDs
All volatile anesthetics are potent _____ but _____ and ____ may irritate the airway.
bronchodilators
iso and des
reversing neuromuscular blocking agents is not a problem in the asthmatic because _____ are always given with the reversal which is an anticholinesterase.
anticholinergic
the most critical time intraop is?
airway instrumentation
Although regional anesthesia may decrease the risk of airway induced bronchospasm, a high spinal may aggravate ______ by blocking sympathetic tone (T1-T4)
bronchoconstriction
What are the goals of induction in the asthmatic patient?
-achieve deep anesthesia before airway manipulation and surgical stimulation
-avoid histamine releasing drugs
-avoid bronchospasm
Again, the agents to avoid in an asthmatic are?
-morphine
-atracurium
-mivacurium
-meperidine
-succinylcholine (sometimes ok to use)
administering ipratropium and a beta 2 agonist just before ____ help to reduce bronchospasms.
induction
1-1.5mg/kg IV of ______ can also help to reduce bronchospasm.
lidocaine
Some things to think about for differential diagnosis for wheezing...
-foreign body
-partially blocked/kinked ETT
-light anesthesia
-aspiration
-endobronchial intubation
-tension pneumo
-pulm embolism
-pulm edema
-acute exacerbation of asthma
-anaphylaxis
What is the first step of management for an OR emergency related to asthma?
deepen your anesthetic agent and 100% FiO2
What is the second step of management for an OR emergency related to asthma?
-auscultate the chest
-verify the problem is bronchospasm
-check patency and position of ETT
What is the third step of management for an OR emergency related to asthma?
-admin medications
-b-adrenergic agnosits
-iv hydrocortison (1.5-2mg/kg
-epi (0.1mcg/kg bolus)
-aminophylline
for emergence of an asthmatic giving 1.5-2mg/kg of ____ may help to blunt airway reflexes
lidocaine
_______ is the most common pulmonary disorder and it effects more men then women.
COPD
COPD is the loss of elastic recoil of the lung due to destruction of the lung ____. This leads to the collapse or airways during ____, leading in turn to an increase in airway ____.
parenchyma
expiration
resistance
the obstruction of airway outflow can lead to the enlargement of _____ distal to terminal bronchioles.
air spaces (bullae)
Preop treatment for COPD includes
-supportive
-smoking cessation
-bronchodilators and glucocorticoids
-ipratropium (more effective than B2 agonists in COPD)
-treat hypoxemia carefully
Giving oxygen to patients with COPD presents a problem because it can raise ___ in patients who already have CO2 retention.
PaCO2
Giving oxygen to patients with COPD presents a problem because elevating ____ can lead to respiratory failure and it can abolish ______.
PaO2
hypoxic pulmonary vasoconstriction (HPV)
What is the preop managements for COPD
-thorough pulmonary eval
-cardiac eval
-cessation of smoking
-abx if warranted
-review of lung expansion procedures (spirometry)
what is the intraop management for COPD?
-use of minimally invasive surgery
-consider regional anesthesia
-avoid long acting neuromuscular blocking agents
-alines, central lines?
-use of PEEP
-humidified O2
-N2O?
_____ ____ follows prolonged exposure to environmental irritants with a hyper-secretion of mucus and inflammatory changes in the bronchi. There is also a productive cough.
chronic bronchitis
the preop eval for COPD includes?
-assessment of current symptoms (dyspnea, cought, sputum)
-hx of respiratory infection and exercise tolerance
-thorough chest auscultation
-consider PFTs, ABG, CXR, EKG
Preoperatively if the COPD pt exhibits signs of respiratory infection give them ____ and possibly _____ if there is a reversible component present.
antibiotics, bronchodilators
Regional anesthesia may offer benefits for surgery of the extremities and lower abdomen because it is ____ or below.
T10
You must use ____ cautiously because you want to treat post op pain but avoid respiratory depression.
opiods
The advantages to N2O are that it decreases the dose of ____ ____ and it goes quick on and quick off.
volatile anesthetics
one disadvantage of N2) is that it can diffuse into ______ quicker than nitrogen can exit, potentially leading to bullae rupture and tension pneumo.
airspaces
another disadvantage of N2) is that concentrations between ___ and ___ % can limit the concentration of oxygen that can be administered while maintaining the appropriate level of anesthesia.
