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10 Cards in this Set
- Front
- Back
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What is a partial seizure
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jerking of limbs and behavioural changes but no loss of consciousness. Abnormal discharge located to relevant area in cortex
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What are the two types of Generalised seizure?
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Petit mal and grand mal. Abnormal electrical activity involves the whole brain.
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What is a grand mal?
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initial generalised tonic convulsion followed by jerking of whole body (clonic convulsion) + sudden loss of consciousness, also referred to as tonic-clonic epilepsy
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What is a petit mal?
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a general seizure, episodic transient loss of consciousness (absence seizures), mainly in children
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What is statue epileptics
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generalised convulsions following each other without consciousness being regained.
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Name 2 Na+ channel blocker use-dependent drugs?
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Carbamazepine, phenytoin
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What kind of seizure does Carbamazepine, phenytoin not work against?
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absence seizures
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Why is Carbamazepine preferred over phenytoin?
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fewer adverse effects
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What are the adverse effects of phenytoin?
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dose-related vertigo, confusion, insomnia, ataxia. Non-dose related rashes, megaloblastic anaemia, teratogenesis, thickening of gums, and increased body hair.
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What are the adverse effects of Carbamazepine?
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unsteadiness, sedation, mental disorientation, and water retention.
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