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6 Cards in this Set

  • Front
  • Back

When does preeclampsia occur?

-20wks after gestation

-upto 6wks after delivery

What is preeclampsia

It is new onset hypertension characterised by proteinuria

Risk factors for preeclampsia

1st pregnancy

Multiple gestations

Maternal age >40yrs <16yrs

Hx of chronic HTN

Chronic renal disease

Distance of >10yrs in btn pregnancies



Fam. Hx

Pathophysiology of preeclampsia

The cause is abnormal development of the placenta

Normaly during pregnancy the spiral arteries(utero placental arteries) dilates to provide adequate perfusion to fetus which is brought about by trophoblastic invasion . In preeclampsia the spiral arteries become fibrous & narrow therefore leading to less fetal perfusion. A hypoperfused placenta releases pro-inflammatory proteins in2 the mother's circulation causing endothelial cell dysfunction that causes vasoconstriction & also affects the kidneys in a way that makes them retain more salt both these result in hypertension.

Aftermath of severe preeclampsia

1. HELLP syndrome

H- hemolysis

E- elevated

L- liver enzymes

L- low

P- platelets

This is because injury to the epithelial cells causes formation of multiple thrombi (uses up platelets), &these thrombi trap and break red cells (hemolysis), & elevated liver enzymes because of poor liver perfusion

2. Generalised edema, pulmonary edema, cerebral edema due to damage of the endothelium causing leakage & missmatch of the starling forces due to low protein from proteinuria. The cerebral edemal presents w headaches, confusion and seizures ( eclampsia)


1.Delivery of the fetus & placenta cause the placenta is the stem of the problem

2.manage symptoms after delivery

3. Additional measures, supplemental oxygen, medication