50-70%
_____ _____ occurs due to air trapping. Also called dynamic hyperinflation. Because air cannot be exhaled, pressure builds up in the lung leading to _______.
-intrinsic PEEP
-positive end expiratory pressure (PEEP)
in COPD there is increased ____ ___ due to airway obstruction. Meaning, all inspire4d air does participate in gas exchange and exhaled gas may not contain a normal amount of ____ measured by capnography.
dead space
CO2
Restrictive lung disease characteristics are?
-decreased vital capacity
-expiratory flow rates remain normal
-FEV1 and FVC will be reduced
-FEV1/FVC is preserved at >0.7
What are the types of intrinsic restrictive pulmonary diseases?
-pulm edema
-ARDS
-Pneumonitis
-idiopathic fibrosis
(may also see an increased AaO2 gradient)
What are the types of extrinsic restrictive pulmonary diseases?
-pleural effusion
-obesity
-kyphoscolisosis
-ascites
-pregnancy
Restrictive pulmonary disease have a decreased lung compliance due to an increase in _________.
extravascular lung fluid
In Restrictive pulmonary disease there should be no ____ surgery. If emergency surgery is needed, oxygenation and ventilation should be optimized
elective
In Restrictive pulmonary disease use _____ support as needed.
pressor
Sarcoidosis causes small lumps which generally heal but if they do not the tissue can remain inflamed and become _____. This can develop into pulmonary fibrosis which distorts the structures of the lungs and can interfere with _____.
scarred
breathing
Also, _____ can occur from sarcoidosis. This is where pockets form in the air tubes of the lungs and become sites for infections.
bronchiectasis
On the flow-volume loop for Restrictive pulmonary disease both ____ and ____ are affected.
inspiration and expiration
People with Restrictive pulmonary disease suffer from increased work of breathing because increased effort is needed to move air in and out of the lungs---less air (_____) is moved per decrease in intrapleural ____.
volume
pressure
Increased PaCO2 in patients with Restrictive pulmonary disease represents _____ disease. Early on these pts may be hypocarbic however late in the disease the patient will live with a higher PaCO2 in return for not working as hard to breathe.
advanced
-hypercarbia and arterial hypoexemia cause vasocontrictive pul htn and cor pulmonale
Regional anesthesia on patients with Restrictive pulmonary disease is similar to regional in other lung disease (safe below T10 as to not impair breathing) however, ____ may be difficult.
positioning
for patients with Restrictive pulmonary disease undergoing GA, _____ and increased ____ may be required.
PEEP and Oxygen
In pts with Restrictive pulmonary disease you can predict post op problems if FVC is less than ____ ml/kg and a preop PaCO2 higher than ___.
15
50
Restrictive pulmonary disease pts by definition have decreased _______. And surgery especially of the abdomen or throax decrease these further. This may make it difficult to clear ______.
preop lung volumes
secretions
It is important that asthma is considered _____ whereas COPD is not.
reversible
if you are giving a neb through an ETT you are losing half of the dose so ___ the dose.
double
Wet airways trigger _____ so make sure to have a dry airway.
laryngospasm
For a COPD patient, dont have insp pressures greater than _____ on pressure mode.
30
To help patients with COPD you can _____ the I:E ratio.
increase
go from 1:2 to 1:3
Know the COPD pts _____ baseline and make sure they are at it when waking up=drive to breathe.
CO2
The ___ position offers optimal access of the lungs, pleura, esophagus, great vessels, vertebrae and other mediastinal structures. It alters normal ____ ____ making the pt at risk for hypoxia. The ____ lung is less compliant.
-lateral
-V/Q relationship
-lower
____ effectively redirects blood flow away from hypoxic or poorly ventilated lung units by the vascular endothelium releasing potent vasocontrcitor peptides called endothelin.
HPV
______ >1 MAC and ____ block HPV.
Volatile anesthetics and N2O
when one side of the chest is opened the negative pressure is ___ and elastic recoil of the lung on that side tends to ______. This can cause progressive hypoxemia and hypercapnia. Effects are overcome by _________.
lost
collapse it
positive pressure ventilation
Mixing of _____ blood from the collapsed upper lung with oxygenated blood from the ventilated dependent lung widens the alveolar to arterial O2 gradient and often results in ______. Fortunately, blood flow to the non ventilated lung is decreased by ___.
hypoxemia
HPV
____ to _____ is poorly matched in mechanically vented pts.
ventilation to perfusion
______ pushes gas into apexes of lung which follows the path of least resistance.
positive pressure ventilation
blood perfuses primarily the ____ parts of lung due in part to the pull of gravity.
dependent
The result of PPV in pts in gas flow to the ____ and blood flow to the ____ resulting in ______ ____.
apex
bases
VQ mismatch
Poorly ventilated alveoli are prone to _____ and ____.
atelectasis and collapse
What are the indications for one lung ventilation (OLV)
-lung resection
-drainage of abscess, cyst or empyema
-bronchopleural fistula
-bronchial tumors
-lung transplant
-persistent intrapulmonary bleeding (PA rupture)
-esophageal surgery
-anterior approach to the thoracic spine
-select open heart procedures
-improve pt outcomes
OLV can improve pt outcomes by restricting _____ or ____ to one lung.
infection or bleeding
OLV can differentially ventilate each lung after trauma, post op or with a ______ fistula.
bronchopleural
Which mainstem bronchus is longer, the left or right?
left
the right upper lobe orifice is ____ cm from the carina and is higher than the left upper lobe orifice at ___ cm.
2.5cm
5cm
the adult trachea is ___-___ cm long
11-13
The trachea begins at the cricoid which is?
C4-C6
The trachea bifurcates at the carina which is?
T4-T6
The right mainstem diverges away at a ___ degree angle. The left mainstem diverges away at a ___ degree angle.
25
45
The following methods are used in OLV.
-double lumen ETT
-single lumen ETT with a built in bronchial blocker
-single lumen ETT with an isolated bronchial blocker (wire guided)
-endobronchial intubation of a single lumen ETT
The disadvantages of single lumen endobronchial tube are?
-inability to ventilate or suction other lung
-if placed in right lung, cannot ventilate right upper lobe
the bronchial blocker is placed under ____ guidance. They are beneficial to patients already ______/_____.
fiberoptic
intubated/trached
The appropriate size double lumen tube for females is ___-___ fr. for males it is ___-___fr.
35-37 (usually 37)
37-39 (usually 39)
in the awake and upright position, you have perfusion to the ____ and lower ventilation from negative pressure generated from spontaneous breaths.
bases
in the asleep and upright position you have perfusion to the ____ (gravity dependent) and ventilation to the ____ because of PPV=V/Q mismatch
bases
upper
In the asleep and lateral position, you have perfusion to the dependent side and ventilation to the ___ lobes from PPV. This is a worsened V/Q mismatch because paralysis, bean bags, open chest
upper
complications of double lumen tubes
-HYPOXIA
-traumatic laryngitis
-tracheal-bronchial rupture
-ETT suturing/stapling in the bronchus
-decreased venous return
Complications of a throacotomy
-volume overload
-broncial disruption
-pneumonia/atelectasis
-pulm htn
-Low CO (r heart failure, decreased preload)
-bleeding
-dysrythmias
-Managing OLV, you should avoid ____.
-To protect HPV, use ____ and narcotics (avoid IAs)
-Use muscle relaxants and atropine
-N2O
-TIVA
During OLV, restrict ____ because lungs are a venous reservoir.
fluids
During OLV you should have an ____ to monitor for decreased venous return and monitor ABG.
Aline
When ventilation a OLV make sure you are using ____% FiO2. Maintain a PIP < ____ by adjusting TV (avoiding major adjustments).
100%
30
If hypoxia develops during OLV you can compensate by?
-PEEP to dependent lung
-CPAP to non dependent lung
-insufflation of O2 to non dependent lung
Preop eval for common thoracic procedures include?
-lab tests
-prescreen for underlying pulm infection
-tracheal stenosis, positional dyspnea, airway collapse, hypoxemia, anatomic narrowing?
-review abg, PFT, CXR, V/Q scan, CT/MRI, angiography
-coexisting patho
Transfuse preop lung pt with pre op Hct less than __%
25%
-T and C 2-4 units of blood
lung cancer patients may have myasthenic syndrome with increased sensitivity to __________.
non depolarizing muscle relaxants
When is the lateral decub position the aline should be in the ____ arm. When doing a mediastinoscopy the aline should be in the ____ arm.
dependent
right
The central line should be in the ______side of neck. Pressure reading may be affected by open chest, lateral position and surgical manipulation.
non dependent
epidural anesthesia reduces volatile agents requirements but epidural anesthesia may create sympathetic blockade and ____.
hypotension
opening the chest produces _____.
pneumothorax
manipulation of the lung, heart, and major vessels may interfere with ______________________ intraop and post op.
ventilatory exchange and cardiovascular stability
the lateral decub position changes the distribution of blood flow and pattern of ventilation and exposes lower lung to danger of contamination by ____, ____ or ____.
secretions, blood or fluids
Open thorax surgery risks include...
-dysrhythmias
-DVT
-PE
-MI
-bronchopleural fistula
-chylothorax
-subq emphysema
-phrenic nerve injury
-recurrent laryngeal nerve injury
Small cell (oat tumors) account for ___% and non small cell tumors account for ____%.
20%
80%
-Often proceeded by bronchoscopy/mediastinoscopy
-lateral or posterior lateral thoracotomy incision
-lateral decub position
-double lumen tube
-time=2-3 hours
-EBL= <500ml
-post op care = ICU
-careful attention to chest tubes
-mortality= +/- 1%
-pain score= 7-8
lung resection
intrapulmonary hemorrhage is characterized by massive hemoptysis r/t trauma, pulm artery rupture, erosion into vessel by trach, abcess or tumor. This requires immediate _____ with ____% FiO2, suctioning the airway, lung iso if unilateral involvement. May need thoracotomy and surgical repair
intubation, 100%
_____ ____ and ____ can be air filled, thin walled, bronchogenic or alveolar destructive, post infective, infantile or emphysematous cysts.
lung cysts & bullae
_____ may rupture cysts or bullae = tension pneumo
positive pressure
Once cysts or bullae are removed, _____ is usually improved.
respiration
key points to remember with cysts and bullae are...?
-PPV < 10cm (may need double lumen tube)
-No N2O
-Extubation-smooth and without coughing
____________ is an autoimmune disorder with prejunctional decreased Ach release and no improvements with anticholinesterases. The peripheral muscles and pelvis are most affected.
myasthenic syndrome-eaton lambert syndrome
The underlying malignancy of myasthenic syndrome is?
small cell cancer of the lung
Symptoms improve with ____ in myasthenic syndrome
exertion
muscle relaxants greatly affect myasthenic syndrome patients. ____ having the most effect.
NDMR
what is a broncho-pleural fistula?
abnormal communication between bronchial tree and pleural cavity with pus.
what causes a broncho-pleural fistula?
pulmonary resection, bronchus or bulla rupture, penetrating chest wound, lung cyst or empyema cavity.
the risks of bronco-pleural fistula are ____ may contaminate healthy lung or cause a tension pneumo.
PPV
The goal with a broncho-pleural fistula is to isolate the _____ lung with a double lumen tube (DLT). Also minimal gas leak through the fistula
affected
-lumen is to the unaffected side
____ is indicated for stenosis, tumor or congenital defect.
tracheal resection
With a tracheal resection patient, you may note ____ and the flow volume loop may help you determine where the obstruction is.
wheezing
with tracheal surgery give minimal _____ to avoid airway obstruction.
premedication
for induction of tracheal surgery consider ______ induction or awake fiberoptic induction to avoid complete obstruction with loss of muscle tone. Questionable muscle relaxants.
inhalation
When emerging a tracheal resection, consider ____ the neck to reduce tension and reduce the risk of re-anastomosis
flexion
What are the three thoracoscopic procedures?
-bronchoscopy
-mediastinoscopy
-bronchoalveolar lavage
The complications of mediastinoscopy procedures include?
-#1 rupture/laceration of the major vessels
-#2 pneumo (hemo) thorax
-intermittent occlusion of the innominate artery (CVA risk)
-tracheal collapse, tension pneumomediastinum, mediastinitis, chylothorax
-phrenic nerve/RLN injury
anesthetic consideration with endoscopy are?
-small ETT vs. DLT
-laser tube and laser precautions
-short acting hypnotic agent
-inhaled agents vs TIVA
-short acting narcotics
-short acting muscle relaxants
-local anesthesia post op
With rigid bronchoscopy you should use _______. The risks/features of rigid include; hypercapnea, hypoxemia, air leaks, anesthesia machine vs HFJV, side arm ventilation port
general anesthesia
complications of endoscopy include?
-facial, dental and laryngeal injury
-airway rupture-pneumo
-hemorrhage
-airway obstruction-blood, edema
_______ for thymectomy, medisinal masses, bilateral pulmonary resection.
median sternotomy/sternotomy
the _____ is the treatment of choice for myastinia gravis patients. it can be done through sternal incision or cervical approach.
thymectomy
_________ is an autoimmune diease with ocular, pharyngeal, and skeletal muscle weakness. It improves with edrophonium 10mg, corticosteroids, immunosuppresants, plasmapheresis and thymectomy.
myasthenia gravis
for myasthenia gravis patients they should hold their anticholinesterase med on _______.
the day of surgery
with myasthenia gravis patients neuromuscular monitoring is indicated but results can be ______.
misleading
myasthenia gravis pts may need to be vented post op if?
-duration of disease greater than 6 years
-coexisting COPD
-anticholinesterase dose greater than 750mg/day
resection of neoplasms, anti-reflux procedures and repair of traumatic or congenital lesions are all indications for?
esophageal surgery
with esophageal surgery you must consider...?
-chronic malnutrition related to cancer/swallowing difficulty
-hypovolemia related to swallowing
-aspiration risk
during esophageal surgery use an aline, CVP and _____. DLT may be indicated and epidural analgesia can be used ____ and _____.
foley
intraop and post op
postoperatively pts with esophageal surgery may need to stay intubated for _________.
aspiration precations
When using the DLT, DL with a ____ MAC blade and advance the tube to at least the ___ cm mark.
3
26cm
what is the most common error associated with DLT insertion?
advancing the tube too far in the bronchus and causing only distal lumen ventilation to one lung
the amount of ____ is the main component of oxygenation. HPV may limit ___ unless it is blunted.
shunt
shunting
The greatest risk of OLV is _________. With that in mind:
TV= 8-10 ml/kg
Adjust RR to keep PaCO2= 40
No PEEP (or less than 5)
Continuous monitoring of O2 and ventilation (SpO2, ABG, ETCO2)
if pulse ox is less than 94% recheck DLT or BB
hypoxemia
What is the O2 management of OLV
-minimize ventilated lung atelectasis
-D/C or avoid N2O to maintain PaO2
-check tube position and suction prn
-PEEP to vented lung (may shunt blood to non ventilated lung)
-CPAP to nonventilated lung (5-8cmH2O)
-Reinflate nonventilated lung with 100% fio2 or have surgeon clamp the PA (last resort)
Intraop blood and fluid requirements of OLV
-IV 2 large bore
-central line
-aline
-restrict IV fluids (1000-1500 ml NS/LR max)
-1 unit autologous blood if available
-vasopressor if hypotensive
-ephedrine 5-10mg
-phenylephrine 50-100mcg
after positioning the patient?
reassess breath sounds, vital signs, monitors, lines and IVs
when the surgeon is finished lung re-exapnsion is done by _____ ventilation, stacking breaths with increasing pressure.
hand
filling the chest with water to determine if there is a leak in the lung is known as the?
lung bubble test
decrease ____ during closing to avoid injury while suturing.
TV
inflating the lungs to 30 cm H2O not only checks for leaks but it also reinflates areas of ____.
atelectasis
the surgeon will insert ______ and drain the pleural cavity and aid in lung re-expansion.
chest tubes
The patient is usually extubated in the OR but if they are remaining intubated, exchange....?
the double lumen tube for a single lumen ETT
chest tubes can be set to water seal or ____cmH2O. Except in pneumonectomy=water seal only.
20
the patient will be transferred to the _____ on monitors and nonrebreathing mask.
ICU
Things to remember...
-watch your field
-interact with your surgeon
A right DLT is rare but it has an extra murpheys eye to ventilate the?
right upper lobe
the gold standard for DLT placement is?
fiberoptic confirmation
When scoping down a DLT you use a ____ scope.
peds
with thoracic surgery it is better to give ____ for fluid replacement/drop in BP
colloids
when inserting an ETT for bronchoscopy, you should have the _____ tube possible.
largest
the blue cuff on the DLT sits in the _____ and the white cuff sits in the _____. the stylet goes through the _____ lumen because it is longer.
bronchus
trachea
bronchial/blue